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Medicine

D-Index
126
Citations
52824
World Ranking
2986
National Ranking
24

Overview

Ka-Fai To is affiliated with the Chinese University of Hong Kong in China. Their research spans primarily across the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on molecular biology and oncology.

The main subfields of their work include:

  • Molecular Biology
  • Oncology
  • Immunology
  • Cancer Research
  • Pulmonary and Respiratory Medicine

Their research topics cover a range of areas related to cancer biology and immunology, including:

  • Immune cells in cancer
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Pancreatic and Hepatic Oncology Research
  • Cancer Cells and Metastasis
  • Cancer Immunotherapy and Biomarkers
  • Cancer-related molecular mechanisms research

Recent publications highlight diverse contributions to oncology and related biomedical fields. Notable papers include:

  • "Nasopharyngeal carcinoma: an evolving paradigm," 2021, Nature Reviews Clinical Oncology
  • "Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets," 2024, Signal Transduction and Targeted Therapy
  • "CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA-Binding Proteins and Sponging MiR-942," 2020, Cancer Research
  • "Targeting m 6 A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer," 2023, Gut
  • "Smad3 Promotes Cancer-Associated Fibroblasts Generation via Macrophage-Myofibroblast Transition," 2021, Advanced Science

Ka-Fai To has collaborated frequently with several researchers, including:

  • Wei Kang
  • Jun Yu
  • Bonan Chen
  • Alvin Ho-Kwan Cheung
  • Patrick Ming-Kuen Tang

The scientist has published extensively in venues that focus on oncology and cancer biology. Frequent publication platforms include:

  • Cancer Research
  • Nature Communications
  • Oncogene
  • Cancer Letters
  • Gut

Best Publications

  • A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong

    Nelson Lee;David Hui;Alan Wu;Paul Chan

  • Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non–Small-Cell Lung Cancer in Asia (IPASS)

    Masahiro Fukuoka;Yi Long Wu;Sumitra Thongprasert;Patrapim Sunpaweravong

  • Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding.

    Francis K L Chan;Jessica Y L Ching;Lawrence C T Hung;Vincent W S Wong

  • Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection.

    Wai K Leung;Ka-fai To;Paul K.S Chan;Henry L.Y Chan

  • Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis.

    Francis K L Chan;Lawrence C T Hung;Bing Y Suen;Justin C Y Wu

  • Haematological manifestations in patients with severe acute respiratory syndrome : retrospective analysis

    Raymond S M Wong;Alan Wu;K F To;Nelson Lee

  • Focus on nasopharyngeal carcinoma.

    Kwok Wai Lo;Ka Fai To;Dolly P Huang

  • Pathology of fatal human infection associated with avian influenza A H5N1 virus.

    Ka-Fai To;Paul K.S. Chan;Kui-Fat Chan;Wai-Ki Lee

  • An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival

    Elizabeth Yee-Wai Choy;Kam-Leung Siu;Kin-Hang Kok;Raymond Wai-Ming Lung

  • Randomised trial of eradication of Helicobacter pylori before non-steroidal anti-inflammatory drug therapy to prevent peptic ulcers

    Francis K L Chan;Joseph J Y Sung;S C Sydney Chung;K F To

  • Acute renal impairment in coronavirus-associated severe acute respiratory syndrome

    Kwok Hong Chu;Wai Kay Tsang;Colin S. Tang;Man Fai Lam

  • MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

    Queenie W.–L. Wong;Raymond W.–M. Lung;Priscilla T.–Y. Law;Paul B.–S. Lai

  • Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection1 1The authors thank Man-yee Yung, Sara Fung, Dr. Bonnie Kwan, and Dr. Thomas Li for their help in retrieving patient information.

    Wai K Leung;Ka-fai To;Paul K.S Chan;Henry L.Y Chan

  • Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non–Small Cell Lung Cancer Patients

    Tony K F Yung;K. C Allen Chan;Tony S K Mok;Joanna Tong

  • Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial

    Francis K L Chan;K F To;Justin C Y Wu;M Y Yung

  • Modulation of LMP1 protein expression by EBV-encoded microRNAs

    Angela Kwok Fung Lo;Ka Fai To;Kwok Wai Lo;Raymond Wai Ming Lung

  • miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

    Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

  • High Frequency of Promoter Hypermethylation of RASSF1A in Nasopharyngeal Carcinoma

    Kwok-Wai Lo;Joseph Kwong;Angela Bik-Yu Hui;Sylvia Yat-Yee Chan

  • MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non-Small Cell Lung Carcinoma with Poor Prognosis.

    Joanna H. Tong;Sai F. Yeung;Anthony W.H. Chan;Lau Y. Chung

  • Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival.

    Edwin Pun Hui;Anthony Tak-cheung Chan;Francesco Pezzella;Helen Turley

Frequent Co-Authors

Joseph J.Y. Sung
Joseph J.Y. Sung Nanyang Technological University
Jun Yu
Jun Yu Chinese University of Hong Kong
Kwok Wai Lo
Kwok Wai Lo Chinese University of Hong Kong
Paul B.S. Lai
Paul B.S. Lai Chinese University of Hong Kong
Anthony W.H. Chan
Anthony W.H. Chan Chinese University of Hong Kong
Wai K. Leung
Wai K. Leung University of Hong Kong
Stephen L. Chan
Stephen L. Chan Chinese University of Hong Kong
Francis K.L. Chan
Francis K.L. Chan Chinese University of Hong Kong
Paul K.S. Chan
Paul K.S. Chan Chinese University of Hong Kong
Anthony T.C. Chan
Anthony T.C. Chan Chinese University of Hong Kong

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