World's Best Scientists 2026 revealed!
Christian R. H. Raetz

Christian R. H. Raetz

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
40323
World Ranking
1252
National Ranking
739

Overview

Christian R. H. Raetz is primarily affiliated with Duke University in the United States. Their research contributions span several areas within biochemistry, genetics, and molecular biology, with a focus on enzyme structure and function, antibiotic resistance in bacteria, and biochemical and molecular research.

The scientist's recent publications reflect a strong emphasis on biochemical mechanisms related to lipid A modification and bacterial resistance. These include:

  • Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance (2023, Biochemistry)
  • NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis (2020, UNC Libraries)
  • Crystallization and preliminary X-ray diffraction analysis of phospholipid-bound Sfh1p, a member of the Saccharomyces cerevisiae Sec14p-like phosphatidylinositol transfer protein family (2020, UNC Libraries)

Their frequent co-authors include Daniel Muñoz-Escudero, Steven D. Breazeale, Myeongseon Lee, Ziqiang Guan, and Marcelo C. Sousa, indicating collaborative efforts in biochemical and molecular biology fields.

Christian R. H. Raetz has published predominantly in the venues UNC Libraries and Biochemistry. These platforms highlight both foundational research and specialized biochemical studies.

The scientist's work integrates subfields such as materials chemistry, molecular medicine, and molecular biology, which align with the broader themes of their research topics.

Main topics in their research are:

  • Enzyme Structure and Function
  • Antibiotic Resistance in Bacteria
  • Biochemical and Molecular Research

The integration of these topics and fields underscores a multidisciplinary approach to understanding molecular mechanisms that influence bacterial pathogenesis and resistance, with implications for molecular medicine and biochemical innovation.

Best Publications

  • Update of the LIPID MAPS comprehensive classification system for lipids

    Eoin Fahy;Shankar Subramaniam;Robert C. Murphy;Masahiro Nishijima

  • LMSD: LIPID MAPS structure database.

    Manish Sud;Eoin Fahy;Dawn Cotter;Alex Brown

  • LIPID A MODIFICATION SYSTEMS IN GRAM-NEGATIVE BACTERIA

    Christian R. H. Raetz;C. Michael Reynolds;M. Stephen Trent;Russell E. Bishop

  • Lipidomics reveals a remarkable diversity of lipids in human plasma

    Oswald Quehenberger;Aaron M. Armando;Alex H. Brown;Stephen B. Milne

  • Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.

    Christian R. H. Raetz;Richard I. Ulevitch;Samuel D. Wright;Carol H. Sibley

  • Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

    Nathanael J. Spann;Lana X. Garmire;Jeffrey G. McDonald;David S. Myers

  • Bacterial polysaccharide synthesis and gene nomenclature

    Peter R. Reeves;Matthew Hobbs;Miguel A. Valvano;Mikael Skurnik

  • Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.

    Russell E. Bishop;Russell E. Bishop;Henry S. Gibbons;Tina Guina;M. Stephen Trent

  • An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor.

    M. Stephen Trent;Anthony A. Ribeiro;Shanhua Lin;Robert J. Cotter

  • Biosynthesis and function of phospholipids in Escherichia coli.

    Christian R H Raetz;William Dowhan

  • Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR

    Peter M. Hwang;Wing-Yiu Choy;Eileen I. Lo;Lu Chen

  • A Left-Handed Parallel β Helix in the Structure of UDP-N-Acetylglucosamine Acyltransferase

    Christian R. H. Raetz;Steven L. Roderick

  • A Mouse Macrophage Lipidome

    Edward A. Dennis;Raymond A. Deems;Richard Harkewicz;Oswald Quehenberger

  • SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

    Vincent Cantagrel;Dirk J. Lefeber;Bobby G. Ng;Ziqiang Guan

  • Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitate.

    Zhimin Zhou;Shanhua Lin;Robert J. Cotter;Christian R.H. Raetz

  • Lipid A Modifications in Polymyxin-resistant Salmonella typhimurium PMRA-DEPENDENT 4-AMINO-4-DEOXY-l-ARABINOSE, AND PHOSPHOETHANOLAMINE INCORPORATION

    Zhimin Zhou;Anthony A. Ribeiro;Shanhua Lin;Robert J. Cotter

  • Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli.

    Teru Ogura;Koichi Inoue;Takashi Tatsuta;Toshinobu Suzaki

  • Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB.

    Tony Clementz;Zhimin Zhou;Christian R. H. Raetz

  • MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli.

    William T. Doerrler;Henry S. Gibbons;Christian R.H. Raetz

  • A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium.

    M. Stephen Trent;Wendy Pabich;Christian R.H. Raetz;Samuel I. Miller

Frequent Co-Authors

Ziqiang Guan
Ziqiang Guan Duke University
Robert J. Cotter
Robert J. Cotter Johns Hopkins University School of Medicine
Shankar Subramaniam
Shankar Subramaniam University of California, San Diego
Edward A. Dennis
Edward A. Dennis University of California, San Diego
Robert C. Murphy
Robert C. Murphy University of Colorado Denver
M. Stephen Trent
M. Stephen Trent University of Georgia
David W. Russell
David W. Russell University of Washington
Alfred H. Merrill
Alfred H. Merrill Georgia Institute of Technology
Christopher K. Glass
Christopher K. Glass University of California, San Diego
Roy Curtiss
Roy Curtiss University of Florida

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens up a variety of rewarding career options in healthcare, research, and public health. For students and professionals seeking flexibility, many accredited universities now offer robust online degree and certification pathways.

Those interested in advanced nursing roles may consider the 1 year post master's fnp online programs, which provide a fast track to becoming a Family Nurse Practitioner. Alternatively, registered nurses can expand their expertise and job opportunities through convenient rn to bsn online programs.

For those passionate about nutrition science, the best online registered dietitian programs deliver quality education at affordable rates. Additionally, students aspiring to move into healthcare administration can quickly enhance their credentials through 1 year mha programs online.

These online programs offer flexible learning opportunities to help students advance their careers while balancing personal and professional commitments.

Best Scientists Citing Christian R. H. Raetz

Trending Scientists