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Biology and Biochemistry

D-Index
70
Citations
15702
World Ranking
7088
National Ranking
3258

Overview

Jeffrey C. Hansen is affiliated with Colorado State University in the United States and has contributed to the field of Biochemistry, Genetics, and Molecular Biology, particularly in Molecular Biology and Plant Science. Their research focuses significantly on topics such as Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, RNA Research and Splicing, RNA modifications and cancer, Plant Molecular Biology Research, Chromosomal and Genetic Variations, and Epigenetics and DNA Methylation.

Their recent publications include:

  • Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells, 2020, Cell
  • The solid and liquid states of chromatin, 2021, Epigenetics & Chromatin
  • Fluid-like chromatin: Toward understanding the real chromatin organization present in the cell, 2020, Current Opinion in Cell Biology
  • Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Silencing the genome with linker histones, 2020, Proceedings of the National Academy of Sciences

Frequent publication venues for Hansen's work are:

  • Cell
  • Epigenetics & Chromatin
  • Current Opinion in Cell Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences

Key coauthors frequently collaborating with Hansen include:

  • Michael J. Hendzel
  • Hilmar Strickfaden
  • Thomas O. Tolsma
  • Ajit Kumar Sharma
  • D. Alan Underhill

The scope of Hansen's work encompasses a detailed understanding of chromatin states and dynamics, with a particular interest in the physical properties of chromatin such as its solid and liquid states. Their research has explored molecular mechanisms underlying chromatin organization and gene silencing processes.

Best Publications

  • Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

    Christin Tse;Takashi Sera;Alan P. Wolffe;Jeffrey C. Hansen

  • Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

    Jan Bednar;Rachel A. Horowitz;Sergei A. Grigoryev;Lenny M. Carruthers

  • Conformational Dynamics of the Chromatin Fiber in Solution: Determinants, Mechanisms, and Functions

    Jeffrey C. Hansen

  • Chromatin Compaction by Human MeCP2 ASSEMBLY OF NOVEL SECONDARY CHROMATIN STRUCTURES IN THE ABSENCE OF DNA METHYLATION

    Philippe T. Georgel;Philippe T. Georgel;Rachel A. Horowitz-Scherer;Nick Adkins;Christopher L. Woodcock

  • Structure and Function of the Core Histone N-Termini: More Than Meets the Eye†

    Jeffrey C. Hansen;Christin Tse;Alan P. Wolffe

  • The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states

    Jun Y. Fan;Faye Gordon;Karolin Luger;Jeffrey C. Hansen

  • Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)

    Mary M. Robinson;Steven J. Mcbryant;Takashi Tsukamoto;Camilo Rojas

  • Intrinsic protein disorder, amino acid composition, and histone terminal domains.

    Jeffrey C. Hansen;Xu Lu;Eric D. Ross;Robert W. Woody

  • Reversible oligonucleosome self-association: dependence on divalent cations and core histone tail domains

    Patricia M. Schwarz;Alicia Felthauser;Terace M. Fletcher;Jeffrey C. Hansen

  • Linker histones stabilize the intrinsic salt-dependent folding of nucleosomal arrays: mechanistic ramifications for higher-order chromatin folding.

    Lenny M. Carruthers;Jan Bednar;Christopher L. Woodcock;Jeffrey C. Hansen

  • Nucleosome and chromatin fiber dynamics

    Karolin Luger;Jeffrey C Hansen

  • Homogeneous reconstituted oligonucleosomes, evidence for salt-dependent folding in the absence of histone H1.

    Jeffrey C. Hansen;Juan Ausio;Valerie H. Stanik;K. E. Van Holde

  • The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure.

    Xu Lu;Matthew D Simon;Jayanth V Chodaparambil;Jeffrey C Hansen

  • The role of the nucleosome acidic patch in modulating higher order chromatin structure

    Anna A. Kalashnikova;Mary E. Porter-Goff;Uma M. Muthurajan;Karolin Luger

  • Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells.

    Hilmar Strickfaden;Thomas O. Tolsma;Ajit Sharma;D. Alan Underhill

  • DNA and protein determinants of nucleosome positioning on sea urchin 5S rRNA gene sequences in vitro.

    Feng Dong;J. C. Hansen;K. E. Van Holde

  • Formation and stability of higher order chromatin structures : contributions of the histone octamer

    P.M. Schwarz;J.C. Hansen

  • Malleable machines take shape in eukaryotic transcriptional regulation

    Monika Fuxreiter;Peter Tompa;István Simon;Vladimir N Uversky

  • Core Histone Tail Domains Mediate Oligonucleosome Folding and Nucleosomal DNA Organization through Distinct Molecular Mechanisms

    Terace M. Fletcher;Jeffrey C. Hansen

  • The Nucleosomal Array: Structure/Function Relationships

    Terace M. Fletcher;Jeffrey C. Hansen

Frequent Co-Authors

Karolin Luger
Karolin Luger University of Colorado Boulder
Christopher L. Woodcock
Christopher L. Woodcock University of Massachusetts Amherst
Borries Demeler
Borries Demeler University of Lethbridge
Jeffrey J. Hayes
Jeffrey J. Hayes University of Rochester Medical Center
Alan P. Wolffe
Alan P. Wolffe Sangamo BioSciences (United States)
Craig L. Peterson
Craig L. Peterson University of Massachusetts Chan Medical School
K. E. Van Holde
K. E. Van Holde Oregon State University
Michael J. Hendzel
Michael J. Hendzel University of Alberta
Ben E. Black
Ben E. Black University of Pennsylvania
Paul A. Wade
Paul A. Wade National Institutes of Health

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