Ilia Voskoboinik

Overview

Best Publications

• Perforin and granzymes: function, dysfunction and human pathology

  Ilia Voskoboinik;Ilia Voskoboinik;James C. Whisstock;James C. Whisstock;Joseph A. Trapani;Joseph A. Trapani

  1374
  Citations

• CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

  Marian L Burr;Marian L Burr;Marian L Burr;Christina E Sparbier;Yih-Chih Chan;James C Williamson

  930
  Citations

• Perforin-mediated target-cell death and immune homeostasis

  Ilia Voskoboinik;Ilia Voskoboinik;Mark J. Smyth;Mark J. Smyth;Joseph A. Trapani;Joseph A. Trapani

  734
  Citations

• The structural basis for membrane binding and pore formation by lymphocyte perforin

  Ruby H P Law;Natalya Lukoyanova;Ilia Voskoboinik;Ilia Voskoboinik;Tom T Caradoc-Davies

  476
  Citations

• Tumor immune evasion arises through loss of TNF sensitivity

  Conor J. Kearney;Conor J. Kearney;Stephin J. Vervoort;Stephin J. Vervoort;Simon J. Hogg;Simon J. Hogg;Kelly M. Ramsbottom

  382
  Citations

• A Common Fold Mediates Vertebrate Defense and Bacterial Attack

  Carlos J. Rosado;Ashley M. Buckle;Ruby H. P. Law;Rebecca E. Butcher;Rebecca E. Butcher

  335
  Citations

• The MACPF/CDC family of pore-forming toxins.

  Carlos Joaquim Rosado;Stephanie Kondos;Tara Elaina Bull;Michael Kuiper

  330
  Citations

• Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

  Jamie Lopez;Jamie Lopez;Olivia Susanto;Misty Jenkins;Misty Jenkins;Natalya Lukoyanova

  322
  Citations

• Molecular mechanisms of copper homeostasis.

  J. Camakaris;I. Voskoboinik;J.F. Mercer

  296
  Citations

• Perforin: structure, function, and role in human immunopathology

  Ilia Voskoboinik;Michelle Anne Dunstone;Katherine Baran;James Whisstock

  284
  Citations

• Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

  Misty R. Jenkins;Jesse A. Rudd-Schmidt;Jamie A. Lopez;Jamie A. Lopez;Kelly M. Ramsbottom;Kelly M. Ramsbottom

  277
  Citations

• Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

  Ilia Voskoboinik;Marie-Claude Thia;Jamie Fletcher;Annette Ciccone

  205
  Citations

• Apoptosis induced by the lymphocyte effector molecule perforin.

  Paul Bolitho;Ilia Voskoboinik;Ilia Voskoboinik;Joseph A Trapani;Joseph A Trapani;Mark J Smyth;Mark J Smyth

  192
  Citations

• The Molecular Basis for Perforin Oligomerization and Transmembrane Pore Assembly

  Katherine Baran;Michelle Dunstone;Jenny Chia;Annette Ciccone

  174
  Citations

• Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

  Jenny Chia;Kim Pin Yeo;James Whisstock;Michelle Anne Dunstone

  167
  Citations

• Functional analysis of the N-terminal CXXC metal-binding motifs in the human Menkes copper-transporting P-type ATPase expressed in cultured mammalian cells.

  Ilia Voskoboinik;Daniel Strausak;Mark Greenough;Hilary Brooks

  157
  Citations

• Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate.

  Michael J. Petris;Ilia Voskoboinik;Michael Cater;Kathryn Smith

  156
  Citations

• Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells.

  M. Greenough;L. Pase;I. Voskoboinik;M. J. Petris

  141
  Citations

• Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.

  Natalya Lukoyanova;Stephanie C Kondos;Irene Farabella;Ruby H P Law

  139
  Citations

• The Regulation of Catalytic Activity of the Menkes Copper-translocating P-type ATPase ROLE OF HIGH AFFINITY COPPER-BINDING SITES

  Ilia Voskoboinik;Jasmine Mar;Daniel Strausak;James Camakaris

  135
  Citations