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Biology and Biochemistry

D-Index
59
Citations
14065
World Ranking
12429
National Ranking
5320

Overview

M. Stephen Trent is affiliated with the University of Georgia in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a substantial portfolio of 70 publications in these areas. The scientist's work spans several subfields including genetics, molecular medicine, molecular biology, endocrinology, and ecology.

The topics of M. Stephen Trent's research include antibiotic resistance in bacteria, bacterial genetics and biotechnology, lipid membrane structure and behavior, bacteriophages and microbial interactions, Escherichia coli and Vibrio bacteria research studies, and metabolomics and mass spectrometry studies.

They have contributed extensively to academic literature with notable recent papers such as:

  • Absence of YhdP, TamB, and YdbH leads to defects in glycerophospholipid transport and cell morphology in Gram-negative bacteria (2022), published in PLoS Genetics
  • The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport (2020), published in eLife
  • Structural basis of lipopolysaccharide maturation by the O-antigen ligase (2022), published in Nature
  • CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae (2020), published in Cell Reports
  • A novel type of colistin resistance genes selected from random sequence space (2021), published in PLoS Genetics

The scientist frequently publishes in journals such as bioRxiv (Cold Spring Harbor Laboratory), mBio, Proceedings of the National Academy of Sciences, Analytical Chemistry, and the Journal of Bacteriology.

M. Stephen Trent has collaborated regularly with co-authors including Carmen M. Herrera, Brent W. Simpson, Martin V. Douglass, Matthew J. Powers, and Bradley J. Voss. These collaborative relationships have contributed to a body of work that intersects molecular biology and bacterial genetics.

Best Publications

  • LIPID A MODIFICATION SYSTEMS IN GRAM-NEGATIVE BACTERIA

    Christian R. H. Raetz;C. Michael Reynolds;M. Stephen Trent;Russell E. Bishop

  • Biosynthesis and Export of Bacterial Lipopolysaccharides

    Chris Whitfield;M. Stephen Trent

  • Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis

    Brittany D. Needham;M. Stephen Trent

  • Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.

    Russell E. Bishop;Russell E. Bishop;Henry S. Gibbons;Tina Guina;M. Stephen Trent

  • An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor.

    M. Stephen Trent;Anthony A. Ribeiro;Shanhua Lin;Robert J. Cotter

  • Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation

    T. W. Cullen;W. B. Schofield;N. A. Barry;E. E. Putnam

  • Diversity of endotoxin and its impact on pathogenesis.

    M Stephen Trent;Christopher M Stead;An X Tran;Jessica V Hankins

  • Pushing the envelope: LPS modifications and their consequences

    Brent W. Simpson;M. Stephen Trent;M. Stephen Trent

  • Invited review: Diversity of endotoxin and its impact on pathogenesis:

    M. Stephen Trent;Christopher M. Stead;An X. Tran;Jessica V. Hankins

  • The pmrCAB Operon Mediates Polymyxin Resistance in Acinetobacter baumannii ATCC 17978 and Clinical Isolates through Phosphoethanolamine Modification of Lipid A

    Luis A. Arroyo;Carmen M. Herrera;Lucia Fernandez;Jessica V. Hankins

  • A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium.

    M. Stephen Trent;Wendy Pabich;Christian R.H. Raetz;Samuel I. Miller

  • Modulating the innate immune response by combinatorial engineering of endotoxin

    Brittany D. Needham;Sean M. Carroll;David K. Giles;George Georgiou

  • Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae

    Victor I. Band;Emily K. Crispell;Brooke A. Napier;Carmen M. Herrera

  • The Power of Asymmetry: Architecture and Assembly of the Gram-Negative Outer Membrane Lipid Bilayer

    Jeremy C. Henderson;Shawn M. Zimmerman;Alexander A. Crofts;Joseph M. Boll

  • Helicobacter pylori versus the Host: Remodeling of the Bacterial Outer Membrane Is Required for Survival in the Gastric Mucosa

    Thomas W. Cullen;David K. Giles;Lindsey N. Wolf;Chantal Ecobichon;Chantal Ecobichon

  • Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in Gram-positive and Gram-negative bacteria

    Jessica V. Hankins;James A. Madsen;David K. Giles;Jennifer S. Brodbelt

  • Defining Gene-Phenotype Relationships in Acinetobacter baumannii through One-Step Chromosomal Gene Inactivation

    Ashley T. Tucker;Emily M. Nowicki;Joseph M. Boll;Gregory A. Knauf

  • Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm.

    M. Stephen Trent;Anthony A. Ribeiro;William T. Doerrler;Shanhua Lin

  • Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides

    Carmen M. Herrera;Jessica V. Hankins;M. Stephen Trent

  • Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition

    Jessica V. Hankins;James A. Madsen;David K. Giles;Brandon M. Childers

Frequent Co-Authors

Jennifer S. Brodbelt
Jennifer S. Brodbelt The University of Texas at Austin
Christian R. H. Raetz
Christian R. H. Raetz Duke University
Robert J. Cotter
Robert J. Cotter Johns Hopkins University School of Medicine
Samuel I. Miller
Samuel I. Miller University of Washington
Chris Whitfield
Chris Whitfield University of Guelph
George Georgiou
George Georgiou The University of Texas at Austin
Ziqiang Guan
Ziqiang Guan Duke University
Robert E. W. Hancock
Robert E. W. Hancock University of British Columbia
Ivo G. Boneca
Ivo G. Boneca Institut Pasteur
Edward M. Marcotte
Edward M. Marcotte The University of Texas at Austin

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