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Michel Aurrand-Lions

Michel Aurrand-Lions

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
9028
World Ranking
18666
National Ranking
859

Overview

Michel Aurrand-Lions is affiliated with Aix-Marseille University in France. Their research spans several interconnected domains within medicine, with notable contributions to immunology, hematology, and molecular biology. Their work engages deeply with the molecular and cellular mechanisms underlying hematologic malignancies and immune system function.

Their recent scientific output includes publications across various peer-reviewed venues, illustrating a focus on the pathophysiology and microenvironment interactions in blood cancers and immune regulation. Recent papers authored or co-authored by Michel Aurrand-Lions include:

  • "Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification" (2020, The American Journal of Human Genetics)
  • "Toward Therapeutic Targeting of Bone Marrow Leukemic Niche Protective Signals in B-Cell Acute Lymphoblastic Leukemia" (2021, Frontiers in Oncology)
  • "The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5" (2021, Blood Advances)
  • "Adhesion Molecules Involved in Stem Cell Niche Retention During Normal Haematopoiesis and in Acute Myeloid Leukaemia" (2021, Frontiers in Immunology)
  • "Chronic IL-15 Stimulation and Impaired mTOR Signaling and Metabolism in Natural Killer Cells During Acute Myeloid Leukemia" (2021, Frontiers in Immunology)

The research trajectory of Michel Aurrand-Lions underscores several main fields of study:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these, subfields often addressed include immunology, hematology, molecular biology, cell biology, and public health-related concerns. This multidisciplinary approach facilitates the study of complex diseases such as acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), focusing on the tumor microenvironment and immune cell dynamics.

Main topics of Michel Aurrand-Lions' work involve:

  • Acute Myeloid Leukemia Research
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • Acute Lymphoblastic Leukemia research
  • Ubiquitin and proteasome pathways
  • Immune cells in cancer
  • T-cell and B-cell Immunology

Michel Aurrand-Lions has frequently collaborated with several researchers, contributing to a network of co-authorships including:

  • Stéphane J.C. Mancini
  • Norbert Vey
  • Cyril Fauriat
  • Marielle Balzano
  • Adrienne Anginot

The scientist's works have appeared repeatedly in several prominent journals and venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood Advances
  • Frontiers in Immunology
  • Blood
  • The American Journal of Human Genetics

Best Publications

  • Adhesion mechanisms regulating the migration of monocytes

    Beat A Imhof;Michel Aurrand-Lions

  • Dual role of macrophages in tumor growth and angiogenesis

    Chrystelle Lamagna;Michel Aurrand-Lions;Beat A. Imhof

  • ALTERED CELLULAR PROLIFERATION AND MESODERM PATTERNING IN POLYCOMB-M33-DEFICIENT MICE

    N. Core;S. Bel;S.J. Gaunt;M. Aurrand-Lions

  • The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

    Klaus Ebnet;Michel Aurrand-Lions;Annegret Kuhn;Friedemann Kiefer

  • Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members.

    Michel Aurrand-Lions;Caroline Johnson-Leger;Cindy Wong;Louis Du Pasquier

  • Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C

    Georgia Gliki;Klaus Ebnet;Michel Aurrand-Lions;Beat A. Imhof

  • JAM-2, a Novel Immunoglobulin Superfamily Molecule, Expressed by Endothelial and Lymphatic Cells

    Michel A. Aurrand-Lions;Lidia Duncan;Christoph Ballestrem;Beat A. Imhof

  • Homing Phenotypes of Tumor-Specific CD8 T Cells Are Predetermined at the Tumor Site by Crosspresenting APCs

    Thomas Calzascia;Frédérick Masson;Wilma Di Berardino-Besson;Emmanuel Contassot

  • The parting of the endothelium: miracle, or simply a junctional affair?

    Caroline Johnson-Leger;Michel Aurrand-Lions;Beat Imhof

  • Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration

    Caroline A. Johnson-Léger;Michel Aurrand-Lions;Nicola Beltraminelli;Nicolas Fasel

  • Angiogenesis and inflammation face off

    Beat A Imhof;Michel Aurrand-Lions

  • Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding.

    A. E. Prota;J. A. Campbell;Pierre Schelling;J. C. Forrest

  • Junctional Adhesion Molecule-C Regulates the Early Influx of Leukocytes into Tissues during Inflammation

    Michel Aurrand-Lions;Chrystelle Lamagna;John P. Dangerfield;Shijun Wang

  • JAM-C regulates unidirectional monocyte transendothelial migration in inflammation

    Paul F. Bradfield;Christoph Scheiermann;Sussan Nourshargh;Christiane Ody

  • Junctional Adhesion Molecule A Serves as a Receptor for Prototype and Field-Isolate Strains of Mammalian Reovirus

    Jacquelyn A. Campbell;Pierre Schelling;J. Denise Wetzel;Elizabeth M. Johnson

  • Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis.

    Yann Parel;Michel Aurrand-Lions;Agneta Scheja;Jean-Michel Dayer

  • Vanin-1, a Novel GPI-Linked Perivascular Molecule Involved in Thymus Homing

    Michel Aurrand-Lions;Franck Galland;Hermine Bazin;Vladimir M Zakharyev

  • Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.

    Chrystelle Lamagna;Paolo Meda;Guillaume Mandicourt;James Brown

  • Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues.

    Wenyan He;Stephan Holtkamp;Sophia Martina Hergenhan;Kerstin Kraus

  • Antibody against Junctional Adhesion Molecule-C Inhibits Angiogenesis and Tumor Growth

    Chrystelle Lamagna;Kairbaan M. Hodivala-Dilke;Beat A. Imhof;Michel Aurrand-Lions

Frequent Co-Authors

Beat A. Imhof
Beat A. Imhof University of Geneva
Ralf H. Adams
Ralf H. Adams Max Planck Society
Sussan Nourshargh
Sussan Nourshargh Queen Mary University of London
Philippe Naquet
Philippe Naquet Grenoble Alpes University
Paolo Meda
Paolo Meda University of Geneva
Klaus Ebnet
Klaus Ebnet University of Münster
Norbert Vey
Norbert Vey Aix-Marseille University
Gaby Palmer
Gaby Palmer University of Geneva
Richard Reynolds
Richard Reynolds Imperial College London

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