World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
92
Citations
33890
World Ranking
11235
National Ranking
124

Overview

Paul B.S. Lai is affiliated with the Chinese University of Hong Kong in China and has a substantial body of research in medicine, with a focus on surgery, hepatology, oncology, molecular biology, and pulmonary and respiratory medicine.

The scientist's work covers key topics including hepatocellular carcinoma treatment and prognosis, cholangiocarcinoma and gallbladder cancer studies, cardiac, anesthesia and surgical outcomes, liver disease diagnosis and treatment, pancreatic and hepatic oncology research, surgical simulation and training, and innovations in medical education.

Frequent publication venues for their research include:

  • Surgical Practice
  • HPB
  • The Surgeon
  • Cancer Research
  • Annals of Hepato-Biliary-Pancreatic Surgery

Notable recent papers authored or co-authored by Paul B.S. Lai include:

  • Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services, 2020, British Journal of Surgery
  • A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma, 2021, Science Translational Medicine
  • Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver, 2022, Cellular and Molecular Immunology
  • Prospective double-blinded randomized controlled trial of Microwave versus RadioFrequency Ablation for hepatocellular carcinoma (McRFA trial), 2020, HPB
  • FOX transcription factor family in hepatocellular carcinoma, 2020, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

The scientist has collaborated frequently with several co-authors, including:

  • Charing C. N. Chong
  • Kelvin K. Ng
  • Kit-Fai Lee
  • John Wong
  • A. Fung

Paul B.S. Lai's main field of study is medicine, with a significant number of publications (187) reflecting expertise across multiple subfields:

  • Surgery
  • Hepatology
  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine

Best Publications

  • Assessment of Liver Function in Patients With Hepatocellular Carcinoma: A New Evidence-Based Approach—The ALBI Grade

    Philip J. Johnson;Sarah Berhane;Chiaki Kagebayashi;Shinji Satomura

  • Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial

    Ka Lau Leung;Samuel P Y Kwok;Steve C W Lam;Janet F Y Lee

  • Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: A study based on 926 patients

    Thomas W. T. Leung;Amanda M. Y. Tang;Benny Zee;W. Y. Lau

  • A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma.

    Winnie Yeo;Tony S. Mok;Benny Zee;Thomas W. T. Leung

  • Detection of Aberrant p16 Methylation in the Plasma and Serum of Liver Cancer Patients

    Ivy H.N. Wong;Y. M.Dennis Lo;Jun Zhang;Choong Tsek Liew

  • Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

    Kun Sun;Peiyong Jiang;K. C. Allen Chan;John Wong

  • Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services.

    Kjetil Søreide;Kjetil Søreide;Julie Hallet;Jeffrey B. Matthews;Andreas Anton Schnitzbauer

  • Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

    Peiyong Jiang;Carol W.M. Chan;K. C.Allen Chan;Suk Hang Cheng

  • Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

    K. C.Allen Chan;Peiyong Jiang;Yama W.L. Zheng;Gary J.W. Liao

  • Randomized trial of early versus delayed laparoscopic cholecystectomy for acute cholecystitis

    P. B. S. Lai;K. H. Kwong;K. L. Leung;S. P. Y. Kwok

  • MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

    Queenie W.–L. Wong;Raymond W.–M. Lung;Priscilla T.–Y. Law;Paul B.–S. Lai

  • Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

    K. C. Allen Chan;Peiyong Jiang;Carol W. M. Chan;Kun Sun

  • miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

    Stephanie Ma;Kwan Ho Tang;Yuen Piu Chan;Terence K. Lee

  • Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection.

    Anthony W.H. Chan;Jianhong Zhong;Sarah Berhane;Hidenori Toyoda

  • Systemic Cytokine Response After Laparoscopic-Assisted Resection of Rectosigmoid Carcinoma: A Prospective Randomized Trial

    Ka Lau Leung;Paul B. S. Lai;Rocky L. K. Ho;William C. S. Meng

  • Polypoid lesions of the gallbladder.

    Kit Fai Lee;John Wong;Jimmy Chak Man Li;Paul Bo San Lai

  • Assessment of Genetic Changes in Hepatocellular Carcinoma by Comparative Genomic Hybridization Analysis: Relationship to Disease Stage, Tumor Size, and Cirrhosis

    Nathalie Wong;Paul Lai;Siu-Wah Lee;Susanna Fan

  • MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling

    Queenie W-L Wong;Arthur K-K Ching;Anthony W-H Chan;Kwong-Wai Choy

  • CD133+ liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling†‡

    Kwan Ho Tang;Stephanie Ma;Terence K. Lee;Yuen Piu Chan

  • Viral-human chimeric transcript predisposes risk to liver cancer development and progression

    Chi-Chiu Lau;Tingting Sun;Arthur K.K. Ching;Mian He

Frequent Co-Authors

John Wong
John Wong University of Hong Kong
Ka-Fai To
Ka-Fai To Chinese University of Hong Kong
Stephen L. Chan
Stephen L. Chan Chinese University of Hong Kong
Philip J. Johnson
Philip J. Johnson University of Liverpool
Winnie Yeo
Winnie Yeo Chinese University of Hong Kong
Wan Yee Lau
Wan Yee Lau Chinese University of Hong Kong
Joseph J.Y. Sung
Joseph J.Y. Sung Nanyang Technological University
Henry Lik-Yuen Chan
Henry Lik-Yuen Chan Chinese University of Hong Kong
Anthony W.H. Chan
Anthony W.H. Chan Chinese University of Hong Kong
Vincent Wai-Sun Wong
Vincent Wai-Sun Wong Chinese University of Hong Kong

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