David G. Lambright

Overview

Best Publications

• The 2.0 Å crystal structure of a heterotrimeric G protein

  David G. Lambright;John Sondek;Andrew Bohm;Nikolai P. Skiba

  1553
  Citations

• Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

  John Sondek;Andrew Bohm;David G. Lambright;David G. Lambright;Heidi E. Hamm

  1097
  Citations

• Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.

  David G. Lambright;Joseph P. Noel;Joseph P. Noel;Heidi E. Hamm;Paul B. Sigler

  861
  Citations

• GTPase Mechanism of Gproteins From the 1.7-A Crystal Structure of Transducin alpha-GDP-AIF-4

  John Sondek;David G. Lambright;Joseph P. Noel;Heidi E. Hamm;Heidi E. Hamm

  818
  Citations

• Rab GEFs and GAPs.

  Francis Barr;David G Lambright

  508
  Citations

• The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor.

  Takahiro Murata;Anna Delprato;Alyssa Ingmundson;Derek K Toomre

  420
  Citations

• Legionella pneumophila proteins that regulate Rab1 membrane cycling

  Alyssa Ingmundson;Anna Delprato;David G. Lambright;Craig R. Roy

  401
  Citations

• TBC-domain GAPs for rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism

  Xiaojing Pan;Sudharshan Eathiraj;Mary Munson;David G. Lambright

  396
  Citations

• Structural Basis of 3-Phosphoinositide Recognition by Pleckstrin Homology Domains

  Susan E. Lietzke;Sahana Bose;Thomas Charles Cronin;Jes K. Klarlund

  376
  Citations

• Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.

  Sudharshan Eathiraj;Xiaojing Pan;Christopher J. Ritacco;Christopher J. Ritacco;David G. Lambright

  317
  Citations

• Multivalent endosome targeting by homodimeric EEA1.

  John J. Dumas;Eric Lee Merithew;Eathiraj Sudharshan;Deepa Rajamani

  316
  Citations

• The FYVE Domain of Early Endosome Antigen 1 Is Required for Both Phosphatidylinositol 3-Phosphate and Rab5 Binding CRITICAL ROLE OF THIS DUAL INTERACTION FOR ENDOSOMAL LOCALIZATION

  Deirdre C. Lawe;Varsha Patki;Robin A. Heller-Harrison;David G. Lambright

  309
  Citations

• Membrane recognition and targeting by lipid-binding domains.

  Jonathan P. DiNitto;Thomas Charles Cronin;David G. Lambright

  235
  Citations

• Membrane and juxtamembrane targeting by PH and PTB domains.

  Jonathan P DiNitto;David G Lambright

  205
  Citations

• Sequential Roles for Phosphatidylinositol 3-Phosphate and Rab5 in Tethering and Fusion of Early Endosomes via Their Interaction with EEA1

  Deirdre C. Lawe;Anil Chawla;Eric Lee Merithew;John J. Dumas

  203
  Citations

• Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.

  Anna M. Delprato;Eric Lee Merithew;David G. Lambright

  201
  Citations

• MAP Kinase Signaling Specificity

  Claire R. Weston;David G. Lambright;Roger J. Davis

  197
  Citations

• Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

  Jonathan P. DiNitto;Anna M. Delprato;Meng-Tse Gabe Lee;Thomas Charles Cronin

  179
  Citations

• Structural Mechanisms for Regulation of Membrane Traffic by Rab GTPases

  Meng-Tse Gabe Lee;Ashwini Mishra;David G. Lambright

  172
  Citations

• Crystal structure of a G-protein βγ dimer at 2.1 Å resolution

  John Sondek;Andrew Bohm;David G. Lambright;David G. Lambright;Heidi E. Hamm

  124
  Citations