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Genetics

D-Index
44
Citations
9583
World Ranking
4253
National Ranking
142

Overview

David J. Tremethick is affiliated with the Australian National University in Australia. Their research largely falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Molecular Biology, Cancer Research, Immunology, Plant Science, and Pathology and Forensic Medicine.

Their main areas of investigation include topics related to Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, RNA modifications and cancer, Cancer-related molecular mechanisms research, RNA and protein synthesis mechanisms, Immune Cell Function and Interaction, and DNA Repair Mechanisms.

Key recent publications by David J. Tremethick feature the following works:

  • Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells, 2021, Nature Communications
  • Short Histone H2A Variants: Small in Stature but not in Function, 2020, Cells
  • Multifunctional histone variants in genome function, 2024, Nature Reviews Genetics
  • The Role of the Histone Variant H2A.Z in Metazoan Development, 2022, Journal of Developmental Biology
  • H2A.B is a cancer/testis factor involved in the activation of ribosome biogenesis in Hodgkin lymphoma, 2021, EMBO Reports

Frequent collaborators include the following coauthors:

  • Yasmin Dijkwel
  • Maxim Nekrasov
  • Renae Domaschenz
  • Xuan-Zhao Jiang
  • Tatiana Soboleva

David J. Tremethick's work has been published multiple times in several notable venues, including:

  • Nature Communications (2 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • Nature Reviews Genetics (1 publication)
  • Cells (1 publication)
  • Journal of Developmental Biology (1 publication)

Best Publications

  • New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

    Karolin Luger;Mekonnen L. Dechassa;David J. Tremethick

  • Crystal structure of a nucleosome core particle containing the variant histone H2A.Z

    Robert K. Suto;Michael J. Clarkson;David J. Tremethick;Karolin Luger

  • Histone variant H2A.Z is required for early mammalian development.

    Renate Faast;Varaporn Thonglairoam;Thomas C Schulz;Jacquie Beall

  • Higher-Order Structures of Chromatin: The Elusive 30 nm Fiber

    David J. Tremethick

  • H2A.Z Alters the Nucleosome Surface to Promote HP1α-Mediated Chromatin Fiber Folding

    Jun Y. Fan;Danny Rangasamy;Karolin Luger;David J. Tremethick

  • A unified phylogeny-based nomenclature for histone variants

    Paul B Talbert;Kami Ahmad;Geneviève Almouzni;Juan Ausió

  • The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states

    Jun Y. Fan;Faye Gordon;Karolin Luger;Jeffrey C. Hansen

  • Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development

    Danny Rangasamy;Leise Berven;Patricia Ridgway;David John Tremethick

  • RNA interference demonstrates a novel role for H2A.Z in chromosome segregation.

    Danny Rangasamy;Ian Greaves;David J Tremethick

  • A New Fluorescence Resonance Energy Transfer Approach Demonstrates That the Histone Variant H2AZ Stabilizes the Histone Octamer within the Nucleosome

    Young-Jun Park;Pamela N. Dyer;David J. Tremethick;Karolin Luger

  • The nucleosome surface regulates chromatin compaction and couples it with transcriptional repression

    Jiansheng Zhou;Jun Y Fan;Danny Rangasamy;David J Tremethick

  • Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA

    Yunhe Bao;Kasey Konesky;Young-Jun Park;Simona Rosu

  • Regions of variant histone His2AvD required for Drosophila development

    Michael John Clarkson;Julian R. E. Wells;Frank Gibson;Robert Saint

  • H2A.Z contributes to the unique 3D structure of the centromere.

    Ian K. Greaves;Danny Rangasamy;Patricia Ridgway;David J. Tremethick

  • Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

    Fátima Valdés-Mora;Jenny Z. Song;Aaron L. Statham;Dario Strbenac

  • The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

    Kimberley Bruce;Fiona A. Myers;Evangelia Mantouvalou;Pascal Lefevre

  • The X and Y Chromosomes Assemble into H2A.Z, Containing Facultative Heterochromatin, following Meiosis

    Ian K. Greaves;Danny Rangasamy;Michael Devoy;Jennifer A. Marshall Graves

  • A unique H2A histone variant occupies the transcriptional start site of active genes

    Tatiana Soboleva;Maxim Nekrasov;Anuj Pahwa;Rohan Williams;Rohan Williams

  • Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics

    Maxim Nekrasov;Jane Amrichova;Brian J Parker;Tatiana Soboleva

  • Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.

    Ming Yang;Danny Rangasamy;Klaus I. Matthaei;Ailsa J. Frew

Frequent Co-Authors

Karolin Luger
Karolin Luger University of Colorado Boulder
Christopher R. Parish
Christopher R. Parish Australian National University
Stephen J. Turner
Stephen J. Turner Monash University
Josephine Bowles
Josephine Bowles University of Queensland
Raymond Reeves
Raymond Reeves Washington State University
David A. Jans
David A. Jans Monash University
Lei Zhang
Lei Zhang Sangamo BioSciences (United States)
Daniel Vaiman
Daniel Vaiman Université Paris Cité
Edward J. Rebar
Edward J. Rebar Sangamo BioSciences (United States)
Peter Koopman
Peter Koopman University of Queensland

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