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Triantafyllos Chavakis

Triantafyllos Chavakis

D-Index & Metrics

Immunology

D-Index
91
Citations
28823
World Ranking
1043
National Ranking
65

Medicine

D-Index
91
Citations
28916
World Ranking
11804
National Ranking
642

Overview

Triantafyllos Chavakis is affiliated with TU Dresden in Germany and specializes in various areas within biomedical sciences. Their research primarily encompasses Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with a particular focus on the fields of Immunology, Molecular Biology, and Genetics.

The scientist's work spans several subfields, including Immunology, Molecular Biology, Genetics, Epidemiology, and Cancer Research. The main topics covered in their research are diverse and include immune responses and vaccinations, immune cells in cancer, diabetes and associated disorders, liver disease diagnosis and treatment, cancer, hypoxia, and metabolism, immune response and inflammation, as well as epigenetics and DNA methylation.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, Blood, Journal of Clinical Investigation, and the International Journal of Molecular Sciences. This indicates a broad engagement with both preprint and peer-reviewed journals across notable biomedical disciplines.

The scientist has collaborated extensively with a number of co-authors, most frequently with George Hajishengallis, Vasileia Ismini Alexaki, Ben Wielockx, Mirko Peitzsch, and Ioannis Kourtzelis. These collaborations reflect a multidisciplinary and international approach to research.

Some of the recent papers authored or co-authored by Triantafyllos Chavakis include:

  • Defining trained immunity and its role in health and disease (2020), published in Nature Reviews Immunology
  • Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities (2021), published in Nature Reviews Immunology
  • Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity (2020), published in Cell
  • Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020), published in Nature Immunology
  • Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy (2020), published in Periodontology 2000

The research topics of these papers cover immune training mechanisms, inflammation linking periodontal disease with other inflammatory conditions, anti-tumor immune responses, and the cellular and molecular basis of trained immunity and tolerance. This body of work supports a focus on both fundamental immunology and its implications in disease contexts such as cancer and chronic inflammatory disorders.

Best Publications

  • Defining trained immunity and its role in health and disease

    Mihai G. Netea;Mihai G. Netea;Jorge Domínguez-Andrés;Luis B. Barreiro;Luis B. Barreiro;Triantafyllos Chavakis;Triantafyllos Chavakis

  • Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

    George Hajishengallis;Triantafyllos Chavakis

  • Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

    Ioannis Mitroulis;Klara Ruppova;Baomei Wang;Lan Sun Chen

  • Metabolic Induction of Trained Immunity through the Mevalonate Pathway

    Siroon Bekkering;Rob J.W. Arts;Boris Novakovic;Ioannis Kourtzelis

  • The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

    Abigail Woodfin;Mathieu-Benoit Voisin;Martina Beyrau;Bartomeu Colom

  • Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.

    Lydia Kalafati;Lydia Kalafati;Ioannis Kourtzelis;Ioannis Kourtzelis;Ioannis Kourtzelis;Jonas Schulte-Schrepping;Xiaofei Li

  • Trained immunity, tolerance, priming and differentiation: distinct immunological processes.

    Maziar Divangahi;Peter Aaby;Shabaana A. Khader;Luis B. Barreiro

  • A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin.

    Valeria V Orlova;Eun Young Choi;Changping Xie;Emmanouil Chavakis

  • Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

    J Graessler;Y Qin;H Zhong;J Zhang

  • The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

    Mehmet A Eskan;Ravi Jotwani;Toshiharu Abe;Toshiharu Abe;Jindrich Chmelar

  • Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis

    Berend Isermann;Ilya A Vinnikov;Thati Madhusudhan;Stefanie Herzog

  • Leukocyte-endothelial interactions in inflammation.

    Harald F. Langer;Triantafyllos Chavakis

  • Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy.

    George Hajishengallis;Triantafyllos Chavakis;John D. Lambris

  • High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells

    Emmanouil Chavakis;Andreas Hain;Maria Vinci;Guillaume Carmona

  • Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis

    Georg F. Weber;Georg F. Weber;Benjamin G. Chousterman;Shun He;Ashley M. Fenn

  • Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.

    Eun Young Choi;Emmanouil Chavakis;Marcus A. Czabanka;Harald F. Langer

  • Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-driven Inflammatory Bone Loss

    Niki M. Moutsopoulos;Joanne Konkel;Mojgan Sarmadi;Mehmet A. Eskan

  • Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo

    Bartomeu Colom;Jennifer V. Bodkin;Martina Beyrau;Abigail Woodfin

  • Phagocytosis of Apoptotic Cells in Resolution of Inflammation.

    Ioannis Kourtzelis;George Hajishengallis;Triantafyllos Chavakis;Triantafyllos Chavakis

  • Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation.

    Triantafyllos Chavakis;Ioannis Mitroulis;Ioannis Mitroulis;Ioannis Mitroulis;George Hajishengallis

  • Regulation of integrin activity and signalling

    Carl G. Gahmberg;Susanna C. Fagerholm;Susanna M. Nurmi;Triantafyllos Chavakis

  • The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms

    Athanasios N. Athanasopoulos;Matina Economopoulou;Valeria V. Orlova;Astrid Sobke

Frequent Co-Authors

George Hajishengallis
George Hajishengallis University of Pennsylvania
Mihai G. Netea
Mihai G. Netea Radboud University
Eun-Young Choi
Eun-Young Choi Vanderbilt University
Klaus T. Preissner
Klaus T. Preissner University of Giessen
Leo A. B. Joosten
Leo A. B. Joosten Radboud University
Peter P. Nawroth
Peter P. Nawroth Heidelberg University
Sentot Santoso
Sentot Santoso University of Giessen
Esther Lutgens
Esther Lutgens Ludwig-Maximilians-Universität München
Jochen Hampe
Jochen Hampe TU Dresden

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