2026 John F. Hancock: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	88	2663	2445	1385	1246	246	33795

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

2663

2445

1385

1246

246

33795

Biology and Biochemistry

D-Index

Citations

33795

World Ranking

2663

National Ranking

1385

Overview

John F. Hancock is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with notable contributions in Molecular Biology, Cell Biology, Physiology, Immunology, and Oncology.

The scientist's work covers a range of topics including:

Lipid Membrane Structure and Behavior
Protein Kinase Regulation and GTPase Signaling
Cellular Transport and Secretion
Endoplasmic Reticulum Stress and Disease
Protein Structure and Dynamics
Glycosylation and Glycoproteins Research
Hippo Pathway Signaling and YAP/TAZ

Recent notable publications by John F. Hancock include:

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages, 2020, Soft Matter
Glycolysis regulates KRAS plasma membrane localization and function through defined glycosphingolipids, 2023, Nature Communications
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae, 2020, The Journal of Cell Biology
Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity, 2021, Nature Communications
Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions, 2023, Molecular Cell

John F. Hancock frequently collaborates with several researchers including:

Yong Zhou
Paul Dent
Laurence Booth
Andrew Poklepovic
Ransome van der Hoeven

The scientist's work is often published in venues such as:

bioRxiv (Cold Spring Harbor Laboratory)
Proceedings of the National Academy of Sciences
Cancer Research
Nature Communications
The Journal of Cell Biology

Best Publications

All ras proteins are polyisoprenylated but only some are palmitoylated

John F. Hancock;Anthony I. Magee;Julie E. Childs;Christopher J. Marshall

2319
Citations
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

John F. Hancock;Hugh Paterson;Christopher J. Marshall

1422
Citations
Activation of Raf as a result of recruitment to the plasma membrane

David Stokoe;Susan G. Macdonald;Karen Cadwallader;Marc Symons

1277
Citations
Ras proteins: different signals from different locations

John F. Hancock

1096
Citations
Lipid rafts: contentious only from simplistic standpoints

John F Hancock

993
Citations
Direct visualization of ras proteins in spatially distinct cell surface microdomains

Ian A. Prior;Cornelia Muncke;Robert G. Parton;John F. Hancock

908
Citations
PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

Michelle M. Hill;Michele Bastiani;Robert Luetterforst;Matthew Kirkham

813
Citations
Signalling ballet in space and time

Boris N. Kholodenko;John F. Hancock;Walter Kolch

720
Citations
A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins

John F. Hancock;Karen Cadwallader;Hugh Paterson;Christopher J. Marshall

669
Citations
GTP-dependent segregation of H-ras from lipid rafts is required for biological activity.

Ian A. Prior;Angus Harding;Jun Yan;Judith Sluimer

667
Citations
Ras Isoforms Vary in Their Ability to Activate Raf-1 and Phosphoinositide 3-Kinase *

Jun Yan;Sandrine Roy;Ann Apolloni;Annette Lane

636
Citations
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

Sandrine Roy;Robert Luetterforst;Angus Harding;Ann Apolloni

606
Citations
Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis.

L. Gutierrez;A. I. Magee;C. J. Marshall;John F Hancock

600
Citations
H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway

Ann Apolloni;Ian A. Prior;Margaret Lindsay;Robert G. Parton

568
Citations
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles

Matthew Kirkham;Akikazu Fujita;Rahul Chadda;Susan J. Nixon

527
Citations
H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton.

Sarah J. Plowman;Cornelia Muncke;Robert G. Parton;John F. Hancock

526
Citations
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

Carmela Calés;John F. Hancock;Christopher J. Marshall;Alan Hall

490
Citations
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

Tianhai Tian;Angus Harding;Angus Harding;Kerry Inder;Sarah Plowman

450
Citations
Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).

John F Hancock;Karen Cadwallader;Christopher J. Marshall

399
Citations
Lipid rafts and membrane traffic.

Michael F. Hanzal-Bayer;John F. Hancock

390
Citations