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Biology and Biochemistry

D-Index
47
Citations
11096
World Ranking
18602
National Ranking
7604

Overview

Ivan Zanoni is affiliated with Boston Children's Hospital in the United States and has contributed extensively to the study of immunology, infectious diseases, and molecular biology. Their research primarily focuses on the immune system's response to viral infections and immune cell function, with significant attention to COVID-19 and related respiratory pathogens.

The main fields of study for Zanoni include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, Zanoni has developed expertise in several subfields:

  • Immunology
  • Infectious Diseases
  • Molecular Biology
  • Epidemiology
  • Neurology

The major topics covered in Zanoni's work reflect a broad interest in immune mechanisms and viral interactions, including:

  • Immune cells in cancer
  • SARS-CoV-2 and COVID-19 Research
  • Inflammasome and immune disorders
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Zanoni's recent publications provide insight into their research focus and areas of contribution. Notable papers include:

  • "Type III interferons disrupt the lung epithelial barrier upon viral recognition" (2020, Science)
  • "The interferon landscape along the respiratory tract impacts the severity of COVID-19" (2021, Cell)
  • "COVID-19 and emerging viral infections: The case for interferon lambda" (2020, The Journal of Experimental Medicine)
  • "Viral Respiratory Pathogens and Lung Injury" (2021, Clinical Microbiology Reviews)
  • "Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity" (2020, Cell Reports)

Frequent collaborators in Zanoni's work highlight interdisciplinary research efforts. Key co-authors include:

  • Marco Di Gioia
  • Francesco Borriello
  • Roberto Spreafico
  • Valentina Poli
  • Alex G. Cuenca

Zanoni's work has appeared multiple times in prominent publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • iScience
  • Immunity
  • The Journal of Immunology

Best Publications

  • Innate immune pattern recognition: a cell biological perspective.

    Sky W. Brubaker;Kevin S. Bonham;Ivan Zanoni;Jonathan C. Kagan

  • CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

    Ivan Zanoni;Renato Ostuni;Lorri R. Marek;Simona Barresi

  • An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

    Ivan Zanoni;Ivan Zanoni;Yunhao Tan;Marco Di Gioia;Achille Broggi

  • Type III interferons disrupt the lung epithelial barrier upon viral recognition.

    Achille Broggi;Sreya Ghosh;Benedetta Sposito;Benedetta Sposito;Roberto Spreafico

  • CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation

    Ivan Zanoni;Renato Ostuni;Giusy Capuano;Maddalena Collini

  • Role of CD14 in host protection against infections and in metabolism regulation.

    Ivan Zanoni;Francesca Granucci

  • A Contribution of Mouse Dendritic Cell–Derived IL-2 for NK Cell Activation

    Francesca Granucci;Ivan Zanoni;Norman Pavelka;Serani L.H. van Dommelen

  • The interferon landscape along the respiratory tract impacts the severity of COVID-19.

    Benedetta Sposito;Achille Broggi;Laura Pandolfi;Stefania Crotta

  • IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function

    Achille Broggi;Yunhao Tan;Francesca Granucci;Ivan Zanoni;Ivan Zanoni

  • COVID-19 and emerging viral infections: The case for interferon lambda.

    Ludmila Prokunina-Olsson;Noémie Alphonse;Noémie Alphonse;Ruth E. Dickenson;Joan E. Durbin

  • Deciphering the complexity of Toll-like receptor signaling

    Renato Ostuni;Ivan Zanoni;Francesca Granucci

  • By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

    Ivan Zanoni;Ivan Zanoni;Yunhao Tan;Marco Di Gioia;James R. Springstead

  • Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria.

    Yunhao Tan;Ivan Zanoni;Thomas W. Cullen;Andrew L. Goodman

  • Viral Respiratory Pathogens and Lung Injury.

    Nicola Clementi;Sreya Ghosh;Maria De Santis;Matteo Castelli

  • Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion.

    Achille Broggi;Francesca Granucci;Ivan Zanoni;Ivan Zanoni

  • Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity

    Francesca Granucci;Ivan Zanoni;Sonia Feau;Paola Ricciardi‐Castagnoli

  • Central role of dendritic cells in the regulation and deregulation of immune responses

    F. Granucci;I. Zanoni;P. Ricciardi-Castagnoli;P. Ricciardi-Castagnoli

  • Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation.

    Marco Di Gioia;Roberto Spreafico;James R. Springstead;Michael M. Mendelson

  • Toll-like receptor co-receptors as master regulators of the immune response

    Marco Di Gioia;Ivan Zanoni;Ivan Zanoni

  • Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity.

    Dania Zhivaki;Francesco Borriello;Ohn A. Chow;Benjamin Doran

Frequent Co-Authors

Francesca Granucci
Francesca Granucci University of Milano-Bicocca
Paola Ricciardi-Castagnoli
Paola Ricciardi-Castagnoli Toscana Life Sciences Foundation
Jonathan C. Kagan
Jonathan C. Kagan Boston Children's Hospital
Ofer Levy
Ofer Levy Boston Children's Hospital
Simone Guglielmetti
Simone Guglielmetti University of Milano-Bicocca
Matti Karp
Matti Karp Tampere University
Aaron G. Schmidt
Aaron G. Schmidt Ragon Institute of MGH, MIT and Harvard
Jose L. Lopez-Ribot
Jose L. Lopez-Ribot The University of Texas at San Antonio
Massimo Clementi
Massimo Clementi Vita-Salute San Raffaele University
Andreas Wack
Andreas Wack The Francis Crick Institute

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