What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Zinc finger nuclease, Genetics, Gene, Genome editing and Zinc finger.
His study in Zinc finger nuclease is interdisciplinary in nature, drawing from both Molecular biology, Leukemia and CD3.
His studies link DNA with Gene.
His research investigates the connection with Genome editing and areas like Induced pluripotent stem cell which intersect with concerns in Somatic cell, Phenotype, Point mutation and Isogenic human disease models.
As a part of the same scientific study, Lei Zhang usually deals with the Zinc finger, concentrating on Gene targeting and frequently concerns with Zebrafish, Mutagenesis, Danio and Mutation.
His studies deal with areas such as Transcription Activator-Like Effectors and Genome engineering as well as TAL effector.
His most cited work include:
- A TALE nuclease architecture for efficient genome editing (1772 citations)
- Genetic engineering of human pluripotent cells using TALE nucleases (1023 citations)
- Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases (950 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Genetics, Gene, Zinc finger, Zinc finger nuclease and Genome editing.
His Zinc finger study combines topics in areas such as Gene targeting, Cleavage, Promoter and Cell biology.
His research in Zinc finger nuclease intersects with topics in RNA, Molecular biology, Gene Knockout Techniques and Transgene.
His Genome editing study incorporates themes from Stem cell, Computational biology, Induced pluripotent stem cell and Locus.
As part of one scientific family, Lei Zhang deals mainly with the area of Transcription activator-like effector nuclease, narrowing it down to issues related to the TAL effector, and often Transcription Activator-Like Effectors.
The various areas that he examines in his Genome engineering study include Hematopoietic stem cell and Nuclease.
He most often published in these fields:
- Genetics (35.96%)
- Gene (32.58%)
- Zinc finger (31.46%)
What were the highlights of his more recent work (between 2015-2021)?
- Genome editing (29.21%)
- Gene (32.58%)
- Genetics (35.96%)
In recent papers he was focusing on the following fields of study:
Genome editing, Gene, Genetics, Cell biology and Zinc finger nuclease are his primary areas of study.
His work deals with themes such as Computational biology, Stem cell and Locus, which intersect with Genome editing.
His work on Histone, Phenotype and Wild type as part of general Gene research is frequently linked to Factor V, bridging the gap between disciplines.
The study incorporates disciplines such as Gene expression, Zinc finger, Endogeny, DNA-binding domain and Intron in addition to Cell biology.
His Zinc finger study is concerned with Transcription factor in general.
His Zinc finger nuclease study is related to the wider topic of Genome.
Between 2015 and 2021, his most popular works were:
- Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. (92 citations)
- Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. (52 citations)
- Mammalian interspecies substitution of immune modulatory alleles by genome editing. (51 citations)
In his most recent research, the most cited papers focused on:
Lei Zhang mainly focuses on Genome editing, Zinc finger nuclease, Genetics, Locus and Haplotype.
His Genome editing study integrates concerns from other disciplines, such as Penetrance and Gene expression.
His Zinc finger nuclease research is multidisciplinary, incorporating perspectives in RNA, Gene Knockout Techniques, Transgene and Intron.
His studies in Locus integrate themes in fields like Genome and Computational biology.
Lei Zhang has researched Haplotype in several fields, including Phenotype, Introgression, Stem cell, Induced pluripotent stem cell and African swine fever virus.
As a member of one scientific family, he mostly works in the field of Stem cell, focusing on Gene and, on occasion, Cell biology.
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