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Biology and Biochemistry

D-Index
82
Citations
24591
World Ranking
3691
National Ranking
1839

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Valeria C. Culotta is affiliated with Johns Hopkins University in the United States. Their research primarily spans across the fields of Medicine, Environmental Science, and Nursing. Within these broader areas, their work focuses on subfields such as Health, Toxicology and Mutagenesis, Nutrition and Dietetics, Hematology, Infectious Diseases, and Molecular Biology.

The scientist's research addresses several key topics including Trace Elements in Health, Heavy Metal Exposure and Toxicity, Iron Metabolism and Disorders, Antifungal Resistance and Susceptibility, Nanoparticles: Synthesis and Applications, Aluminum Toxicity and Tolerance in Plants and Animals, as well as Legionella and Acanthamoeba Research.

Selected recent papers from Valeria C. Culotta include:

  • Changes in mammalian copper homeostasis during microbial infection, 2020, Metallomics
  • Copper in infectious disease: Using both sides of the penny, 2021, Seminars in Cell and Developmental Biology
  • Expanded role of the Cu-sensing transcription factor Mac1p in Candida albicans, 2020, Molecular Microbiology
  • The role of manganese in morphogenesis and pathogenesis of the opportunistic fungal pathogen Candida albicans, 2023, PLoS Pathogens
  • Cdc42 regulates reactive oxygen species production in the pathogenic yeast Candida albicans, 2021, Journal of Biological Chemistry

Frequent coauthors collaborating with Culotta include Asia S. Wildeman, Brendan P. Cormack, Marika S. David, Edward M. Culbertson, and Naisargi K. Patel.

The scientist's work has been published in several venues multiple times, with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Molecular Microbiology, and Journal of Biological Chemistry. Other publication venues include Metallomics and Seminars in Cell and Developmental Biology.

Valeria C. Culotta was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase.

    T. D. Rae;P. J. Schmidt;R. A. Pufahl;V. C. Culotta

  • Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

    Su Ju Lin;Matt Kaeberlein;Alex A. Andalis;Lori A. Sturtz

  • The Copper Chaperone for Superoxide Dismutase

    Valeria Cizewski Culotta;Leo W.J. Klomp;Jeffrey Strain;Ruby Leah B. Casareno

  • Metallochaperones, an intracellular shuttle service for metal ions.

    Thomas V. O'Halloran;Valeria Cizewski Culotta

  • A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage.

    Lori A. Sturtz;Kerstin Diekert;Laran T. Jensen;Roland Lill

  • Activation of superoxide dismutases: putting the metal to the pedal.

    Valeria Cizewski Culotta;Mei Yang;Thomas V. O'Halloran

  • A Role for the Saccharomyces cerevisiae ATX1 Gene in Copper Trafficking and Iron Transport

    Su Ju Lin;Robert A. Pufahl;Andrew Dancis;Thomas V. O'Halloran

  • Histological Evidence of Protein Aggregation in Mutant SOD1 Transgenic Mice and in Amyotrophic Lateral Sclerosis Neural Tissues

    Mitsunori Watanabe;Margaret Dykes-Hoberg;Valeria Cizewski Culotta;Donald L. Price

  • Identification and Functional Expression of HAH1, a Novel Human Gene Involved in Copper Homeostasis

    Leo W.J. Klomp;Su Ju Lin;Daniel S. Yuan;Richard D. Klausner

  • Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase.

    Philip C. Wong;Darrel Waggoner;Jamuna R. Subramaniam;Lino Tessarollo

  • Superoxide dismutase protects calcineurin from inactivation

    Xutong Wang;Valeria C. Culotta;Claude B. Klee

  • The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity.

    Su Ju Lin;Valeria Cizewski Culotta

  • Battles with iron: manganese in oxidative stress protection.

    J. Dafhne Aguirre;Valeria C. Culotta

  • The yeast copper/zinc superoxide dismutase and the pentose phosphate pathway play overlapping roles in oxidative stress protection.

    Kimberly Hudak Slekar;Daniel J. Kosman;Valeria Cizewski Culotta

  • Saccharomyces cerevisiae Expresses Three Functionally Distinct Homologues of the Nramp Family of Metal Transporters

    Matthew E. Portnoy;Xiu Fen Liu;Valeria Cizewski Culotta

  • Mutations in PMR1 suppress oxidative damage in yeast cells lacking superoxide dismutase.

    Paula J. Lapinskas;Kyle W. Cunningham;Xiu Fen Liu;Gerald R. Fink

  • Factors controlling the uptake of yeast copper/zinc superoxide dismutase into mitochondria.

    Lori Sturtz Field;Yoshiaki Furukawa;Thomas V. O'Halloran;Valeria Cizewski Culotta

  • Identification of a Functional Homolog of the Yeast Copper Homeostasis Gene ATX1 from Arabidopsis

    Edward Himelblau;Helena Mira;Su Ju Lin;Valeria Cizewski Culotta

  • Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae IDENTIFICATION OF PROTEINS PREDICTED TO MEDIATE IRON-SULFUR CLUSTER ASSEMBLY

    Jeffrey Strain;Carrie R. Lorenz;Jacqueline Bode;Stacey Garland

  • SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration

    Amit R. Reddi;Valeria C. Culotta

Frequent Co-Authors

P. John Hart
P. John Hart The University of Texas Health Science Center at San Antonio
Thomas V. O'Halloran
Thomas V. O'Halloran Northwestern University
Joan Selverstone Valentine
Joan Selverstone Valentine University of California, Los Angeles
Don W. Cleveland
Don W. Cleveland University of California, San Diego
Diane E. Cabelli
Diane E. Cabelli Brookhaven National Laboratory
Donald L. Price
Donald L. Price Johns Hopkins University
Ivan Zanoni
Ivan Zanoni Boston Children's Hospital
Jonathan D. Gitlin
Jonathan D. Gitlin Marine Biological Laboratory
Scott G. Filler
Scott G. Filler University of California, Los Angeles
Jose L. Lopez-Ribot
Jose L. Lopez-Ribot The University of Texas at San Antonio

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