World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
15250
World Ranking
9135
National Ranking
4057

Michael J. Kruhlak publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Michael J. Kruhlak sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 133 publications — 18th percentile

18% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Michael J. Kruhlak D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Michael J. Kruhlak sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 65 D-Index — 55th percentile

55% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Michael J. Kruhlak is affiliated with the National Institutes of Health in the United States. Their research primarily spans the areas of biochemistry, genetics, and molecular biology, with a notable focus on molecular biology, oncology, immunology, cell biology, and genetics. The scientist has contributed extensively to topics such as RNA research and splicing, pluripotent stem cells research, CRISPR and genetic engineering, RNA modifications and cancer, epigenetics and DNA methylation, DNA repair mechanisms, and genetics and neurodevelopmental disorders.

Kruhlak's recent scholarly output includes several publications with varying citation counts, indicating an active engagement in multiple research domains. Notable papers include:

  • "ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer" (2021, Nature Communications)
  • "Active DNA demethylation promotes cell fate specification and the DNA damage response" (2022, Science)
  • "IDH1 mutations induce organelle defects via dysregulated phospholipids" (2021, Nature Communications)
  • "CTCF is a barrier for 2C-like reprogramming" (2021, Nature Communications)
  • "Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response" (2021, Nature Communications)

The scientist has frequently published in several journals, particularly:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • Thyroid
  • Nucleic Acids Research

Collaboration plays a considerable role in their work. Key frequent co-authors include:

  • Andy D. Tran
  • Raj Chari
  • Sergio Ruiz
  • Steven D. Cappell
  • Sheue-yann Cheng

The range of research areas and topics, supported by evidence from the scientist's publication and collaboration record, portrays a career focused on understanding complex biological processes at molecular and genetic levels. This includes ongoing investigation into mechanisms of cancer biology, stem cell behavior, epigenetic regulation, and the molecular underpinnings guiding DNA repair and cell fate decisions.

Best Publications

  • Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

    Arkady Celeste;Oscar Fernandez-Capetillo;Michael J. Kruhlak;Duane R. Pilch

  • Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

    Michael J. Kruhlak;Arkady Celeste;Graham Dellaire;Oscar Fernandez-Capetillo

  • Inhibition of the intestinal glucose transporter GLUT2 by flavonoids

    Oran Kwon;Peter Eck;Shenglin Chen;Christopher P. Corpe

  • T cell stemness and dysfunction in tumors are triggered by a common mechanism.

    Suman Kumar Vodnala;Robert Eil;Rigel J. Kishton;Madhusudhanan Sukumar

  • TLR9 Is Localized in the Endoplasmic Reticulum Prior to Stimulation

    Cynthia A. Leifer;Margaret N. Kennedy;Alessandra Mazzoni;ChangWoo Lee

  • Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals.

    Jung-Ae Kim;Michael Kruhlak;Farokh Dotiwala;André Nussenzweig

  • 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Elsa Callen;Michela Di Virgilio;Michael J. Kruhlak;Maria Nieto-Soler

  • 53BP1 facilitates long-range DNA end-joining during V(D)J recombination

    Simone Difilippantonio;Eric Gapud;Nancy Wong;Ching Yu Huang

  • A multiprotein supercomplex controlling oncogenic signalling in lymphoma

    James D. Phelan;Ryan M. Young;Daniel E. Webster;Sandrine Roulland;Sandrine Roulland

  • Regulation of Histone Deacetylase 4 by Binding of 14-3-3 Proteins

    Audrey H. Wang;Michael J. Kruhlak;Jiong Wu;Nicholas R. Bertos

  • The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks.

    Michael Kruhlak;Elizabeth E. Crouch;Marika Orlov;Carolina Montaño

  • Cooperative Epigenetic Modulation by Cancer Amplicon Genes

    Lixin Rui;N. C.Tolga Emre;Michael J. Kruhlak;Hye Jung Chung

  • Basis of CTLA-4 function in regulatory and conventional CD4+ T cells

    Xuguang Tai;François Van Laethem;Leonid Pobezinsky;Terry Guinter

  • Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

    Simone Difilippantonio;Arkady Celeste;Oscar Fernandez-Capetillo;Hua-Tang Chen

  • Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.

    Michael J. Kruhlak;Michael J. Hendzel;Wolfgang Fischle;Nicholas R. Bertos

  • Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments.

    Michael J. Kruhlak;Melody A. Lever;Wolfgang Fischle;Eric Verdin

  • Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma

    Laurence Lamy;Vu N. Ngo;N.C. Tolga Emre;Arthur L. Shaffer

  • Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients

    Jean-Philippe Herbeuval;Jakob Nilsson;Adriano Boasso;Andrew W. Hardy

  • A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.

    Simran Khurana;Michael J. Kruhlak;Jeongkyu Kim;Andy D. Tran

  • Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis

    Harald F Langer;Eun Young Choi;Eun Young Choi;Eun Young Choi;Hong Zhou;Rebecca Schleicher

Frequent Co-Authors

André Nussenzweig
André Nussenzweig National Institutes of Health
Zhi-Ming Zheng
Zhi-Ming Zheng National Institutes of Health
David P. Bazett-Jones
David P. Bazett-Jones University of Calgary
Michael J. Hendzel
Michael J. Hendzel University of Alberta
Elsa Callen
Elsa Callen National Institutes of Health
Nicholas P. Restifo
Nicholas P. Restifo National Institutes of Health
Stephen Shaw
Stephen Shaw National Institutes of Health
Louis M. Staudt
Louis M. Staudt National Institutes of Health
Lionel Feigenbaum
Lionel Feigenbaum Science Applications International Corporation (United States)
Eun-Young Choi
Eun-Young Choi Vanderbilt University

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