Svetlana Lutsenko

Research.com Recognitions

• 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Connecting copper and cancer: from transition metal signalling to metalloplasia.

  Eva J Ge;Ashley I Bush;Angela Casini;Paul A Cobine

  1204
  Citations

• Mechanism of calcium gating in small-conductance calcium-activated potassium channels

  X. M. Xia;B. Fakler;A. Rivard;G. Wayman

  1104
  Citations

• Function and Regulation of Human Copper-Transporting ATPases

  Svetlana Lutsenko;Natalie L. Barnes;Mee Y. Bartee;Oleg Y. Dmitriev

  916
  Citations

• Nature Reviews Disease Primers article: Wilson disease

  Anna Czlonkowska;Tomasz Litwin;Petr Dusek;Peter Ferenci

  653
  Citations

• Organization of P-type ATPases: significance of structural diversity.

  Svetlana Lutsenko;Jack H. Kaplan

  606
  Citations

• Human copper homeostasis: a network of interconnected pathways.

  Svetlana Lutsenko

  478
  Citations

• Identification and analysis of mutations in the Wilson disease gene (ATP7B): population frequencies, genotype-phenotype correlation, and functional analyses.

  A B Shah;I Chernov;H T Zhang;B M Ross

  449
  Citations

• N-terminal Domains of Human Copper-transporting Adenosine Triphosphatases (the Wilson’s and Menkes Disease Proteins) Bind Copper Selectively in Vivo and in Vitro with Stoichiometry of One Copper Per Metal-binding Repeat

  Svetlana Lutsenko;Konstantin Petrukhin;Matthew J. Cooper;Conrad T. Gilliam

  340
  Citations

• Human copper transporters: mechanism, role in human diseases and therapeutic potential.

  Arnab Gupta;Svetlana Lutsenko

  297
  Citations

• Copper handling machinery of the brain

  Svetlana Lutsenko;Ashima Bhattacharjee;Ann L. Hubbard

  253
  Citations

• Function and Regulation of the Mammalian Copper-transporting ATPases: Insights from Biochemical and Cell Biological Approaches

  S Lutsenko;M J Petris

  252
  Citations

• High Copper Selectively Alters Lipid Metabolism and Cell Cycle Machinery in the Mouse Model of Wilson Disease

  Dominik Huster;Tina D. Purnat;Jason L. Burkhead;Martina Ralle

  247
  Citations

• Cellular multitasking: the dual role of human Cu-ATPases in cofactor delivery and intracellular copper balance.

  Svetlana Lutsenko;Arnab Gupta;Jason L. Burkhead;Vesna Zuzel

  242
  Citations

• Null Mutation of the Murine ATP7B (Wilson Disease) Gene Results in Intracellular Copper Accumulation and Late-Onset Hepatic Nodular Transformation

  O. I. Buiakova;Jin Xu;S. Lutsenko;S. Zeitlin

  230
  Citations

• The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.

  Natalie Barnes;Ruslan Tsivkovskii;Natalia Tsivkovskaia;Svetlana Lutsenko

  229
  Citations

• Consequences of copper accumulation in the livers of the Atp7b-/- (Wilson disease gene) knockout mice.

  Dominik Huster;Milton J. Finegold;Clinton T. Morgan;Jason L. Burkhead

  225
  Citations

• Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model

  Tasuku Hirayama;Genevieve C. Van de Bittner;Lawrence W. Gray;Svetlana Lutsenko

  205
  Citations

• An essential role for the extracellular domain of the Na,K-ATPase β-subunit in cation occlusion

  Svetlana Lutsenko;Jack H. Kaplan

  203
  Citations

• Metallochaperone Atox1 Transfers Copper to the NH2-terminal Domain of the Wilson's Disease Protein and Regulates Its Catalytic Activity

  Joel M. Walker;Ruslan Tsivkovskii;Svetlana Lutsenko

  199
  Citations

• Copper regulates cyclic-AMP-dependent lipolysis

  Lakshmi Krishnamoorthy;Joseph A Cotruvo;Jefferson Chan;Jefferson Chan;Harini Kaluarachchi

  189
  Citations