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John Sondek

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
16853
World Ranking
8181
National Ranking
3698

John Sondek publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John Sondek sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 157 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John Sondek D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John Sondek sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 67 D-Index — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John Sondek is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research is primarily situated within the fields of Biochemistry, Genetics, and Molecular Biology, with a focus on various subfields including Molecular Biology, Cell Biology, Physiology, Immunology, and Genetics. Their work addresses several key scientific topics:

  • Protein Kinase Regulation and GTPase Signaling
  • Alzheimer's disease research and treatments
  • Mitochondrial Function and Pathology
  • Amino Acid Enzymes and Metabolism
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cell Adhesion Molecules Research
  • Cellular transport and secretion

The scientist has published extensively, with 87 publications in related fields, predominantly through UNC Libraries. Other frequent venues include bioRxiv (Cold Spring Harbor Laboratory), OPAL (Open@LaTrobe) at La Trobe University, Journal of Biological Chemistry, and Immunity.

Recent publications by John Sondek include:

  • Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease, 2023, Immunity
  • Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis, 2020, Nature Chemical Biology
  • Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes, 2022, eLife
  • A High-Throughput Assay to Identify Allosteric Inhibitors of the PLC-γ Isozymes Operating at Membranes, 2020, Biochemistry
  • Designer proteins that competitively inhibit Gαq by targeting its effector site, 2021, Journal of Biological Chemistry

Frequent collaborators in John Sondek's work include Nicole Hajicek, T. Kendall Harden, Qisheng Zhang, Kent L. Rossman, and Edhriz Siraliev-Perez. These coauthor relationships reflect sustained research partnerships contributing to the scientific output.

Best Publications

  • GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

    Kent L. Rossman;Channing J. Der;John Sondek

  • The 2.0 Å crystal structure of a heterotrimeric G protein

    David G. Lambright;John Sondek;Andrew Bohm;Nikolai P. Skiba

  • Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

    John Sondek;Andrew Bohm;David G. Lambright;David G. Lambright;Heidi E. Hamm

  • GTPase Mechanism of Gproteins From the 1.7-A Crystal Structure of Transducin alpha-GDP-AIF-4

    John Sondek;David G. Lambright;Joseph P. Noel;Heidi E. Hamm;Heidi E. Hamm

  • Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.

    David K. Worthylake;Kent L. Rossman;John Sondek

  • Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

    John M. Lambert;Que T. Lambert;Gary W. Reuther;Angeliki Malliri

  • The experimental power of FR900359 to study Gq-regulated biological processes

    Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  • The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation

    Han Suk Kim;Darrell Desveaux;Alex U. Singer;Priyesh Patel

  • A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

    Kent L. Rossman;David K. Worthylake;Jason T. Snyder;David P. Siderovski

  • Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

    Randall J. Kimple;Michelle E. Kimple;Laurie Betts;John E Sondek

  • STRUCTURAL BASIS FOR THE SELECTIVE ACTIVATION OF RHO GTPASES BY DBL EXCHANGE FACTORS

    Jason T Snyder;David K Worthylake;Kent L Rossman;Laurie Betts

  • Kinetic Scaffolding Mediated by a Phospholipase C–β and Gq Signaling Complex

    Gary L. Waldo;Tiffany K. Ricks;Stephanie N. Hicks;Matthew L. Cheever

  • Overview of Affinity Tags for Protein Purification

    Michelle E. Kimple;John Sondek

  • Phagocytosis of Apoptotic Cells Is Regulated by a UNC-73/TRIO-MIG-2/RhoG Signaling Module and Armadillo Repeats of CED-12/ELMO

    Colin D. DeBakker;Lisa B. Haney;Jason M. Kinchen;Cynthia Grimsley

  • The phospholipase C isozymes and their regulation.

    Aurelie Gresset;John Sondek;T. Kendall Harden

  • General and Versatile Autoinhibition of PLC Isozymes

    Stephanie N. Hicks;Mark R. Jezyk;Svetlana Gershburg;Jason P. Seifert

  • Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

    Anurag Singh;Antoine E Karnoub;Todd R Palmby;Ernst Lengyel

  • Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton

    Marco A. Salazar;Adam V. Kwiatkowski;Lorenzo Pellegrini;Gianluca Cestra

  • REGULATION OF PHOSPHOLIPASE C ISOZYMES BY RAS SUPERFAMILY GTPASES

    T. Kendall Harden;John E Sondek

  • Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding.

    John Sondek;David P. Siderovski

Frequent Co-Authors

T. Kendall Harden
T. Kendall Harden University of North Carolina at Chapel Hill
David P. Siderovski
David P. Siderovski West Virginia University
Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
David R Shortle
David R Shortle Johns Hopkins University School of Medicine
Jeffery L. Dangl
Jeffery L. Dangl University of North Carolina at Chapel Hill
David G. Lambright
David G. Lambright University of Massachusetts Chan Medical School
Heidi E. Hamm
Heidi E. Hamm Vanderbilt University
Klaus M. Hahn
Klaus M. Hahn University of North Carolina at Chapel Hill
Gaudenz Danuser
Gaudenz Danuser The University of Texas Southwestern Medical Center
Darrell Desveaux
Darrell Desveaux University of Toronto

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Best Scientists Citing John Sondek

David P. Siderovski

David P. Siderovski

West Virginia University

Publications: 60

Heidi E. Hamm

Heidi E. Hamm

Vanderbilt University

Publications: 58

Channing J. Der

Channing J. Der

University of North Carolina at Chapel Hill

Publications: 53

Alan V. Smrcka

Alan V. Smrcka

University of Michigan–Ann Arbor

Publications: 47

Evi Kostenis

Evi Kostenis

University of Bonn

Publications: 42

Asuka Inoue

Asuka Inoue

Tohoku University

Publications: 41

Stephen R. Sprang

Stephen R. Sprang

University of Montana

Publications: 36

Gabriele M. König

Gabriele M. König

University of Bonn

Publications: 35

Kirill A. Martemyanov

Kirill A. Martemyanov

Scripps Research Institute

Publications: 35

Alfred Wittinghofer

Alfred Wittinghofer

Max Planck Society

Publications: 34

John J. G. Tesmer

John J. G. Tesmer

Purdue University West Lafayette

Publications: 29

Kodi S. Ravichandran

Kodi S. Ravichandran

University of Virginia

Publications: 28

Thomas Wieland

Thomas Wieland

Heidelberg University

Publications: 27

Francis S. Willard

Francis S. Willard

Eli Lilly (United States)

Publications: 26

Yi Zheng

Yi Zheng

Cincinnati Children's Hospital Medical Center

Publications: 24

Jacqueline Cherfils

Jacqueline Cherfils

École Normale Supérieure Paris-Saclay

Publications: 24

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