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D-Index & Metrics

Chemistry

D-Index
48
Citations
6393
World Ranking
15429
National Ranking
230

Overview

Per Jemth is affiliated with Uppsala University in Sweden and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology, with significant involvement in materials chemistry, infectious diseases, cell biology, and spectroscopy as subfields.

The scientist's work covers several key topics including protein structure and dynamics, enzyme structure and function, RNA and protein synthesis mechanisms, ubiquitin and proteasome pathways, vaccines and immunoinformatics approaches, RNA research and splicing, and bacteriophages and microbial interactions.

Per Jemth has authored numerous research papers published in a variety of scientific journals. Notable recent publications include:

  • "Fuzziness and Frustration in the Energy Landscape of Protein Folding, Function, and Assembly," 2021, Accounts of Chemical Research
  • "Proteome-scale mapping of binding sites in the unstructured regions of the human proteome," 2022, Molecular Systems Biology
  • "Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities," 2021, Nature Communications
  • "Templated folding of intrinsically disordered proteins," 2020, Journal of Biological Chemistry
  • "Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs," 2023, Nature Communications

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), the Journal of Molecular Biology, Nature Communications, Protein Science, and the Journal of Biological Chemistry. These publications demonstrate a range of contributions over time to these journals.

Throughout their career, Per Jemth has collaborated regularly with several researchers, including Eva Andersson, Filip Mihalič, Ylva Ivarsson, Caroline Benz, and Leandro Simonetti. These collaborations reflect sustained research partnerships in related scientific investigations.

Best Publications

  • A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Anders Bach;Bettina H. Clausen;Magda Møller;Bente Vestergaard

  • PDZ domains: folding and binding.

    Per Jemth;Stefano Gianni

  • Single molecule unfolding and stretching of protein domains inside a solid-state nanopore by electric field

    Kevin J. Freedman;S. Raza Haq;Joshua B. Edel;Per Jemth

  • Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases.

    Rachel Hurst;Yongping Bao;Per Jemth;Bengt Mannervik

  • Distinguishing induced fit from conformational selection

    Stefano Gianni;Stefano Gianni;Jakob Dogan;Per Jemth

  • Helical Propensity in an Intrinsically Disordered Protein Accelerates Ligand Binding

    Vytautas Iešmantavičius;Jakob Dogan;Per Jemth;Kaare Teilum

  • Chemical, thermal, and electric field induced unfolding of single protein molecules studied using nanopores.

    Kevin J. Freedman;Maike Jürgens;Anmiv Prabhu;Chi Won Ahn

  • The binding mechanisms of intrinsically disordered proteins

    Jakob Dogan;Stefano Gianni;Stefano Gianni;Per Jemth

  • Biosynthetic Oligosaccharide Libraries for Identification of Protein-binding Heparan Sulfate Motifs EXPLORING THE STRUCTURAL DIVERSITY BY SCREENING FOR FIBROBLAST GROWTH FACTOR (FGF) 1 AND FGF2 BINDING

    Per Jemth;Johan Kreuger;Marion Kusche-Gullberg;Luisa Sturiale

  • Fuzziness and Frustration in the Energy Landscape of Protein Folding, Function, and Assembly.

    Stefano Gianni;María Inés Freiberger;Per Jemth;Diego U. Ferreiro

  • Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation.

    Per Jemth;Stefano Gianni;Ryan Day;Bin Li

  • The transition state structure for coupled binding and folding of disordered protein domains.

    Jakob Dogan;Xin Mu;Åke Engström;Per Jemth

  • Fibroblast growth factors share binding sites in heparan sulphate.

    Johan Kreuger;Per Jemth;Emil Sanders-Lindberg;Liat Eliahu

  • Affinity and specificity of motif-based protein-protein interactions

    Ylva Ivarsson;Per Jemth

  • Fast association and slow transitions in the interaction between two intrinsically disordered protein domains.

    Jakob Dogan;Tanja Schmidt;Xin Mu;Åke Engström

  • Demonstration of Long-Range Interactions in a PDZ Domain by NMR, Kinetics, and Protein Engineering

    Stefano Gianni;Tine Walma;Alessandro Arcovito;Nicoletta Calosci

  • Processing of macromolecular heparin by heparanase

    Feng Gong;Per Jemth;Martha L Escobar Galvis;Israel Vlodavsky

  • Reassessing a sparse energetic network within a single protein domain

    Celestine N. Chi;Lisa Elfström;Yao Shi;Tord Snäll

  • The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism.

    Stefano Gianni;Åke Engström;Mårten Larsson;Nicoletta Calosci

  • Coupled binding and folding of intrinsically disordered proteins : what can we learn from kinetics?

    Stefano Gianni;Jakob Dogan;Per Jemth

  • Renal cell carcinoma risk in type 2 von Hippel-Lindau disease correlates with defects in pVHL stability and HIF-1alpha interactions.

    K Knauth;C Bex;Per Jemth;Per Jemth;A Buchberger

Frequent Co-Authors

Stefano Gianni
Stefano Gianni Sapienza University of Rome
Åke Engström
Åke Engström Uppsala University
Bengt Mannervik
Bengt Mannervik Stockholm University
Maurizio Brunori
Maurizio Brunori Sapienza University of Rome
Joshua B. Edel
Joshua B. Edel Imperial College London
Carlo Camilloni
Carlo Camilloni University of Milan
Ulf Lindahl
Ulf Lindahl Uppsala University
Leif Andersson
Leif Andersson Texas A&M University
Alan R. Fersht
Alan R. Fersht University of Cambridge
Norman E. Davey
Norman E. Davey Institute of Cancer Research

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