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Microbiology

D-Index
85
Citations
23859
World Ranking
884
National Ranking
410

Overview

Robert K. Ernst is affiliated with the University of Maryland, Baltimore in the United States. Their research spans multiple fields, primarily within Biochemistry, Genetics and Molecular Biology, and Medicine. These broad fields include significant work in subfields such as Molecular Biology, Immunology, Epidemiology, Molecular Medicine, and Infectious Diseases.

The scientist's publication record includes research on key topics related to microbiology and immunology. The main areas of focus in their work are:

  • Antibiotic Resistance in Bacteria
  • Immune Response and Inflammation
  • Metabolomics and Mass Spectrometry Studies
  • SARS-CoV-2 and COVID-19 Research
  • Lipid Membrane Structure and Behavior
  • Influenza Virus Research Studies
  • Bacterial Identification and Susceptibility Testing

Research outputs are published frequently in several venues, with a notable number of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Vaccine
  • The Journal of Immunology
  • Journal of Cystic Fibrosis
  • npj Vaccines

Frequent co-authors contributing to joint work include:

  • David R. Goodlett
  • Richard D. Smith
  • Alison Scott
  • Courtney E. Chandler
  • Hyojik Yang

Representative recent papers authored or co-authored by Robert K. Ernst include:

  • "An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice," 2022, Science Translational Medicine
  • "Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection," 2022, Cell Metabolism
  • "An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice," 2022, PubMed
  • "Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids," 2020, Scientific Reports
  • "Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant Enterobacterales in the United States," 2021, mBio

Best Publications

  • Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

    Jon A. Hagar;Daniel A. Powell;Youssef Aachoui;Robert K. Ernst

  • LPS, TLR4 and infectious disease diversity

    Samuel I. Miller;Robert K. Ernst;Martin W. Bader

  • Human Toll-like receptor 4 recognizes host-specific LPS modifications

    Adeline M. Hajjar;Robert K. Ernst;Jeff H. Tsai;Christopher B. Wilson

  • Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa.

    Robert K. Ernst;Eugene C. Yi;Lin Guo;Kheng B. Lim

  • Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium.

    John S. Gunn;Sara S. Ryan;Jennifer C. Van Velkinburgh;Robert K. Ernst

  • Homeoviscous Adaptation and the Regulation of Membrane Lipids.

    Robert Ernst;Christer S Ejsing;Bruno Antonny

  • The TLR4 antagonist Eritoran protects mice from lethal influenza infection

    Kari Ann Shirey;Wendy Lai;Alison J. Scott;Michael Lipsky

  • PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A.

    Samuel M. Moskowitz;Robert K. Ernst;Samuel I. Miller

  • Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens.

    Leigh A. Knodler;Leigh A. Knodler;Shauna M. Crowley;Ho Pan Sham;Hyungjun Yang

  • Colistin-Resistant Acinetobacter baumannii: Beyond Carbapenem Resistance

    Zubair A. Qureshi;Lauren E. Hittle;Jessica A. O'Hara;Jesabel I. Rivera

  • Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.

    David A. D'Argenio;Manhong Wu;Lucas R. Hoffman;Hemantha D. Kulasekara

  • Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

    Danielle M. Pilla;Jon A. Hagar;Arun K. Haldar;Ashley K. Mason

  • Pseudomonas aeruginosa activates caspase 1 through Ipaf

    Edward A. Miao;Robert K. Ernst;Monica Dors;Dat P. Mao

  • Activation of the Unfolded Protein Response by Lipid Bilayer Stress

    Kristina Halbleib;Kristina Pesek;Roberto Covino;Harald F. Hofbauer

  • Variation in lipid A structure in the pathogenic yersiniae.

    Roberto Rebeil;Robert K. Ernst;Brian B. Gowen;Samuel I. Miller

  • Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity.

    Robert K. Ernst;Tina Guina;Samuel I. Miller

  • The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.

    Amy E. Pasquinelli;Robert K. Ernst;Elsebet Lund;Christian Grimm

  • The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER

    Robert Ernst;Britta Mueller;Hidde L. Ploegh;Christian Schlieker

  • Anaerobiosis, type 1 fimbriae, and growth phase are factors that affect invasion of HEp-2 cells by Salmonella typhimurium.

    R K Ernst;D M Dombroski;J M Merrick

  • Structural basis of MsbA-mediated lipopolysaccharide transport

    Wei Mi;Yanyan Li;Sung Hwan Yoon;Robert K. Ernst

  • Lack of In Vitro and In Vivo Recognition of Francisella tularensis Subspecies Lipopolysaccharide by Toll-Like Receptors

    Adeline M. Hajjar;Megan D. Harvey;Scott A. Shaffer;David R. Goodlett

  • Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains

    Laurence Rohmer;Christine Fong;Simone Abmayr;Michael Wasnick

Frequent Co-Authors

Samuel I. Miller
Samuel I. Miller University of Washington
David R. Goodlett
David R. Goodlett University of Victoria
Gerhard Hummer
Gerhard Hummer Max Planck Society
Yohei Doi
Yohei Doi University of Pittsburgh
Christian Melander
Christian Melander University of Notre Dame
Robert S. Chapkin
Robert S. Chapkin Texas A&M University
Ilya Levental
Ilya Levental The University of Texas Health Science Center at Houston
David A. Rasko
David A. Rasko University of Maryland, Baltimore
John S. Gunn
John S. Gunn Nationwide Children's Hospital
Christopher B. Wilson
Christopher B. Wilson Bill & Melinda Gates Foundation

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