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Microbiology

D-Index
69
Citations
21213
World Ranking
2010
National Ranking
851

Overview

Richard P. Darveau is affiliated with the University of Washington in the United States. Their research primarily spans the fields of Dentistry and Medicine, with a focus on the subfields of Periodontics, Molecular Biology, Immunology, Public Health, Environmental and Occupational Health, and Physiology.

The scientist's main topics of investigation include:

  • Oral microbiology and periodontitis research
  • Gut microbiota and health
  • Oral Health Pathology and Treatment
  • Immune Response and Inflammation
  • Salivary Gland Disorders and Functions
  • Mycobacterium research and diagnosis
  • HIV/AIDS oral health manifestations

Notable recent publications include:

  • "Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer" (2021), published in Cell Host & Microbe
  • "Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin" (2020), published in PLoS Pathogens
  • "Oral biofilms revisited: A novel host tissue of bacteriological origin" (2021), published in Periodontology 2000
  • "Human variation in gingival inflammation" (2021), published in Proceedings of the National Academy of Sciences
  • "Maintaining homeostatic control of periodontal epithelial tissue" (2021), published in Periodontology 2000

The scientist has frequently published in journals such as:

  • Periodontology 2000
  • Proceedings of the National Academy of Sciences
  • Journal of Endodontics
  • Frontiers in Oral Health
  • Journal of Periodontology

Frequent collaborators include:

  • Jeffrey S. McLean
  • Sumita Jain
  • Ana M. Chang
  • Shatha Bamashmous
  • Georgios A. Kotsakis

Best Publications

  • Periodontitis: a polymicrobial disruption of host homeostasis

    Richard P. Darveau

  • The keystone-pathogen hypothesis

    George Hajishengallis;Richard P. Darveau;Michael A. Curtis

  • Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

    George Hajishengallis;Shuang Liang;Mark A. Payne;Ahmed Hashim

  • Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains.

    Richardp . Darveau;Robert E. W. Hancock

  • The microbial challenge in periodontitis

    Richard P. Darveau;Anne Tanner;Roy C. Page

  • Regulation of Lipid A Modifications by Salmonella typhimurium Virulence Genes phoP-phoQ

    Lin Guo;Kheng B. Lim;Kheng B. Lim;John S. Gunn;John S. Gunn;Brian Bainbridge;Brian Bainbridge

  • Porphyromonas gingivalis Lipopolysaccharide Contains Multiple Lipid A Species That Functionally Interact with Both Toll-Like Receptors 2 and 4

    Richard P. Darveau;Thu Thao T Pham;Kayde Lemley;Robert A. Reife

  • Inducible Expression of Human β-Defensin 2 by Fusobacterium nucleatum in Oral Epithelial Cells: Multiple Signaling Pathways and Role of Commensal Bacteria in Innate Immunity and the Epithelial Barrier

    Suttichai Krisanaprakornkit;Janet R. Kimball;Aaron Weinberg;Richard P. Darveau

  • Porphyromonas gingivalis as a Potential Community Activist for Disease

    R.P. Darveau;G. Hajishengallis;M.A. Curtis

  • Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis

    Richard P. Darveau;Carol M. Belton;Robert A. Reife;Richard J. Lamont

  • Microbial Shift and Periodontitis

    Alex B. Berezow;Richard P. Darveau

  • Energy transduction between membranes. TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to the outer membrane receptor FepA.

    Jonathan T. Skare;Brian M M Ahmer;Carrie L. Seachord;Richard P. Darveau

  • Lipopolysaccharide Heterogeneity: Innate Host Responses to Bacterial Modification of Lipid A Structure

    D.R. Dixon;R.P. Darveau

  • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide

    Timothy J. Sellati;Deborah A. Bouis;Richard L. Kitchens;Richard P. Darveau;Richard P. Darveau

  • Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system.

    Brian W. Bainbridge;Richard P. Darveau

  • The Relationship of the Oral Microbiotia to Periodontal Health and Disease

    Michael A. Curtis;Camille Zenobia;Richard P. Darveau

  • Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion.

    R P Darveau;M D Cunningham;T Bailey;C Seachord

  • Contribution of Porphyromonas gingivalis lipopolysaccharide to periodontitis

    Sumita Jain;Richard P. Darveau

  • Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-κB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.

    Thanuja D K Herath;Richard P. Darveau;Chaminda J. Seneviratne;Cun Yu Wang

  • MD-2 Mediates the Ability of Tetra-Acylated and Penta-Acylated Lipopolysaccharides to Antagonize Escherichia coli Lipopolysaccharide at the TLR4 Signaling Complex

    Stephen R. Coats;Thu Thao T Pham;Brian W. Bainbridge;Robert A. Reife

  • Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities.

    Stephen R. Coats;Jace W. Jones;Christopher T. Do;Pamela H. Braham

Frequent Co-Authors

Lijian Jin
Lijian Jin University of Hong Kong
Cun-Yu Wang
Cun-Yu Wang University of California, Los Angeles
Lakshman P. Samaranayake
Lakshman P. Samaranayake University of Hong Kong
Yu Wang
Yu Wang University of Hong Kong
Michael A. Curtis
Michael A. Curtis King's College London
Caroline Attardo Genco
Caroline Attardo Genco Tufts University
Robert K. Ernst
Robert K. Ernst University of Maryland, Baltimore
George Hajishengallis
George Hajishengallis University of Pennsylvania
Wai K. Leung
Wai K. Leung University of Hong Kong
Richard J. Lamont
Richard J. Lamont University of Louisville

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