Michael J. Hendzel

Overview

Best Publications

• Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation.

  M J Hendzel;Y Wei;M A Mancini;A Van Hooser

  2771
  Citations

• PARP inhibition: PARP1 and beyond

  Michèle Rouleau;Anand Patel;Michael J. Hendzel;Scott H. Kaufmann

  1565
  Citations

• Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR

  Wolfgang Fischle;Franck Dequiedt;Michael J Hendzel;Matthew G Guenther

  964
  Citations

• PARP1-dependent Kinetics of Recruitment of MRE11 and NBS1 Proteins to Multiple DNA Damage Sites

  Jean-François Haince;Darin McDonald;Amélie Rodrigue;Ugo Déry

  689
  Citations

• Rapid exchange of histone H1.1 on chromatin in living human cells

  Melody A. Lever;John P. H. Th'ng;Xuejun Sun;Michael J. Hendzel

  490
  Citations

• Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

  Jean Philippe Gagné;Maxim Isabelle;Ken Sin Lo;Sylvie Bourassa

  469
  Citations

• RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

  Frédérick A Mallette;Frédérick A Mallette;Francesca Mattiroli;Gaofeng Cui;Leah C Young

  382
  Citations

• Promyelocytic Leukemia (Pml) Nuclear Bodies Are Protein Structures That Do Not Accumulate RNA

  François-Michel Boisvert;Michael J. Hendzel;David P. Bazett-Jones

  357
  Citations

• Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts.

  D N Chadee;M J Hendzel;C P Tylipski;C D Allis

  351
  Citations

• Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents.

  Jean François Haince;Sergei Kozlov;Valina L. Dawson;Ted M. Dawson

  338
  Citations

• Human HDAC7 Histone Deacetylase Activity Is Associated with HDAC3 in Vivo

  Wolfgang Fischle;Franck Dequiedt;Maryse Fillion;Michael J. Hendzel

  325
  Citations

• A NEW FAMILY OF HUMAN HISTONE DEACETYLASES RELATED TO SACCHAROMYCES CEREVISIAE HDA1P

  Wolfgang Fischle;Stephane Emiliani;Michael J. Hendzel;Takahiro Nagase

  313
  Citations

• Nucleoplasmic β-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations

  Darin McDonald;Gustavo Carrero;Christi Andrin;Gerda de Vries

  305
  Citations

• BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

  Ismail Hassan Ismail;Christi Andrin;Darin McDonald;Michael J. Hendzel

  291
  Citations

• ATM-dependent DNA Damage-independent Mitotic Phosphorylation of H2AX in Normally Growing Mammalian Cells

  Kirk J. McManus;Michael J. Hendzel

  289
  Citations

• The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.

  Michael J. Hendzel;Melody A. Lever;Ellen Crawford;John P.H. Th'ng

  285
  Citations

• Using FRAP and mathematical modeling to determine the in vivo kinetics of nuclear proteins.

  Gustavo Carrero;Darin McDonald;Ellen Crawford;Gerda de Vries

  268
  Citations

• H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.

  John P.H. Th'ng;Rohyun Sung;Ming Ye;Michael J. Hendzel

  268
  Citations

• Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.

  Michael J. Kruhlak;Michael J. Hendzel;Wolfgang Fischle;Nicholas R. Bertos

  253
  Citations

• Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments.

  Michael J. Kruhlak;Melody A. Lever;Wolfgang Fischle;Eric Verdin

  252
  Citations