D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 88 Citations 39,693 321 World Ranking 1184 National Ranking 709
Medicine D-index 100 Citations 36,934 295 World Ranking 3694 National Ranking 2102

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

The scientist’s investigation covers issues in Haematopoiesis, Immunology, Stem cell, Leukemia and Myeloid leukemia. His Haematopoiesis study combines topics in areas such as Progenitor cell, Antigen, Molecular biology, Precursor cell and Bone marrow. The Immunology study combines topics in areas such as Growth factor and Typing.

His Stem cell research integrates issues from Endothelial stem cell, Cellular differentiation and Adult stem cell. To a larger extent, Irwin D. Bernstein studies Internal medicine with the aim of understanding Leukemia. His work deals with themes such as Gemtuzumab ozogamicin and CD33, which intersect with Myeloid leukemia.

His most cited work include:

  • Leukocyte typing II (805 citations)
  • Efficacy and Safety of Gemtuzumab Ozogamicin in Patients With CD33-Positive Acute Myeloid Leukemia in First Relapse (733 citations)
  • Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support (646 citations)

What are the main themes of his work throughout his whole career to date?

Irwin D. Bernstein mainly focuses on Immunology, Haematopoiesis, Cell biology, Stem cell and Molecular biology. His study ties his expertise on Cancer research together with the subject of Immunology. His Haematopoiesis research is multidisciplinary, relying on both Progenitor cell, CD34, Stromal cell and Transplantation.

His Cell biology research is multidisciplinary, incorporating elements of Embryonic stem cell, Induced pluripotent stem cell and Cellular differentiation. Irwin D. Bernstein interconnects Cell culture, Precursor cell, B cell and Adult stem cell in the investigation of issues within Stem cell. His work in Myeloid leukemia tackles topics such as Oncology which are related to areas like Leukemia, Gemtuzumab ozogamicin and Cancer.

He most often published in these fields:

  • Immunology (47.03%)
  • Haematopoiesis (41.57%)
  • Cell biology (40.14%)

What were the highlights of his more recent work (between 2011-2021)?

  • Cell biology (40.14%)
  • Haematopoiesis (41.57%)
  • Progenitor cell (34.20%)

In recent papers he was focusing on the following fields of study:

Irwin D. Bernstein mainly investigates Cell biology, Haematopoiesis, Progenitor cell, Stem cell and Embryonic stem cell. His Cell biology study combines topics from a wide range of disciplines, such as Immunology, Cellular differentiation and Transplantation. Irwin D. Bernstein studies Bone marrow, a branch of Immunology.

He has included themes like Endothelial stem cell, Ex vivo, Cancer research, Cord blood and CD34 in his Progenitor cell study. His Cancer research research incorporates elements of Acute promyelocytic leukemia and Gemtuzumab ozogamicin, CD33. His work on Cancer stem cell is typically connected to CXCR4 as part of general Stem cell study, connecting several disciplines of science.

Between 2011 and 2021, his most popular works were:

  • SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML (297 citations)
  • SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML (297 citations)
  • Acute myeloid leukemia stem cells and CD33-targeted immunotherapy (200 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Immune system

Irwin D. Bernstein mainly investigates Cell biology, Stem cell, Immunology, Embryonic stem cell and Cellular differentiation. His research integrates issues of Molecular biology, Stromal cell, Induced pluripotent stem cell and Mesoderm in his study of Cell biology. His study in Stem cell is interdisciplinary in nature, drawing from both Bone Marrow Donation and Adult stem cell.

His studies in Immunology integrate themes in fields like Cell culture, Cancer research and Rett syndrome. The concepts of his Cancer research study are interwoven with issues in Homeobox and Gemtuzumab ozogamicin, CD33. His studies deal with areas such as Endothelial stem cell, Mesonephros, Transplantation and Progenitor cell as well as Haematopoiesis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Leukocyte typing II

Ellis L. Reinherz;Barton F. Haynes;Lee M. Nadler;Irwin D. Bernstein.
(1986)

1274 Citations

Efficacy and Safety of Gemtuzumab Ozogamicin in Patients With CD33-Positive Acute Myeloid Leukemia in First Relapse

Eric L. Sievers;Richard A. Larson;Edward A. Stadtmauer;Elihu Estey.
Journal of Clinical Oncology (2001)

1103 Citations

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

Colleen Delaney;Shelly Heimfeld;Carolyn Brashem-Stein;Howard Voorhies.
Nature Medicine (2010)

1011 Citations

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling.

Barbara Varnum-Finney;Lanwei Xu;Carolyn Brashem-Stein;Cynthia Nourigat.
Nature Medicine (2000)

984 Citations

Antigen CD34+ marrow cells engraft lethally irradiated baboons.

R J Berenson;R G Andrews;W I Bensinger;D Kalamasz.
Journal of Clinical Investigation (1988)

854 Citations

Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support

Oliver W. Press;Janet F. Eary;Frederick R. Appelbaum;Paul J. Martin.
The New England Journal of Medicine (1993)

804 Citations

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma.

RJ Berenson;WI Bensinger;RS Hill;RG Andrews.
Blood (1991)

782 Citations

Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate.

E.L. Sievers;F.R. Appelbaum;R.T. Spielberger;S.J. Forman.
Blood (1999)

695 Citations

Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.

Philip R. Hamann;Lois M. Hinman;Irwin Hollander;Carl F. Beyer.
Bioconjugate Chemistry (2002)

667 Citations

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

Jason M. Butler;Daniel J. Nolan;Eva L. Vertes;Barbara Varnum-Finney.
Cell Stem Cell (2010)

641 Citations

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