2026 Tohru Fukai: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	58	12973	11937	5531	4949	207	16634

Overview

Tohru Fukai is affiliated with the Veterans Health Administration in the United States and conducts research primarily in biochemistry, genetics, molecular biology, and medicine. Their work is strongly focused on molecular biology, physiology, immunology, cancer research, and nutrition and dietetics.

The scientist's research covers several main topics including:

Angiogenesis and VEGF in Cancer
Trace Elements in Health
Cancer, Hypoxia, and Metabolism
Nitric Oxide and Endothelin Effects
Nuclear Receptors and Signaling
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Adenosine and Purinergic Signaling

Tohru Fukai has contributed to a number of frequently cited publications. Some recent papers include:

Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis, 2020, published in Cells
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis, 2022, published in Nature Cell Biology
The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2, 2021, published in Nature Communications
Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease, 2021, published in Antioxidants and Redox Signaling
Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer, 2020, published in PLoS ONE

The scientist frequently collaborates with several researchers, including:

Masuko Ushio-Fukai
Sudhahar Varadarajan
Archita Das
Dipankar Ash
Malgorzata McMenamin

Tohru Fukai has published extensively in well-known scientific venues such as:

Circulation
Free Radical Biology and Medicine
bioRxiv (Cold Spring Harbor Laboratory)
Journal of Molecular and Cellular Cardiology
Circulation Research

Best Publications

Superoxide dismutases: role in redox signaling, vascular function, and diseases.

Tohru Fukai;Masuko Ushio-Fukai

2139
Citations
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Ulf Landmesser;Sergey Dikalov;S. Russ Price;Louise McCann

2017
Citations
Endothelial Regulation of Vasomotion in ApoE-Deficient Mice: Implications for Interactions Between Peroxynitrite and Tetrahydrobiopterin

Jørn Bech Laursen;Mark Somers;Sabine Kurz;Louise McCann

911
Citations
Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training

Tohru Fukai;Martin R. Siegfried;Masuko Ushio-Fukai;Yian Cheng

780
Citations
Novel Role of gp91phox-Containing NAD(P)H Oxidase in Vascular Endothelial Growth Factor–Induced Signaling and Angiogenesis

Masuko Ushio-Fukai;Yan Tang;Tohru Fukai;Sergey I. Dikalov

592
Citations
Atrial fibrillation increases production of superoxide by the left atrium and left atrial appendage: role of the NADPH and xanthine oxidases

Samuel C. Dudley;Nyssa E. Hoch;Louise A. McCann;Clegg Honeycutt

490
Citations
Extracellular superoxide dismutase and cardiovascular disease

Tohru Fukai;Rodney J Folz;Ulf Landmesser;David G Harrison

475
Citations
Copper and angiogenesis: unravelling a relationship key to cancer progression.

Lydia Finney;Stefan Vogt;Tohru Fukai;David Glesne

387
Citations
Shear Stress Modulates Expression of Cu/Zn Superoxide Dismutase in Human Aortic Endothelial Cells

Nobutaka Inoue;Santhini Ramasamy;Tohru Fukai;Robert M. Nerem

366
Citations
Peroxidase Properties of Extracellular Superoxide Dismutase: Role of Uric Acid in Modulating In Vivo Activity

H. Ulrich Hink;Nalini Santanam;Sergey Dikalov;Louise McCann

350
Citations
Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent Transcription Factor Involved in Cell Proliferation

Shinichi Itoh;Ha Won Kim;Ha Won Kim;Osamu Nakagawa;Kiyoshi Ozumi;Kiyoshi Ozumi

301
Citations
Shear Stress Regulates Endothelial Nitric-oxide Synthase Promoter Activity through Nuclear Factor κB Binding

Michael E. Davis;Isabella M. Grumbach;Tohru Fukai;Alexis Cutchins

290
Citations
IQGAP1, a Novel Vascular Endothelial Growth Factor Receptor Binding Protein, Is Involved in Reactive Oxygen Species—Dependent Endothelial Migration and Proliferation

Minako Yamaoka-Tojo;Masuko Ushio-Fukai;Lula Hilenski;Sergey I. Dikalov

287
Citations
Modulation of Extracellular Superoxide Dismutase Expression by Angiotensin II and Hypertension

Tohru Fukai;Martin R. Siegfried;Masuko Ushio-Fukai;Kathy K. Griendling

277
Citations
Role of Extracellular Superoxide Dismutase in Hypertension

Maria Carolina Gongora;Zhenyu Qin;Karine Laude;Ha Won Kim

255
Citations
Vascular expression of extracellular superoxide dismutase in atherosclerosis.

Tohru Fukai;Zorina S. Galis;Zorina S. Galis;Xiao Ping Meng;Sampath Parthasarathy;Sampath Parthasarathy

225
Citations
Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis

Tohru Fukai;Masuko Ushio-Fukai

224
Citations
Role of Nox2-Based NADPH Oxidase in Bone Marrow and Progenitor Cell Function Involved in Neovascularization Induced by Hindlimb Ischemia

Norifumi Urao;Hyoe Inomata;Masooma Razvi;Ha Won Kim

219
Citations
ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis.

Young-Mee Kim;Young-Mee Kim;Seok-Jo Kim;Seok-Jo Kim;Ryosuke Tatsunami;Hisao Yamamura

212
Citations
Role of Protein Tyrosine Phosphatase 1B in Vascular Endothelial Growth Factor Signaling and Cell–Cell Adhesions in Endothelial Cells

Yoshimasa Nakamura;Nikolay Patrushev;Hyoe Inomata;Dolly Mehta

211
Citations