What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Biochemistry, G protein-coupled receptor, G protein, Cell biology and Adenylyl cyclase.
The Rhodopsin kinase and Arrestin research he does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as Argininosuccinate synthase and Glutamine amidotransferase, therefore creating a link between diverse domains of science.
His study in the field of G protein-coupled receptor kinase and Beta-Arrestins also crosses realms of Visual phototransduction.
His study of Heterotrimeric G protein is a part of G protein.
The Heterotrimeric G protein study combines topics in areas such as Pleckstrin homology domain, GTPase-activating protein and G alpha subunit.
His work deals with themes such as Moesin and Ezrin, which intersect with Cell biology.
His most cited work include:
- Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis (700 citations)
- Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS. (686 citations)
- Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gbetagamma (331 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, G protein-coupled receptor, G protein-coupled receptor kinase, Cell biology and Heterotrimeric G protein.
His study in Adenylyl cyclase, Enzyme, Gs alpha subunit, Protein structure and Cyclin-dependent kinase 9 is carried out as part of his studies in Biochemistry.
His research in G protein-coupled receptor focuses on subjects like Biophysics, which are connected to Phospholipase C.
His G protein-coupled receptor kinase research is multidisciplinary, incorporating perspectives in Kinase, Protein kinase domain, Phosphorylation and Beta adrenergic receptor kinase.
He regularly ties together related areas like Allosteric regulation in his Cell biology studies.
His Heterotrimeric G protein study integrates concerns from other disciplines, such as GTPase-activating protein and G alpha subunit.
He most often published in these fields:
- Biochemistry (53.37%)
- G protein-coupled receptor (40.93%)
- G protein-coupled receptor kinase (39.38%)
What were the highlights of his more recent work (between 2018-2021)?
- G protein-coupled receptor (40.93%)
- Cell biology (39.38%)
- G protein-coupled receptor kinase (39.38%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in G protein-coupled receptor, Cell biology, G protein-coupled receptor kinase, Kinase and Biochemistry.
His G protein-coupled receptor research is multidisciplinary, relying on both RGS Proteins, Cell signaling, Genome, Regulator of G protein signaling and Protein–protein interaction.
Cell biology is represented through his Pleckstrin homology domain, GTPase, Heterotrimeric G protein and G protein research.
His G protein-coupled receptor kinase study is associated with Receptor.
His study in Kinase is interdisciplinary in nature, drawing from both Protein kinase domain and Beta adrenergic receptor kinase.
Specifically, his work in Biochemistry is concerned with the study of Lecithin—cholesterol acyltransferase.
Between 2018 and 2021, his most popular works were:
- Cryo–electron microscopy structure and analysis of the P-Rex1–Gβγ signaling scaffold (14 citations)
- Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles. (13 citations)
- Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe (9 citations)
In his most recent research, the most cited papers focused on:
John J.G. Tesmer mostly deals with G protein-coupled receptor, Biophysics, G protein, Kinase and G protein-coupled receptor kinase.
G protein-coupled receptor is a subfield of Cell biology that John J.G. Tesmer explores.
His studies deal with areas such as Cell signaling, Genome, Docking and Protein–protein interaction as well as G protein.
John J.G. Tesmer has researched Kinase in several fields, including G-Protein-Coupled Receptor Kinase 5, Beta adrenergic receptor kinase, Subfamily, Cysteine and Drug discovery.
His Beta adrenergic receptor kinase research is classified as research in Biochemistry.
His biological study spans a wide range of topics, including Transport protein, Calmodulin, Protein kinase domain and Phosphorylation.
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