What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Molecular biology, Cell biology, Histone, DNA damage and Chromatin.
His research in Molecular biology intersects with topics in Processivity, STIM1 and Genome instability.
The various areas that Michael J. Kruhlak examines in his Cell biology study include CTLA-4, Cell membrane and Antigen.
In general Histone study, his work on Histone methyltransferase and Histone H2A often relates to the realm of Histone code, thereby connecting several areas of interest.
His DNA damage research entails a greater understanding of DNA.
His Chromatin research is multidisciplinary, relying on both Cell cycle and MDC1.
His most cited work include:
- Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks (847 citations)
- Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks (425 citations)
- Inhibition of the intestinal glucose transporter GLUT2 by flavonoids (299 citations)
What are the main themes of his work throughout his whole career to date?
Michael J. Kruhlak spends much of his time researching Cell biology, Molecular biology, Chromatin, Cancer research and Immunology.
His work carried out in the field of Cell biology brings together such families of science as DNA, DNA damage, Ezrin, Radixin and Chromatin remodeling.
His Molecular biology research is multidisciplinary, incorporating elements of RNA, Ataxia-telangiectasia, Lytic cycle and Viral replication.
Michael J. Kruhlak has researched Chromatin in several fields, including Histone, Transcription factor and Microscopy.
His Cancer research study deals with Immunotherapy intersecting with Induced pluripotent stem cell.
In his study, Macrophage is inextricably linked to Microbiology, which falls within the broad field of Immunology.
He most often published in these fields:
- Cell biology (47.22%)
- Molecular biology (26.85%)
- Chromatin (17.59%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (47.22%)
- Cancer research (17.59%)
- Organelle (2.78%)
In recent papers he was focusing on the following fields of study:
Michael J. Kruhlak mainly focuses on Cell biology, Cancer research, Organelle, Transcription factor and Chromatin.
His Cell biology research includes elements of Sarcomere organization, RAD51, Homologous recombination, Mutation and Gene silencing.
Michael J. Kruhlak combines subjects such as DNA damage, Ubiquitin, Synthetic lethality and Effector with his study of Homologous recombination.
The study incorporates disciplines such as Tumor necrosis factor alpha, Chromophobe cell, Clear cell, PD-L1 and Adenocarcinoma in addition to Cancer research.
His Organelle research includes themes of Golgi apparatus, Endoplasmic reticulum and Cell cycle, CEP63, Centrosome.
His Transcription factor study integrates concerns from other disciplines, such as Promoter, Transcription and Activator.
Between 2018 and 2021, his most popular works were:
- T cell stemness and dysfunction in tumors are triggered by a common mechanism. (127 citations)
- 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination (36 citations)
- Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques. (36 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cell biology, Chromatin, Transcription, Activator and Gene.
He has included themes like RAD51 and Homologous recombination in his Cell biology study.
The concepts of his RAD51 study are interwoven with issues in Ubiquitin, Ubiquitin ligase, Synthetic lethality, PARP inhibitor and Haploinsufficiency.
His studies in Homologous recombination integrate themes in fields like Mutation and DNA damage, Genome instability.
His Transcription study incorporates themes from Promoter, Regulation of gene expression, Transcription factor and Genome.
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