World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
60
Citations
12452
World Ranking
9722
National Ranking
2735

Biology and Biochemistry

D-Index
62
Citations
13568
World Ranking
10812
National Ranking
4694

Overview

Ziqiang Guan is affiliated with Duke University in the United States. Their research spans several domains primarily within biochemistry, genetics, molecular biology, and medicine. With 99 publications in biochemistry, genetics and molecular biology, and 70 in medicine, Guan's work covers a broad spectrum of life sciences.

The scientist's subfields of study include molecular biology, public health, environmental and occupational health, genetics, epidemiology, and infectious diseases.

  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Genetics
  • Epidemiology
  • Infectious Diseases

The main research topics addressed by Guan include carbohydrate chemistry and synthesis, bacterial genetics and biotechnology, streptococcal infections and treatments, glycosylation and glycoproteins research, antibiotic resistance in bacteria, pneumonia and respiratory infections, and studies on Vibrio bacteria.

  • Carbohydrate Chemistry and Synthesis
  • Bacterial Genetics and Biotechnology
  • Streptococcal Infections and Treatments
  • Glycosylation and Glycoproteins Research
  • Antibiotic Resistance in Bacteria
  • Pneumonia and Respiratory Infections
  • Vibrio bacteria research studies

Guan's recent publications demonstrate involvement in structural biology, microbiology, and cell biology. Selected recent papers include:

  • "Structural basis of NPR1 in activating plant immunity" (2022), published in Nature
  • "MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis" (2020), published in Nature Metabolism
  • "Phospholipid distribution in the cytoplasmic membrane of Gram-negative bacteria is highly asymmetric, dynamic, and cell shape-dependent" (2020), published in Science Advances
  • "Structural basis for inhibition and regulation of a chitin synthase from Candida albicans" (2022), published in Nature Structural & Molecular Biology
  • "Convergent evolution of bacterial ceramide synthesis" (2021), published in Nature Chemical Biology

Frequent co-authors collaborating with Guan include:

  • Kelli L. Palmer (15 joint publications)
  • Luke R. Joyce (12 joint publications)
  • Eric A. Klein (9 joint publications)
  • Christian Sohlenkamp (8 joint publications)
  • Miguel Ángel Vences-Guzmán (7 joint publications)

Guan's research has been published in several scientific venues with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory) - 18 publications
  • Journal of Biological Chemistry - 8 publications
  • Nature Structural & Molecular Biology - 3 publications
  • Proceedings of the National Academy of Sciences - 3 publications
  • Science Advances - 2 publications

Best Publications

  • Lipidomics reveals a remarkable diversity of lipids in human plasma

    Oswald Quehenberger;Aaron M. Armando;Alex H. Brown;Stephen B. Milne

  • Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

    D. Lee Gorden;David S. Myers;Pavlina T. Ivanova;Eoin Fahy

  • A Mouse Macrophage Lipidome

    Edward A. Dennis;Raymond A. Deems;Richard Harkewicz;Oswald Quehenberger

  • SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

    Vincent Cantagrel;Dirk J. Lefeber;Bobby G. Ng;Ziqiang Guan

  • GASEOUS CONFORMATIONAL STRUCTURES OF CYTOCHROME C

    Fred W. McLafferty;Ziqiang Guan;Ulrich Haupts;Troy D. Wood

  • Discovery of new biosynthetic pathways: the lipid A story

    Christian R.H. Raetz;Ziqiang Guan;Brian O. Ingram;David A. Six

  • Cardiolipin and the osmotic stress responses of bacteria

    Tatyana Romantsov;Ziqiang Guan;Janet M. Wood

  • Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates

    Brandon K. Tan;Mikhail V Bogdanov;Jinshi Zhao;William Dowhan

  • Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

    Ben C. Chung;Jinshi Zhao;Robert A. Gillespie;Do-Yeon Kwon

  • Structural basis of NPR1 in activating plant immunity

    Unknown

  • Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

    Eric A Ortlund;Yoonkwang Lee;Isaac H Solomon;Janet M Hager

  • Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis

    Ji Zhang;Ziqiang Guan;Anne N. Murphy;Sandra E. Wiley

  • Subcellular organelle lipidomics in TLR-4-activated macrophages,

    Alexander Y. Andreyev;Eoin Fahy;Ziqiang Guan;Samuel Kelly

  • A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin.

    Amanda L. McClerren;Stephanie Endsley;Jason L. Bowman;Niels H. Andersen

  • Daptomycin Resistance in Enterococci Is Associated with Distinct Alterations of Cell Membrane Phospholipid Content

    Nagendra N. Mishra;Arnold S. Bayer;Arnold S. Bayer;Truc T. Tran;Truc T. Tran;Yousif Shamoo

  • An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.

    Aixin Yan;Ziqiang Guan;Christian R. H. Raetz

  • MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis

    Chien-Kuang Cornelia Ding;Joshua Rose;Tianai Sun;Jianli Wu

  • Structure and Biosynthesis of Free Lipid A Molecules That Replace Lipopolysaccharide in Francisella tularensis subsp. novicida

    Xiaoyuan Wang;Anthony A. Ribeiro;Ziqiang Guan;Sara C. McGrath

  • Attenuated virulence of a Francisella mutant lacking the lipid A 4′-phosphatase

    Xiaoyuan Wang;Anthony A. Ribeiro;Ziqiang Guan;Soman N. Abraham

  • Solution structure of the Set2–Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1

    Ming Li;Hemali P. Phatnani;Ziqiang Guan;Harvey Sage

  • 193 nm photodissociation of larger multiply-charged biomolecules

    Ziqiang Guan;Neil L. Kelleher;Peter B. O'Connor;David J. Aaserud

  • The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2.

    Kelly N. Nobles;Ziqiang Guan;Kunhong Xiao;Terrence G. Oas

  • Detection and characterization of methionine oxidation in peptides by collision-induced dissociation and electron capture dissociation.

    Ziqiang Guan;Nathan A. Yates;Ray Bakhtiar

Frequent Co-Authors

Christian R. H. Raetz
Christian R. H. Raetz Duke University
Sheo B. Singh
Sheo B. Singh MSD (United States)
Fernando Pelaez
Fernando Pelaez Spanish National Cancer Research Centre
Fred W. McLafferty
Fred W. McLafferty Cornell University
William Dowhan
William Dowhan The University of Texas Health Science Center at Houston
Daria J. Hazuda
Daria J. Hazuda MSD (United States)
Deborah L. Zink
Deborah L. Zink Weizenbaum-Institut
Edward A. Dennis
Edward A. Dennis University of California, San Diego
Gerald F. Bills
Gerald F. Bills The University of Texas Health Science Center at Houston
William C. Sessa
William C. Sessa Pfizer (United States)

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