Julian F. B. Mercer

Overview

Best Publications

• Isolation of a partial candidate gene for Menkes disease by positional cloning.

  Julian F. B. Mercer;Janie Livingston;Bryan Hall;Jennifer A. Paynter

  811
  Citations

• Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases.

  Daniel Strausak;Julian F.B Mercer;Hermann H Dieter;Wolfgang Stremmel

  660
  Citations

• Metabolism and functions of copper in brain.

  Ivo F. Scheiber;Julian F.B. Mercer;Ralf Dringen

  513
  Citations

• Trafficking of the copper-ATPases, ATP7A and ATP7B: Role in copper homeostasis

  Sharon La Fontaine;Julian F.B. Mercer

  478
  Citations

• The molecular basis of copper-transport diseases.

  Julian F.B Mercer

  404
  Citations

• Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

  Anthony R White;Rosario Reyes;Rosario Reyes;Julian F.B Mercer;Julian F.B Mercer;James Camakaris

  357
  Citations

• Copper: effects of deficiency and overload.

  Ivo Scheiber;Ralf Dringen;Julian F. B. Mercer

  304
  Citations

• Molecular mechanisms of copper homeostasis.

  J. Camakaris;I. Voskoboinik;J.F. Mercer

  296
  Citations

• The Menkes Copper Transporter Is Required for the Activation of Tyrosinase

  Michael J. Petris;Daniel Strausak;Julian F.B. Mercer

  258
  Citations

• Copper pathology in vulnerable brain regions in Parkinson's disease.

  Katherine M. Davies;Katherine M. Davies;Sylvain Bohic;Sylvain Bohic;Sylvain Bohic;Asunción Carmona;Asunción Carmona;Richard Ortega;Richard Ortega

  251
  Citations

• Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux

  James Camakaris;Michael J. Petris;Leanne Bailey;Peiyan Shen

  215
  Citations

• The Menkes protein (ATP7A; MNK) cycles via the plasma membrane both in basal and elevated extracellular copper using a C-terminal di-leucine endocytic signal.

  Michael J. Petris;Julian F.B. Mercer

  211
  Citations

• The molecular basis of copper homeostasis copper-related disorders.

  Roxana M. Llanos;Julian F.B. Mercer

  205
  Citations

• Missense mutations in the copper transporter gene ATP7A cause X-linked distal hereditary motor neuropathy.

  Marina L. Kennerson;Marina L. Kennerson;Garth A. Nicholson;Garth A. Nicholson;Stephen G. Kaler;Bartosz Kowalski

  200
  Citations

• Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

  Blaine R Roberts;Nastasia K H Lim;Erin J McAllum;Paul S Donnelly

  198
  Citations

• The Role of GMXCXXC Metal Binding Sites in the Copper-induced Redistribution of the Menkes Protein

  Daniel Strausak;Sharon La Fontaine;Joanne Hill;Stephen D. Firth

  195
  Citations

• A C-terminal di-leucine is required for localization of the Menkes protein in the trans-Golgi network.

  Michael J. Petris;Michael J. Petris;James Camakaris;Mark Greenough;Sharon LaFontaine

  175
  Citations

• ATP7B Mediates Vesicular Sequestration of Copper: Insight Into Biliary Copper Excretion

  Michael A. Cater;Sharon La Fontaine;Kristy Shield;Yolanda Deal

  161
  Citations

• Functional analysis of the N-terminal CXXC metal-binding motifs in the human Menkes copper-transporting P-type ATPase expressed in cultured mammalian cells.

  Ilia Voskoboinik;Daniel Strausak;Mark Greenough;Hilary Brooks

  157
  Citations

• Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate.

  Michael J. Petris;Ilia Voskoboinik;Michael Cater;Kathryn Smith

  156
  Citations