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Immunology

D-Index
68
Citations
23270
World Ranking
2551
National Ranking
222

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Sussan Nourshargh is affiliated with Queen Mary University of London in the United Kingdom. Their research spans multiple fields, with a strong focus on biochemistry, genetics and molecular biology, medicine, and immunology and microbiology. Subfields of specialization include molecular biology, immunology, immunology and allergy, pulmonary and respiratory medicine, as well as neurology.

The scientist's work covers a variety of main topics:

  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Cell Adhesion Molecules Research
  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Immune cells in cancer
  • PARP inhibition in cancer therapy
  • Wnt/β-catenin signaling in development and cancer

Among the recent papers associated with Sussan Nourshargh are:

  • "Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage," 2021, Immunity
  • "Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation," 2021, Immunity
  • "Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice," 2020, American Journal of Respiratory and Critical Care Medicine
  • "Local microvascular leakage promotes trafficking of activated neutrophils to remote organs," 2020, Journal of Clinical Investigation
  • "Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome," 2021, Circulation

Sussan Nourshargh frequently collaborates with several co-authors, including:

  • Loïc Rolas
  • Natalia Reglero-Real
  • Anna Barkaway
  • Mathieu-Benoît Voisin
  • Matt Golding

The scientist's research has appeared in a range of publication venues, reflecting their multidisciplinary approach. Frequent venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • eLife
  • American Journal of Respiratory and Critical Care Medicine
  • Journal of Clinical Investigation

Sussan Nourshargh has been recognized as a Fellow of The Academy of Medical Sciences in the United Kingdom.

Best Publications

  • Getting to the site of inflammation: the leukocyte adhesion cascade updated

    Klaus Ley;Carlo Laudanna;Myron I. Cybulsky;Sussan Nourshargh

  • Leukocyte migration into inflamed tissues.

    Sussan Nourshargh;Ronen Alon

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • PECAM-1: A Multi-Functional Molecule in Inflammation and Vascular Biology

    Abigail Woodfin;Mathieu-Benoit Voisin;Sussan Nourshargh

  • Breaching multiple barriers : Leukocyte motility through venular walls and the interstitium

    Sussan Nourshargh;Peter L. Hordijk;Michael Sixt

  • The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

    Abigail Woodfin;Mathieu-Benoit Voisin;Martina Beyrau;Bartomeu Colom

  • Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

    Doris Proebstl;Mathieu-Benoit Voisin;Abigail Woodfin;James R. Whiteford

  • Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

    Tamara Girbl;Tchern Lenn;Lorena Perez;Loïc Rolas

  • Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo

    Mark A. Little;C. Lucy Smyth;Rashmi Yadav;Lyn Ambrose

  • Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo

    Bartomeu Colom;Jennifer V. Bodkin;Martina Beyrau;Abigail Woodfin

  • Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK.

    Lauren A. Callender;Elizabeth C. Carroll;Robert W. J. Beal;Emma S. Chambers

  • Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity.

    Martina Beyrau;Jennifer Victoria Bodkin;Sussan Nourshargh

  • Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.

    Abigail Woodfin;Mathieu-Benoit Voisin;Beat A. Imhof;Elisabetta Dejana

  • An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane

    M W Wakelin;M J Sanz;A Dewar;S M Albelda

  • Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane.

    Richard D. Thompson;Karen E. Noble;Karen E. Noble;Karen Y. Larbi;Karen Y. Larbi;Ann Dewar;Ann Dewar

  • A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.

    V B Weg;T J Williams;R R Lobb;S Nourshargh

  • Endothelial Cell Junctional Adhesion Molecules: Role and Regulation of Expression in Inflammation.

    Natalia Reglero-Real;Bartomeu Colom;Bartomeu Colom;Jennifer Victoria Bodkin;Sussan Nourshargh

  • Reverse Migration of Neutrophils: Where, When, How, and Why?

    Sussan Nourshargh;Stephen A. Renshaw;Beat A. Imhof

  • Transmigration through venular walls: a key regulator of leukocyte phenotype and function.

    Sussan Nourshargh;Federica M. Marelli-Berg

  • Recent developments and complexities in neutrophil transmigration.

    Abigail Woodfin;Mathieu-Benoit Voisin;Sussan Nourshargh

  • Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis.

    Peter J. Norsworthy;Liliane Fossati-Jimack;Josefina Cortes-Hernandez;Philip R. Taylor

  • The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues

    Sussan Nourshargh;Fritz Krombach;Elisabetta Dejana

Frequent Co-Authors

Timothy J. Williams
Timothy J. Williams National Institutes of Health
Dorian O. Haskard
Dorian O. Haskard Imperial College London
Michel Aurrand-Lions
Michel Aurrand-Lions Aix-Marseille University
Mauro Perretti
Mauro Perretti Queen Mary University of London
Federica M. Marelli-Berg
Federica M. Marelli-Berg Queen Mary University of London
Charles D. Pusey
Charles D. Pusey Imperial College London
Roy R. Lobb
Roy R. Lobb Biogen (United States)
Paolo Meda
Paolo Meda University of Geneva
Peter J. Jose
Peter J. Jose University of Valencia
Elisabetta Dejana
Elisabetta Dejana Uppsala University

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