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Dennis J. Thiele

Dennis J. Thiele

D-Index & Metrics

Molecular Biology

D-Index
98
Citations
33651
World Ranking
574
National Ranking
314

Research.com Recognitions

  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Dennis J. Thiele is affiliated with Duke University in the United States. Their research encompasses a range of topics primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The scientist has contributed extensively to subfields such as Molecular Biology, Epidemiology, Infectious Diseases, Cell Biology, and Plant Science.

The research topics covered by Dennis J. Thiele include:

  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Heat shock proteins research
  • Endoplasmic Reticulum Stress and Disease
  • Trace Elements in Health
  • Cytomegalovirus and herpesvirus research
  • Herpesvirus Infections and Treatments

Frequent publication venues for Dennis J. Thiele include:

  • UNC Libraries
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Chemical Biology
  • Science Translational Medicine

Some of the recent papers authored or co-authored by Dennis J. Thiele are:

  • "A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis," 2020, Nature Chemical Biology
  • "Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1," 2020, Science Translational Medicine
  • "Biochemical evidence of both copper chelation and oxygenase activity at the histidine brace," 2020, Scientific Reports
  • "HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia," 2022, Nature Communications
  • "Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation," 2020, Journal of Biological Chemistry

Frequent co-authors collaborating with Dennis J. Thiele include:

  • Sarela García-Santamarina
  • Corinna Probst
  • David R. Loiselle
  • Timothy Haystead
  • Jacob T. Brooks

Dennis J. Thiele has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2006.

Best Publications

  • Mechanisms for copper acquisition, distribution and regulation

    Byung-Eun Kim;Tracy Nevitt;Dennis J Thiele

  • Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

    Seiko Ishida;Jaekwon Lee;Dennis J. Thiele;Ira Herskowitz

  • A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution

    Maria M. O. Peña;Jaekwon Lee;Dennis J. Thiele

  • Copper: an essential metal in biology

    Richard A. Festa;Dennis J. Thiele

  • Molecular mechanisms of copper uptake and distribution

    Sergi Puig;Dennis J Thiele

  • Biochemical Characterization of the Human Copper Transporter Ctr1

    Jaekwon Lee;Maria Marjorette O. Peña;Yasuhiro Nose;Dennis J. Thiele

  • A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium

    Ze-Sheng Li;Yu-Ping Lu;Rui-Guang Zhen;Mark Szczypka

  • Regulation of heat shock transcription factors and their roles in physiology and disease.

    Rocio Gomez-Pastor;Eileen T. Burchfiel;Dennis J. Thiele

  • Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress

    Sang-Gun Ahn;Dennis J. Thiele

  • Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

    Jaekwon Lee;Joseph R. Prohaska;Dennis J. Thiele

  • The Yeast Cadmium Factor Protein (YCF1) Is a Vacuolar Glutathione S-Conjugate Pump*

    Ze-Sheng Li;Mark Szczypka;Yu-Ping Lu;Dennis J. Thiele

  • Coordinated Remodeling of Cellular Metabolism during Iron Deficiency through Targeted mRNA Degradation

    Sergi Puig;Eric Askeland;Dennis J. Thiele

  • Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake.

    Sergi Puig;Jaekwon Lee;Miranda Lau;Dennis J. Thiele

  • Copper is required for oncogenic BRAF signalling and tumorigenesis

    Donita C. Brady;Matthew S. Crowe;Michelle L. Turski;G. Aaron Hobbs

  • Genome-wide analysis of the biology of stress responses through heat shock transcription factor.

    Ji Sook Hahn;Zhanzhi Hu;Dennis J. Thiele;Vishwanath R. Iyer

  • New Roles for Copper Metabolism in Cell Proliferation, Signaling, and Disease

    Michelle L. Turski;Dennis J. Thiele

  • ACE1 regulates expression of the Saccharomyces cerevisiae metallothionein gene.

    D J Thiele

  • A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.

    M.S. Szczypka;J.A. Wemmie;W.S. Moye-Rowley;D.J. Thiele

  • Metal-regulated transcription in eukaryotes.

    Dennis J. Thiele

  • The Arabidopsis heavy metal P-type ATPase HMA5 interacts with metallochaperones and functions in copper detoxification of roots

    Nuria Andrés-Colás;Vicente Sancenón;Susana Rodríguez-Navarro;Sonia Mayo

Frequent Co-Authors

Pengbo Zhou
Pengbo Zhou Cornell University
Christopher M. Counter
Christopher M. Counter Duke University
Katherine J. Franz
Katherine J. Franz Duke University
Joan Selverstone Valentine
Joan Selverstone Valentine University of California, Los Angeles
Vincent Massey
Vincent Massey University of Michigan–Ann Arbor
Joseph R. Prohaska
Joseph R. Prohaska University of Minnesota
Dean H. Hamer
Dean H. Hamer National Institutes of Health
Jeffrey N. Weiser
Jeffrey N. Weiser New York University
James A. Imlay
James A. Imlay University of Illinois at Urbana-Champaign
Joseph Heitman
Joseph Heitman Duke University

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