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Biology and Biochemistry

D-Index
64
Citations
15692
World Ranking
9608
National Ranking
4242

Overview

Silvia Corvera is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research predominantly situates within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on physiology, molecular biology, and epidemiology. They have contributed extensively to studies related to adipose tissue and metabolism, adipokines, inflammation, metabolic diseases, and related cardiovascular conditions.

The prominence of adipose tissue in Corvera's work is reflected in the main topics addressed, including:

  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular Disease and Adiposity
  • RNA Research and Splicing
  • Lipid metabolism and biosynthesis
  • Mesenchymal stem cell research
  • Cancer-related molecular mechanisms research

The scientist's publication record features papers in well-regarded journals, with a notable presence in bioRxiv (Cold Spring Harbor Laboratory) and Nature Metabolism among other venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Metabolism
  • Annual Review of Physiology
  • Science Translational Medicine
  • Angiogenesis

A selection of recent papers authored or co-authored by Silvia Corvera includes:

  • "Cellular Heterogeneity in Adipose Tissues," 2021, Annual Review of Physiology
  • "Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473," 2020, Nature Metabolism
  • "PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans," 2020, Science Translational Medicine
  • "Angiogenesis in adipose tissue and obesity," 2022, Angiogenesis
  • "CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease," 2021, Nature Communications

Collaborations are a significant aspect of Corvera's work, with frequent co-authors who have contributed to multiple publications. These include:

  • Tiffany DeSouza
  • Zinger Yang
  • Anand Desai
  • Javier Solivan-Rivera
  • Qin Yang

Best Publications

  • Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone

    Leanne Wilson-Fritch;Sarah M. Nicoloro;My T. Chouinard;Mitchell A. Lazar

  • SIGNALING MECHANISMS THAT REGULATE GLUCOSE TRANSPORT

    Michael P. Czech;Silvia Corvera

  • Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

    Rutilio A. Fratti;Jonathan M. Backer;Jean Gruenberg;Silvia Corvera

  • The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

    Mary Elizabeth Patti;Silvia Corvera

  • What causes the insulin resistance underlying obesity

    Olga T. Hardy;Michael P. Czech;Silvia Corvera

  • Mitochondrial Biogenesis and Remodeling during Adipogenesis and in Response to the Insulin Sensitizer Rosiglitazone

    Leanne Wilson-Fritch;Alison Burkart;Gregory Bell;Karen Mendelson

  • Cidea is associated with lipid droplets and insulin sensitivity in humans

    Vishwajeet Puri;Srijana Ranjit;Silvana Konda;Sarah M. C. Nicoloro

  • The Vascular Endothelium of the Adipose Tissue Gives Rise to Both White and Brown Fat Cells

    Khanh-Van Tran;Olga Gealekman;Andrea Frontini;Maria Cristina Zingaretti

  • Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

    Olga Gealekman;Nina Guseva;Celia Hartigan;Sarah Apotheker

  • TGFβ receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

    Susan J. Hayes;Anil Chawla;Silvia Corvera

  • Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites

    Marguerite Joly;Andrius Kazlauskas;Fredric S. Fay;Silvia Corvera

  • A functional PtdIns(3)P-binding motif

    Varsha Patki;Deirdre C. Lawe;Silvia Corvera;Joseph V. Virbasius

  • Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice

    So Yun Min;Jamie Kady;Minwoo Nam;Raziel Rojas-Rodriguez

  • Multivalent endosome targeting by homodimeric EEA1.

    John J. Dumas;Eric Lee Merithew;Eathiraj Sudharshan;Deepa Rajamani

  • The FYVE Domain of Early Endosome Antigen 1 Is Required for Both Phosphatidylinositol 3-Phosphate and Rab5 Binding CRITICAL ROLE OF THIS DUAL INTERACTION FOR ENDOSOMAL LOCALIZATION

    Deirdre C. Lawe;Varsha Patki;Robin A. Heller-Harrison;David G. Lambright

  • Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane.

    R J Davis;S Corvera;M P Czech

  • Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase

    Varsha Patki;Joseph V. Virbasius;William S. Lane;Ban-Hock Toh

  • Phosphoinositides in membrane traffic.

    Silvia Corvera;Antonello D'Arrigo;Harald Alfred Stenmark

  • Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

    Silvia Corvera;Michael P Czech

  • Adipose tissue angiogenesis: Impact on obesity and type-2 diabetes ☆

    Silvia Corvera;Olga Gealekman

Frequent Co-Authors

Michael P. Czech
Michael P. Czech University of Massachusetts Chan Medical School
Kevin E. Fogarty
Kevin E. Fogarty University of Massachusetts Chan Medical School
David G. Lambright
David G. Lambright University of Massachusetts Chan Medical School
Saverio Cinti
Saverio Cinti Marche Polytechnic University
John D. Leszyk
John D. Leszyk University of Massachusetts Chan Medical School
Roger J. Davis
Roger J. Davis University of Massachusetts Chan Medical School
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Jason K. Kim
Jason K. Kim University of Massachusetts Chan Medical School
Daryl A. Scott
Daryl A. Scott Baylor College of Medicine
Scot A. Wolfe
Scot A. Wolfe University of Massachusetts Chan Medical School

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