Hua Lu mainly investigates Molecular biology, Cell biology, Ribosomal protein, Transcription factor II D and Biochemistry. His Molecular biology research includes themes of Ubiquitin, DNA damage, Tumor Protein p73, Transcription and Polyclonal antibodies. His work deals with themes such as General transcription factor, Ubiquitin ligase, Cell growth and Cell cycle checkpoint, which intersect with Cell biology.
His biological study spans a wide range of topics, including Ribosomal RNA, Nuclear protein, Ribosomal protein L5 and Ribosome biogenesis. His Ribosomal RNA study incorporates themes from Ribosomopathy, Ribosome and Biogenesis. His Transcription factor II D research includes elements of Transcription factor II B, RNA polymerase II and RNA polymerase II holoenzyme.
Hua Lu spends much of his time researching Cell biology, Molecular biology, Cancer research, Mdm2 and Ribosomal protein. His work carried out in the field of Cell biology brings together such families of science as Ubiquitin, Ubiquitin ligase and Cell growth. His Molecular biology research is multidisciplinary, relying on both DNA damage, RNA, Nuclear protein, Transcription factor and Transcription.
In his study, microRNA is strongly linked to Gene knockdown, which falls under the umbrella field of Cancer research. The concepts of his Mdm2 study are interwoven with issues in Cancer cell, Wild type, Proto-Oncogene Proteins c-mdm2 and In vitro. Ribosome, Biogenesis, Activator and Ribosomopathy is closely connected to Ribosomal RNA in his research, which is encompassed under the umbrella topic of Ribosomal protein.
His primary areas of investigation include Cell biology, Cancer research, Cancer cell, Mdm2 and Carcinogenesis. Hua Lu has researched Cell biology in several fields, including Suppressor, Ubiquitin, Apoptosis and Cell growth. His study looks at the relationship between Cell growth and topics such as Molecular biology, which overlap with Activator.
Hua Lu has included themes like Phosphodiesterase, Mutant, Gene and Mir 139 5p in his Cancer research study. His study in Cancer cell is interdisciplinary in nature, drawing from both Cell cycle checkpoint, Gene knockdown, Alternative splicing and Ribosomal RNA. His Mdm2 study combines topics in areas such as Cancer, Internal medicine, RRNA processing, Ribosomal protein and Proto-Oncogene Proteins c-mdm2.
His primary areas of study are Cancer research, Cell biology, Mdm2, Proto-Oncogene Proteins c-mdm2 and Ribosomal protein. His Cancer research research includes elements of Bioinformatics, Carcinogenesis, Gene, Phosphodiesterase and Drug resistance. Cell biology and Biogenesis are commonly linked in his work.
The study incorporates disciplines such as Cancer cell, Cancer and Gene knockdown in addition to Mdm2. His Ribosomal protein study integrates concerns from other disciplines, such as Ribosomal RNA and Ectopic expression. His research integrates issues of Cell cycle checkpoint and Molecular biology in his study of Ribosome.
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Endostatin induces endothelial cell apoptosis.
Mohanraj Dhanabal;Ramani Ramchandran;Matthew J.F. Waterman;Hua Lu.
Journal of Biological Chemistry (1999)
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
Zhi-Min Yuan;Hisashi Shioya;Takatoshi Ishiko;Xiangao Sun.
Nature (1999)
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
Marcie Colledge;Eric M. Snyder;Robert A. Crozier;Jacquelyn A. Soderling.
Neuron (2003)
Signaling to p53: ribosomal proteins find their way.
Yanping Zhang;Hua Lu.
Cancer Cell (2009)
Inhibition of MDM2-mediated p53 Ubiquitination and Degradation by Ribosomal Protein L5
Mu Shui Dai;Hua Lu.
Journal of Biological Chemistry (2004)
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II
Hua Lu;Leigh Zawel;Laurent Fisher;Jean-Marc Egly.
Nature (1992)
Ribosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition
Mu Shui Dai;Shelya X. Zeng;Yetao Jin;Xiao Xin Sun.
Molecular and Cellular Biology (2004)
Human TAFII31 protein is a transcriptional coactivator of the p53 protein.
Hua Lu;Arnold J. Levine.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Ribosomal proteins: functions beyond the ribosome
Xiang Zhou;Wen-Juan Liao;Jun-Ming Liao;Peng Liao.
Journal of Molecular Cell Biology (2015)
Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II
Arik Dvir;Scott R. Peterson;Mark W. Knuth;Hua Lu.
Proceedings of the National Academy of Sciences of the United States of America (1992)
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