World's Best Scientists 2026 revealed!
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Best Female Scientists
2025
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Biology and Biochemistry
UK
2026

D-Index & Metrics

Best Female Scientists

D-Index
130
Citations
93559
World Ranking
347
National Ranking
32

Molecular Biology

D-Index
126
Citations
94311
World Ranking
209
National Ranking
12

Biology and Biochemistry

D-Index
133
Citations
98491
World Ranking
367
National Ranking
21

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2018 - Member of the National Academy of Sciences
  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 2004 - Fellow of the Royal Society of Edinburgh

Overview

Karen H. Vousden is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. The scientist's contributions focus on several subfields, including Molecular Biology, Cancer Research, Oncology, Immunology, and Physiology.

Their research covers a diverse range of topics such as Cancer, Hypoxia, and Metabolism; Cancer-related Molecular Pathways; Cancer Research and Treatments; Epigenetics and DNA Methylation; Amino Acid Enzymes and Metabolism; Immune Cell Function and Interaction; and Diet and Metabolism studies.

Recent publications reflect a focus on the molecular mechanisms underlying cancer and the systemic nature of the disease. Notable papers include:

  • The role of ROS in tumour development and progression (2022, Nature reviews. Cancer)
  • Embracing cancer complexity: Hallmarks of systemic disease (2024, Cell)
  • p53, cancer and the immune response (2020, Journal of Cell Science)
  • Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy (2021, Nature Communications)
  • Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer (2020, Cancer Cell)

The scientist frequently publishes in journals such as Nature Communications, Genes & Development, Nature Cancer, bioRxiv (Cold Spring Harbor Laboratory), and Cancer Cell.

Collaboration has been a significant aspect of their work, with recurring coauthors including Eric C. Cheung, Karen Blyth, Nathalie Legrave, Julianna Blagih, and Mylène Tajan.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Regulation of p53 stability by Mdm2

    Michael H. G. Kubbutat;Stephen N. Jones;Karen H. Vousden

  • Live or let die: the cell's response to p53

    Karen H. Vousden;Xin Lu

  • Proliferation, cell cycle and apoptosis in cancer

    Gerard I. Evan;Karen H. Vousden

  • Blinded by the Light: The Growing Complexity of p53

    Karen H. Vousden;Carol Prives

  • PUMA, a novel proapoptotic gene, is induced by p53.

    Katsunori Nakano;Karen H Vousden

  • p53 in health and disease.

    Karen H. Vousden;David P. Lane

  • TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

    Karim Bensaad;Atsushi Tsuruta;Mary A. Selak;M. Nieves Calvo Vidal

  • p53 mutations in cancer

    Patricia A. J. Muller;Karen H. Vousden

  • Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

    Patricia A.J. Muller;Karen H. Vousden

  • The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

    Francesca J. Stott;Stewart Bates;Marion C. James;Beth B. McConnell

  • Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

    Shengyun Fang;Jane P. Jensen;Robert L. Ludwig;Karen H. Vousden

  • p14ARF links the tumour suppressors RB and p53.

    Stewart Bates;Andrew C. Phillips;Paula A. Clark;Francesca Stott

  • p53 and metabolism

    Karen H. Vousden;Kevin M. Ryan

  • p53 in survival, death and metabolic health: a lifeguard with a licence to kill

    Flore Kruiswijk;Christiaan F. Labuschagne;Karen H. Vousden

  • HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.

    P. Hawley-Nelson;K.H. Vousden;N.L. Hubbert;D.R. Lowy

  • p53: death star.

    Karen H Vousden

  • Role of NF-κB in p53-mediated programmed cell death

    Kevin M. Ryan;Mary K. Ernst;Nancy R. Rice;Karen H. Vousden

  • Regulation and function of the p53 tumor suppressor protein.

    Kevin M Ryan;Andrew C Phillips;Karen H Vousden

  • Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

    Oliver D. K. Maddocks;Celia R. Berkers;Susan M. Mason;Liang Zheng

Frequent Co-Authors

Kevin M. Ryan
Kevin M. Ryan University of Glasgow
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Karen Blyth
Karen Blyth University of Glasgow
Owen J. Sansom
Owen J. Sansom University of Glasgow
Eyal Gottlieb
Eyal Gottlieb Technion – Israel Institute of Technology
Jim C. Norman
Jim C. Norman University of Glasgow
Moshe Oren
Moshe Oren Weizmann Institute of Science
Colin Nixon
Colin Nixon University of Glasgow
Gordon Peters
Gordon Peters Cancer Research UK London Research Institute
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University

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