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Biology and Biochemistry

D-Index
59
Citations
21408
World Ranking
12277
National Ranking
943

Overview

Guido Franzoso is affiliated with Imperial College London in the United Kingdom. Their research primarily intersects the areas of biochemistry, genetics, molecular biology, medicine, and immunology. Key subfields of study include molecular biology, immunology, cancer research, oncology, and epidemiology.

The main research topics they focus on are:

  • NF-κB Signaling Pathways
  • Immune cells in cancer
  • Histone Deacetylase Inhibitors Research
  • Cancer, Stress, Anesthesia, and Immune Response
  • Cancer, Lipids, and Metabolism
  • Immunotherapy and Immune Responses
  • Ubiquitin and proteasome pathways

Among their recent published papers are:

  • "NF-κB: Governing Macrophages in Cancer" (2024), published in Genes
  • "Apoptosis in mesenchymal stromal cells activates an immunosuppressive secretome predicting clinical response in Crohn's disease" (2023), published in Molecular Therapy
  • "NF-κB: blending metabolism, immunity, and inflammation" (2022), published in Trends in Immunology
  • "Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma" (2021), published in Journal of Clinical Investigation
  • "Life, death, and autophagy in cancer: NF-κB turns up everywhere" (2020), published in Cell Death and Disease

Guido Franzoso has also contributed to book publications, including "NF-κB Transcription Factors" published by Springer Science+Business Media in 2021.

Frequently publishing in specific outlets, their work appears notably in:

  • Methods in molecular biology
  • Biomedicines
  • Trends in Immunology
  • Cell Death and Disease
  • Genes

Collaborations include frequent coauthors such as Daria Capece, Daniela Verzella, Francesca Zazzeroni, Davide Vecchiotti, and Jessica Cornice.

Best Publications

  • Structure, regulation and function of NF-kappa B.

    Ulrich Siebenlist;Guido Franzoso;Keith Brown

  • Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

    Keith Brown;Susan Gerstberger;Louise Carlson;Guido Franzoso

  • Requirement for NF-κB in osteoclast and B-cell development

    Guido Franzoso;Louise Carlson;Lianping Xing;Ljiljana Poljak

  • Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling

    Enrico De Smaele;Francesca Zazzeroni;Salvatore Papa;Dung U. Nguyen

  • Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

    Can G. Pham;Concetta Bubici;Francesca Zazzeroni;Salvatore Papa

  • The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers

    Vincent Bours;Guido Franzoso;Viola Azarenko;Sun Park

  • Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture

    Guido Franzoso;Louise Carlson;Ljiljana Poljak;Elizabeth W. Shores

  • The nuclear factor kappa B signaling pathway: Integrating metabolism with inflammation

    Laura Tornatore;Anil K. Thotakura;Jason Bennett;Marta Moretti

  • Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

    C Bubici;S Papa;K Dean;G Franzoso

  • Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2.

    Salvatore Papa;Francesca Zazzeroni;Concetta Bubici;Shanthi Jayawardena

  • The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition.

    G. Franzoso;Vincent Bours;S. Park;M. Tomita-Yamaguchi

  • NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration.

    Claudio Mauro;Shi Chi Leow;Elena Anso;Sonia Rocha

  • Linking JNK signaling to NF-κB: a key to survival

    Salvatore Papa;Francesca Zazzeroni;Can G. Pham;Concetta Bubici

  • CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells.

    Bryan C Barnhart;Patrick Legembre;Eric Pietras;Concetta Bubici

  • TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis

    Haining Yang;Maurizio Bocchetta;Barbara Kroczynska;Amira G. Elmishad

  • Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation

    Haining Yang;Zeyana Rivera;Sandro Jube;Masaki Nasu

  • The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.

    S Papa;C Bubici;F Zazzeroni;F Zazzeroni;C G Pham

  • Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha.

    Lucia Baldi;Keith Brown;Guido Franzoso;Ulrich Siebenlist

  • Life, death, and autophagy in cancer: NF-κB turns up everywhere.

    Daniela Verzella;Alessandra Pescatore;Daria Capece;Daria Capece;Davide Vecchiotti

  • STRUCTURE, REGULATION AND FUNCTION OF NF-1d3

    Ulrich Sieben;Guido Franzoso;Keith Brown

Frequent Co-Authors

Ulrich Siebenlist
Ulrich Siebenlist National Institutes of Health
Yang-Xin Fu
Yang-Xin Fu Tsinghua University
Vincent Bours
Vincent Bours University of Liège
Simona Maria Monti
Simona Maria Monti University of Naples Federico II
Philippe K. Zysset
Philippe K. Zysset University of Bern
Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Marcus E. Peter
Marcus E. Peter Northwestern University
Vinay Tergaonkar
Vinay Tergaonkar Agency for Science, Technology and Research
Maria-Luisa Alegre
Maria-Luisa Alegre University of Chicago
Jane F. Apperley
Jane F. Apperley Imperial College London

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