Zhenkun Lou

Overview

Best Publications

• MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

  Zhenkun Lou;Katherine Minter-Dykhouse;Sonia Franco;Monica Gostissa

  806
  Citations

• FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.

  Huadong Pei;Liang Li;Brooke L. Fridley;Gregory D. Jenkins

  785
  Citations

• DBC1 is a negative regulator of SIRT1

  Ja Eun Kim;Junjie Chen;Zhenkun Lou

  701
  Citations

• USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

  Jian Yuan;Kuntian Luo;Lizhi Zhang;John C. Cheville

  667
  Citations

• MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

  Huadong Pei;Lindsey Zhang;Kuntian Luo;Yuxin Qin

  499
  Citations

• MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

  Zhenkun Lou;Katherine Minter-Dykhouse;Xianglin Wu;Junjie Chen

  475
  Citations

• CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

  Haojie Huang;Kevin M. Regan;Zhenkun Lou;Junjie Chen

  457
  Citations

• Histone H3-K56 acetylation is important for genomic stability in mammals.

  Jian Yuan;Mintie Pu;Zhiguo Zhang;Zhenkun Lou

  331
  Citations

• A c-Myc–SIRT1 feedback loop regulates cell growth and transformation

  Jian Yuan;Katherine Minter-Dykhouse;Zhenkun Lou

  317
  Citations

• H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations

  Sonia Franco;Monica Gostissa;Shan Zha;David B. Lombard

  311
  Citations

• Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

  Carlos Escande;Claudia C S Chini;Veronica Nin;Katherine Minter Dykhouse

  232
  Citations

• Sumoylation of MDC1 is important for proper DNA damage response.

  Kuntian Luo;Kuntian Luo;Haoxing Zhang;Liewei Wang;Jian Yuan;Jian Yuan

  217
  Citations

• MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

  Liming Wu;Kuntian Luo;Zhenkun Lou;Junjie Chen

  215
  Citations

• Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

  Zhenkun Lou;Claudia Christiano Silva Chini;Katherine Minter-Dykhouse;Junjie Chen

  200
  Citations

• PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

  Xinyi Tu;Bo Qin;Yong Zhang;Cheng Zhang

  198
  Citations

• A conserved NAD+ binding pocket that regulates protein-protein interactions during aging

  Jun Li;Michael S. Bonkowski;Sébastien Moniot;Dapeng Zhang

  194
  Citations

• MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

  Yosuke Ichijima;Yosuke Ichijima;Misako Ichijima;Misako Ichijima;Zhenkun Lou;André Nussenzweig

  186
  Citations

• DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

  Jia Yu;Bo Qin;Ann M. Moyer;Somaira Nowsheen

  178
  Citations

• A Balance between Positive and Negative Signals in Cytotoxic Lymphocytes Regulates the Polarization of Lipid Rafts during the Development of Cell-Mediated Killing

  Zhenkun Lou;Dragan Jevremovic;Daniel D. Billadeau;Paul J. Leibson

  162
  Citations

• BRCA1 participates in DNA decatenation.

  Zhenkun Lou;Katherine Minter-Dykhouse;Junjie Chen

  158
  Citations