World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
39812
World Ranking
1152
National Ranking
685

Medicine

D-Index
107
Citations
40022
World Ranking
6288
National Ranking
3354

Irwin D. Bernstein publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Irwin D. Bernstein sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 385 publications — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Irwin D. Bernstein D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Irwin D. Bernstein sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 106 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Irwin D. Bernstein is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research spans multiple fields, with a significant focus on medicine and biochemistry, genetics, and molecular biology. They have contributed to molecular biology, hematology, immunology, cell biology, and genetics as subfields of study.

Their main scientific topics include:

  • Single-cell and spatial transcriptomics
  • Zebrafish biomedical research applications
  • Hematopoietic stem cell transplantation
  • Acute myeloid leukemia research
  • Immune cells in cancer
  • CAR-T cell therapy research
  • Renal and related cancers

Bernstein has published frequently in several scientific journals. The principal venues for their work include bioRxiv (Cold Spring Harbor Laboratory), Blood, Experimental Hematology, Cell Reports, and the Journal of Clinical Investigation.

Frequent coauthors collaborating with Bernstein include Brandon Hadland, Barbara Varnum-Finney, Stacey Dozono, Cynthia Nourigat-Mckay, and Shahin Rafii.

Some of the recent publications authored or co-authored by Bernstein are:

  • Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo, 2021, Cell Reports
  • Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics, 2022, Nature Communications
  • CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target, 2022, Journal of Clinical Investigation
  • NOTCH1 signaling during CD4+ T-cell activation alters transcription factor networks and enhances antigen responsiveness, 2022, Blood
  • Notch blockade overcomes endothelial cell-mediated resistance of FLT3/ITD-positive AML progenitors to AC220 treatment, 2020, Leukemia

Bernstein's work includes contributions to understanding hematopoietic stem cell biology, acute myeloid leukemia, and immune cell functions related to cancer. The research leverages advanced methodologies such as single-cell transcriptomics to investigate stem cell niches and immune interactions. Their studies on CAR-T cell therapy targets and the molecular mechanisms of leukemia highlight intersections between cancer biology and immunotherapy.

Best Publications

  • Leukocyte typing II

    Ellis L. Reinherz;Barton F. Haynes;Lee M. Nadler;Irwin D. Bernstein

  • Efficacy and Safety of Gemtuzumab Ozogamicin in Patients With CD33-Positive Acute Myeloid Leukemia in First Relapse

    Eric L. Sievers;Richard A. Larson;Edward A. Stadtmauer;Elihu Estey

  • Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

    Colleen Delaney;Shelly Heimfeld;Carolyn Brashem-Stein;Howard Voorhies

  • Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling.

    Barbara Varnum-Finney;Lanwei Xu;Carolyn Brashem-Stein;Cynthia Nourigat

  • Antigen CD34+ marrow cells engraft lethally irradiated baboons.

    R J Berenson;R G Andrews;W I Bensinger;D Kalamasz

  • Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support

    Oliver W. Press;Janet F. Eary;Frederick R. Appelbaum;Paul J. Martin

  • Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma.

    RJ Berenson;WI Bensinger;RS Hill;RG Andrews

  • Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.

    Philip R. Hamann;Lois M. Hinman;Irwin Hollander;Carl F. Beyer

  • Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

    Jason M. Butler;Daniel J. Nolan;Eva L. Vertes;Barbara Varnum-Finney

  • Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate.

    E.L. Sievers;F.R. Appelbaum;R.T. Spielberger;S.J. Forman

  • Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

    Soheil Meshinchi;William G. Woods;Derek L. Stirewalt;David A. Sweetser

  • Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties.

    R G Andrews;J W Singer;I D Bernstein

  • The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for the Growth and Survival of Sonic Hedgehog-Induced Medulloblastomas

    Andrew R. Hallahan;Joel I. Pritchard;Stacey Hansen;Mark Benson

  • Phase II trial of 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphomas

    O.W Press;O.W Press;F Appelbaum;F Appelbaum;P.J Martin;P.J Martin;D.C Matthews;D.C Matthews

  • Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors

    Robert G. Andrews;Jack W. Singer;Irwin D. Bernstein

  • SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

    May S. Kung Sutherland;Roland B. Walter;Scott C. Jeffrey;Patrick J. Burke

  • Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence

    Richard A. Larson;Eric L. Sievers;Eric L. Sievers;Edward A. Stadtmauer;Bob Löwenberg

  • Immunotherapy of Cancer: Regression of Intradermal Tumors and Prevention of Growth of Lymph Node Metastases After Intralesional Injection of Living Mycobacterium bovis

    Berton Zbar;Irwin D. Bernstein;Gerald L. Bartlett;Michael G. Hanna

  • Recombinant human stem cell factor enhances the formation of colonies by CD34+ and CD34+lin- cells, and the generation of colony-forming cell progeny from CD34+lin- cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor.

    Irwin D. Bernstein;Robert G. Andrews;Krisztina M. Zsebo

  • Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells.

    Vincent H. J. van der Velden;Jeroen G. te Marvelde;Patricia G. Hoogeveen;Irwin D. Bernstein

Frequent Co-Authors

Frederick R. Appelbaum
Frederick R. Appelbaum Fred Hutchinson Cancer Research Center
Oliver W. Press
Oliver W. Press University of Washington
Todd A. Alonzo
Todd A. Alonzo University of Southern California
Paul J. Martin
Paul J. Martin Fred Hutchinson Cancer Research Center
Jerald P. Radich
Jerald P. Radich Fred Hutchinson Cancer Research Center
Betsy A. Hirsch
Betsy A. Hirsch University of Minnesota
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital
Michael R. Loken
Michael R. Loken Fred Hutchinson Cancer Research Center
Shahin Rafii
Shahin Rafii Cornell University
William G. Woods
William G. Woods Emory University

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