What is he best known for?
The fields of study he is best known for:
Guido Franzoso mostly deals with Transcription factor, Cell biology, NF-κB, Tumor necrosis factor alpha and NFKB1.
In his work, Downregulation and upregulation is strongly intertwined with Kinase, which is a subfield of Transcription factor.
His Cell biology research includes elements of Biochemistry, Warburg effect and Energy homeostasis.
His research integrates issues of Carcinogenesis and Programmed cell death in his study of NF-κB.
He has included themes like Apoptosis and Cancer research in his Tumor necrosis factor alpha study.
As part of one scientific family, Guido Franzoso deals mainly with the area of NFKB1, narrowing it down to issues related to the Molecular biology, and often Transactivation, Rel homology domain, Function and Proto-Oncogene Proteins c-rel.
His most cited work include:
- Structure, regulation and function of NF-kappa B. (1960 citations)
- Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation (1310 citations)
- Requirement for NF-κB in osteoclast and B-cell development (890 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cell biology, Transcription factor, NF-κB, Programmed cell death and Cancer research.
His work carried out in the field of Cell biology brings together such families of science as Tumor necrosis factor alpha, Immunology and Apoptosis.
His studies deal with areas such as Molecular biology, Downregulation and upregulation, Transcription and Cytokine as well as Transcription factor.
His Molecular biology research integrates issues from NFKB1, Ankyrin, DNA-binding protein, Transactivation and Ankyrin repeat.
Guido Franzoso works mostly in the field of Programmed cell death, limiting it down to topics relating to Receptor and, in certain cases, Cytoprotection, as a part of the same area of interest.
His Cancer research research is multidisciplinary, relying on both Carcinogenesis, Cancer, Inflammation, Regulator and Multiple myeloma.
He most often published in these fields:
- Cell biology (50.41%)
- Transcription factor (29.27%)
- NF-κB (26.02%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (21.95%)
- Cancer (9.76%)
- NF-κB (26.02%)
In recent papers he was focusing on the following fields of study:
Guido Franzoso mainly focuses on Cancer research, Cancer, NF-κB, Cancer cell and Carcinogenesis.
His work investigates the relationship between Cancer research and topics such as Inflammation that intersect with problems in Downregulation and upregulation, Transcriptional regulation, Clinical significance and Intracellular.
He has researched Cancer in several fields, including NFKB1, Reprogramming, Antigen, Disease and Cytotoxic T cell.
Guido Franzoso combines subjects such as Transcription factor, Pathogenesis and Multiple myeloma with his study of NF-κB.
Guido Franzoso interconnects Cell, Oxidative phosphorylation, Mitochondrion, Cell biology and Energy homeostasis in the investigation of issues within Transcription factor.
Guido Franzoso combines subjects such as Chromatin, Telomerase RNA component, Telomerase, Telomerase reverse transcriptase and Telomere with his study of Carcinogenesis.
Between 2013 and 2021, his most popular works were:
- Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages (103 citations)
- Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity (91 citations)
- Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors (73 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Cancer research, Cancer, NF-κB, NFKB1 and Pathogenesis.
His research integrates issues of Cancer cell, Protein subunit and Carcinogenesis in his study of Cancer research.
His NF-κB research is included under the broader classification of Immunology.
His NFKB1 research incorporates elements of Inflammation, Multiple myeloma, Bortezomib and Toxicity.
The study incorporates disciplines such as Autophagy, Transcription factor, Programmed cell death, Necroptosis and Regulator in addition to Pathogenesis.
His research in the fields of IκB kinase overlaps with other disciplines such as Human health.
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