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Suzanne R. Pfeffer

Suzanne R. Pfeffer

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
25534
World Ranking
3860
National Ranking
1912

Research.com Recognitions

  • 2013 - Fellow of the American Academy of Arts and Sciences
  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Suzanne R. Pfeffer is affiliated with Stanford University in the United States and has contributed extensively to research in the fields of biochemistry, genetics, and molecular biology, with significant work also in medicine. Their scientific output covers a wide array of topics including cellular transport and secretion, Parkinson's disease mechanisms and treatments, lysosomal storage disorders research, and Hedgehog signaling pathway studies.

Their research spans subfields such as molecular biology, cell biology, genetics, neurology, and physiology. Main topics frequently addressed in their work include microtubule and mitosis dynamics, genetic and kidney cyst diseases, and retinal development and disorders.

Recent publications by Suzanne R. Pfeffer demonstrate a focus on cellular mechanisms related to Parkinson's disease and signaling pathways:

  • Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain, 2021, eLife
  • Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins, 2021, Proceedings of the National Academy of Sciences
  • A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation, 2022, eLife
  • Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson's disease-linked LRRK2 kinase, 2023, eLife
  • LRRK2 phosphorylation of Rab GTPases in Parkinson's disease, 2022, FEBS Letters

Frequent collaborators in their research include Dario R. Alessi, Francesca Tonelli, Ebsy Jaimon, Herschel S. Dhekne, and Claire Y Chiang. The scientist has published multiple works in leading venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, eLife, Zenodo (CERN European Organization for Nuclear Research), and Life Science Alliance.

Suzanne R. Pfeffer's scientific achievements have been recognized through fellowships in prominent academic societies. They were named a Fellow of the American Academy of Arts and Sciences in 2013 and a Fellow of the American Association for the Advancement of Science (AAAS) in 1992.

Best Publications

  • NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

    Osman Nidai Ozes;Lindsey D. Mayo;Jason A. Gustin;Susan R. Pfeffer

  • Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi.

    Suzanne R. Pfeffer;James E. Rothman

  • Rab9 functions in transport between late endosomes and the trans Golgi network.

    D Lombardi;Thierry Soldati;M A Riederer;Y Goda

  • Rab GTPases: specifying and deciphering organelle identity and function

    Suzanne R Pfeffer

  • Targeting Rab GTPases to distinct membrane compartments.

    Suzanne Pfeffer;Dikran Aivazian

  • Transport-vesicle targeting: tethers before SNAREs.

    Suzanne R. Pfeffer

  • TIP47: A Cargo Selection Device for Mannose 6-Phosphate Receptor Trafficking

    Elva D Diaz;Suzanne R. Pfeffer

  • A single receptor binds both insulin-like growth factor II and mannose-6-phosphate.

    Richard G. Macdonald;Suzanne R. Pfeffer;Lisa Coussens;Mark A. Tepper

  • Rab GTPases: master regulators of membrane trafficking

    Suzanne R. Pfeffer

  • Rab GTPases, Directors of Vesicle Docking

    Frauke Schimmöller;Iris Simon;Suzanne R. Pfeffer

  • Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis

    Martin Steger;Federico Diez;Herschel S Dhekne;Pawel Lis

  • Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network

    Markus A. Riederer;Thierry Soldati;Allan D. Shapiro;Joseph Lin

  • Ebola virus entry requires the host-programmed recognition of an intracellular receptor

    Emily Happy Miller;Gregor Obernosterer;Matthijs Raaben;Andrew S Herbert

  • Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells

    Pierre Barbero;Lenka Bittova;Suzanne R. Pfeffer

  • Role of Rab9 GTPase in Facilitating Receptor Recruitment by TIP47

    Kate S. Carroll;John Hanna;Iris Simon;Jeff Krise

  • Rab GTPases: master regulators that establish the secretory and endocytic pathways

    Suzanne R. Pfeffer

  • Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex.

    I Corthésy-Theulaz;A Pauloin;S R Pfeffer

  • GTP-binding proteins in intracellular transport.

    Suzanne R. Pfeffer

  • Rab GTPase regulation of membrane identity.

    Suzanne R Pfeffer

  • Yip3 catalyses the dissociation of endosomal Rab-GDI complexes.

    Ulf Sivars;Dikran Aivazian;Suzanne R. Pfeffer

Frequent Co-Authors

Thierry Soldati
Thierry Soldati University of Geneva
Dario R. Alessi
Dario R. Alessi University of Dundee
James E. Rothman
James E. Rothman Yale University
David G. Lambright
David G. Lambright University of Massachusetts Chan Medical School
Francis A. Barr
Francis A. Barr University of Oxford
Benjamin S. Glick
Benjamin S. Glick University of Chicago
Joshua E. Elias
Joshua E. Elias Stanford University
Axel Knebel
Axel Knebel University of Dundee
Kate S. Carroll
Kate S. Carroll Scripps Research Institute
Jeffrey S. Glenn
Jeffrey S. Glenn Stanford University

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