D-Index & Metrics Best Publications

David R Shortle

Johns Hopkins University School of Medicine
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Chemistry D-index 47 Citations 9,668 67 World Ranking 11758 National Ranking 3236

Overview

What is he best known for?

The fields of study David Shortle is best known for:

DNA
Gene
Polymerase chain reaction

In his articles, David Shortle combines various disciplines, including Gene and Locus (genetics). David Shortle integrates several fields in his works, including Locus (genetics) and Gene. DNA and Mutagenesis are two areas of study in which David Shortle engages in interdisciplinary work. As part of his studies on Mutagenesis, David Shortle frequently links adjacent subjects like Mutant. His multidisciplinary approach integrates Mutant and Genetics in his work. Many of his studies on Genetics involve topics that are commonly interrelated, such as Saccharomyces cerevisiae. His work often combines Saccharomyces cerevisiae and Yeast studies. He connects Yeast with DNA in his study. He integrates Plasmid with Molecular cloning in his research.

His most cited work include:

DENATURED STATES OF PROTEINS (825 citations)
Lethal Disruption of the Yeast Actin Gene by Integrative DNA Transformation (291 citations)
Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome. (239 citations)

What are the main themes of his work throughout his whole career to date

David Shortle conducts interdisciplinary study in the fields of Gene and Locus (genetics) through his works. David Shortle integrates several fields in his works, including Locus (genetics) and Gene. Borrowing concepts from Computational biology, David Shortle weaves in ideas under Genetics. David Shortle conducted interdisciplinary study in his works that combined Computational biology and Genetics. Many of his studies involve connections with topics such as Random coil and Crystallography. As part of his studies on Random coil, David Shortle often connects relevant areas like Crystallography. His work in Biochemistry is not limited to one particular discipline; it also encompasses Guanidine. His Biochemistry research extends to the thematically linked field of Guanidine. David Shortle regularly ties together related areas like Nuclear magnetic resonance spectroscopy in his Stereochemistry studies.

David Shortle most often published in these fields:

Gene (62.50%)
Genetics (50.00%)
Crystallography (50.00%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Denatured States of Proteins

Ken A. Dill;David Shortle.
Annual Review of Biochemistry (1991)

1216 Citations

Persistence of Native-Like Topology in a Denatured Protein in 8 M Urea

David Shortle;Michael S. Ackerman.
Science (2001)

835 Citations

Strategies and applications of in vitro mutagenesis.

David Botstein;David Shortle.
Science (1985)

737 Citations

The denatured state (the other half of the folding equation) and its role in protein stability.

David Shortle.
The FASEB Journal (1996)

580 Citations

Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease

David Shortle;Wesley E. Stites;Alan K. Meeker.
Biochemistry (1990)

524 Citations

Characterization of long-range structure in the denatured state of staphylococcal nuclease. I. Paramagnetic relaxation enhancement by nitroxide spin labels.

Joel R. Gillespie;David Shortle.
Journal of Molecular Biology (1997)

386 Citations

Characterization of long-range structure in the denatured state of staphylococcal nuclease. II. Distance restraints from paramagnetic relaxation and calculation of an ensemble of structures.

Joel R. Gillespie;David Shortle.
Journal of Molecular Biology (1997)

384 Citations

Mutant forms of staphylococcal nuclease with altered patterns of guanidine hydrochloride and urea denaturation.

David Shortle;Alan K. Meeker.
Proteins (1986)

359 Citations

Residual structure in large fragments of staphylococcal nuclease: effects of amino acid substitutions.

David Shortle;Alan K. Meeker.
Biochemistry (1989)

329 Citations

Structural analysis of non-native states of proteins by NMR methods.

David R Shortle.
Current Opinion in Structural Biology (1996)

287 Citations

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