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Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
111
Citations
51256
World Ranking
231
National Ranking
107

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 1997 - Oswald Avery Award, Infectious Diseases Society of America

Overview

Samuel I. Miller is affiliated with the University of Washington in the United States. Their research primarily focuses on biochemistry, genetics, molecular biology, and medicine, with specialized attention to molecular biology, pulmonary and respiratory medicine, genetics, oncology, and molecular medicine.

The major topics covered in Miller's work include cystic fibrosis research advances, lipid membrane structure and behavior, bacterial genetics and biotechnology, CAR-T cell therapy research, gut microbiota and health, antibiotic resistance in bacteria, and protein structure and dynamics.

Notable recent publications by Samuel I. Miller include:

  • Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure (2020, Nature Medicine)
  • Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues (2022, Nature Cancer)
  • CFTR dysregulation drives active selection of the gut microbiome (2020, PLoS Pathogens)
  • Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome (2020, Thorax)
  • Structure and lipid dynamics in the maintenance of lipid asymmetry inner membrane complex of A. baumannii (2021, Communications Biology)

Frequent co-authors collaborating with Miller include Lucas R. Hoffman, Christopher E. Pope, Hillary S. Hayden, Alexander Eng, and M. Brittnacher.

Their work has been published repeatedly in venues such as Nature Cancer, mBio, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, and the International Journal of Integrated Care.

Samuel I. Miller received the Oswald Avery Award from the Infectious Diseases Society of America in 1997.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients.

    Eric E. Smith;Danielle G. Buckley;Zaining Wu;Channakhone Saenphimmachak

  • Aminoglycoside antibiotics induce bacterial biofilm formation

    Lucas R. Hoffman;David A. D'Argenio;Michael J. MacCoss;Zhaoying Zhang

  • Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

    Edward A Miao;Celia M Alpuche-Aranda;Monica Dors;April E Clark

  • LPS, TLR4 and infectious disease diversity

    Samuel I. Miller;Robert K. Ernst;Martin W. Bader

  • Salmonellae interplay with host cells

    Andrea Haraga;Maikke B. Ohlson;Samuel I. Miller

  • Lipid A Acylation and Bacterial Resistance against Vertebrate Antimicrobial Peptides

    Lin Guo;Kheng B Lim;Cristina M Poduje;Morad Daniel

  • PmrA–PmrB‐regulated genes necessary for 4‐aminoarabinose lipid A modification and polymyxin resistance

    John S. Gunn;Kheng B. Lim;Jackie Krueger;Kevin Kim

  • Human Toll-like receptor 4 recognizes host-specific LPS modifications

    Adeline M. Hajjar;Robert K. Ernst;Jeff H. Tsai;Christopher B. Wilson

  • Regulation of Lipid A Modifications by Salmonella typhimurium Virulence Genes phoP-phoQ

    Lin Guo;Kheng B. Lim;Kheng B. Lim;John S. Gunn;John S. Gunn;Brian Bainbridge;Brian Bainbridge

  • Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase

    Martin W. Bader;Sarah Sanowar;Margaret E. Daley;Anna R. Schneider

  • Salmonella: a model for bacterial pathogenesis

    Michael E. Ohl;Samuel I. Miller

  • Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa.

    Robert K. Ernst;Eugene C. Yi;Lin Guo;Kheng B. Lim

  • Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo

    K. B. Low;M. Ittensohn;T. Le;J. Platt

  • Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium.

    John S. Gunn;Sara S. Ryan;Jennifer C. Van Velkinburgh;Robert K. Ernst

  • Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa

    Lucas R. Hoffman;Éric Déziel;David A D'Argenio;François Lépine

  • Salmonellae interactions with host processes

    Doris L. LaRock;Anu Chaudhary;Samuel I. Miller

  • Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175

    Liliana B. Menalled;Andrea E. Kudwa;Sam Miller;Jon Fitzpatrick

  • PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance.

    J S Gunn;S I Miller

  • Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.

    Russell E. Bishop;Russell E. Bishop;Henry S. Gibbons;Tina Guina;M. Stephen Trent

  • PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A.

    Samuel M. Moskowitz;Robert K. Ernst;Samuel I. Miller

Frequent Co-Authors

Robert K. Ernst
Robert K. Ernst University of Maryland, Baltimore
Lucas R. Hoffman
Lucas R. Hoffman University of Washington
David R. Goodlett
David R. Goodlett University of Victoria
Bonnie W. Ramsey
Bonnie W. Ramsey University of Washington
Jane L. Burns
Jane L. Burns University of Washington
John S. Gunn
John S. Gunn Nationwide Children's Hospital
Elhanan Borenstein
Elhanan Borenstein Tel Aviv University
Christopher B. Wilson
Christopher B. Wilson Bill & Melinda Gates Foundation
Rachel E. Klevit
Rachel E. Klevit University of Washington
Rajinder Kaul
Rajinder Kaul University of Washington

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