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Biology and Biochemistry

D-Index
60
Citations
13816
World Ranking
11894
National Ranking
5109

Overview

Betsy A. Hirsch is affiliated with the University of Minnesota in the United States and has contributed extensively to research in the fields of medicine, particularly focusing on hematology and molecular biology.

Their research covers several subfields, including:

  • Hematology
  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Oncology
  • Infectious Diseases

The main topics of their work include:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Protein Degradation and Inhibitors
  • Chronic Myeloid Leukemia Treatments
  • Histone Deacetylase Inhibitors Research
  • Hematopoietic Stem Cell Transplantation
  • Neutropenia and Cancer Infections

Hirsch has published numerous papers, with notable recent publications including:

  • "Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children's Oncology Group," 2020, Haematologica
  • "Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531," 2021, Journal of Clinical Oncology
  • "Assessment of Arsenic Trioxide and All-trans Retinoic Acid for the Treatment of Pediatric Acute Promyelocytic Leukemia," 2021, JAMA Oncology
  • "Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia," 2023, Haematologica
  • "Phase I/II Study of CPX-351 Followed by Fludarabine, Cytarabine, and Granulocyte-Colony Stimulating Factor for Children With Relapsed Acute Myeloid Leukemia: A Report From the Children's Oncology Group," 2020, Journal of Clinical Oncology

Their frequent co-authors include:

  • Todd A. Alonzo
  • Richard Aplenc
  • Alan S. Gamis
  • Soheil Meshinchi
  • E. Anders Kolb

Hirsch's work has been published mainly in venues such as:

  • Blood
  • Journal of Clinical Oncology
  • Blood Advances
  • Cancer Genetics
  • American Journal of Respiratory and Critical Care Medicine

Best Publications

  • Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia

    Jeremy W Fox;Jeremy W Fox;Edward D Lamperti;Yaman Z Ekşioğlu;Susan E Hong

  • Evidence for evolutionary conservation of sex-determining genes

    Christopher S. Raymond;Caroline E. Shamu;Caroline E. Shamu;Michael M. Shen;Michael M. Shen;Kelly J. Seifert

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development.

    Christopher S. Raymond;Jae R. Kettlewell;Betsy Hirsch;Vivian J. Bardwell

  • DNA Ligase IV Mutations Identified in Patients Exhibiting Developmental Delay and Immunodeficiency

    Mark O'Driscoll;Karen M. Cerosaletti;Pierre M. Girard;Yan Dai

  • Gemtuzumab Ozogamicin in Children and Adolescents With De Novo Acute Myeloid Leukemia Improves Event-Free Survival by Reducing Relapse Risk: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531

    Alan S. Gamis;Todd A. Alonzo;Soheil Meshinchi;Lillian Sung

  • A Region of Human Chromosome 9p Required for Testis Development Contains Two Genes Related to Known Sexual Regulators

    Christopher S. Raymond;Emily D. Parker;Jae R. Kettlewell;Laura G. Brown

  • Residual disease detected by multidimensional flow cytometry signifies high relapse risk in patients with de novo acute myeloid leukemia: a report from Children's Oncology Group.

    Michael R. Loken;Todd A. Alonzo;Todd A. Alonzo;Laura Pardo;Robert B. Gerbing

  • Technical Standards and Guidelines for Fragile X: The First of a Series of Disease-Specific Supplements to the Standards and Guidelines for Clinical Genetics Laboratories of the American College of Medical Genetics

    Anne Maddalena;Carolyn Sue Richards;Matthew J McGinniss;Arthur Brothman

  • Somatic mosaicism in Fanconi anemia: Evidence of genotypic reversion in lymphohematopoietic stem cells

    John J. Gregory;John E. Wagner;Peter C. Verlander;Orna Levran

  • X-linked malformations of neuronal migration

    W. B. Dobyns;E. Andermann;F. Andermann;D. Czapansky-Beilman

  • Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood.

    Betsy Hirsch;Akiko Shimamura;Lisa Moreau;Shari Baldinger

  • AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group.

    Todd M. Cooper;Janet Franklin;Robert B. Gerbing;Todd A. Alonzo

  • AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression.

    Yingming Li;Tae Hyun Hwang;LeAnn Oseth;Adam Hauge

  • Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML

    Jessica A. Pollard;Jessica A. Pollard;Todd A. Alonzo;Robert B. Gerbing;Phoenix A. Ho;Phoenix A. Ho

  • Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group.

    Phoenix A. Ho;Phoenix A. Ho;Todd A. Alonzo;Todd A. Alonzo;Robert B. Gerbing;Jessica Pollard;Jessica Pollard;Jessica Pollard

  • American College of Medical Genetics and Genomics: standards and guidelines for documenting suspected consanguinity as an incidental finding of genomic testing.

    Catherine W. Rehder;Karen L. David;Betsy A Hirsch;Helga V. Toriello

  • Guidance for Fluorescence in Situ Hybridization Testing in Hematologic Disorders

    Daynna J. Wolff;Adam Bagg;Linda D. Cooley;Gordon W. Dewald

  • CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children’s Oncology Group Trial AAML0531

    Jatinder K. Lamba;Lata Chauhan;Miyoung Shin;Michael R. Loken

  • CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children’s Oncology Group Trial AAML0531

    Jessica A. Pollard;Michael Loken;Robert B. Gerbing;Susana C. Raimondi

Frequent Co-Authors

Todd A. Alonzo
Todd A. Alonzo University of Southern California
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital
Michael R. Loken
Michael R. Loken Fred Hutchinson Cancer Research Center
Lillian Sung
Lillian Sung University of Toronto
Irwin D. Bernstein
Irwin D. Bernstein Fred Hutchinson Cancer Research Center
Beverly J. Lange
Beverly J. Lange Children's Hospital of Philadelphia
Nyla A. Heerema
Nyla A. Heerema The Ohio State University
Jerald P. Radich
Jerald P. Radich Fred Hutchinson Cancer Research Center
John E. Wagner
John E. Wagner University of Minnesota
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota

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