Fernando Pelaez

Overview

Best Publications

• Platensimycin is a selective FabF inhibitor with potent antibiotic properties

  Jun Wang;Stephen M. Soisson;Katherine Young;Wesley Shoop;Wesley Shoop

  1001
  Citations

• Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.

  Bei Zhang;Gino Salituro;Deborah Szalkowski;Zhihua Li

  627
  Citations

• Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties.

  Jun Wang;Srinivas Kodali;Sang Ho Lee;Andrew Galgoci

  465
  Citations

• Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors

  J. Onishi;M. Meinz;J. Thompson;J. Curotto

  424
  Citations

• Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain).

  Antonio González del Val;Gonzalo Platas;Angela Basilio;Angeles Cabello

  423
  Citations

• Screening of basidiomycetes for antimicrobial activities.

  Inmaculada Suay;Francisco Arenal;Francisco J. Asensio;Angela Basilio

  365
  Citations

• The historical delivery of antibiotics from microbial natural products—Can history repeat?

  Fernando Peláez

  336
  Citations

• Primary structure and inhibition of protein synthesis in eukaryotic cell-free system of a novel thionin, γ-hordothionin, from barley endosperm.

  Enrique Mendez;Aurora Moreno;Francisco Colilla;Fernando Pelaez

  325
  Citations

• Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy.

  Sheo B Singh;Hiranthi Jayasuriya;John G Ondeyka;Kithsiri B Herath

  296
  Citations

• Farnesoid X receptor activates transcription of the phospholipid pump MDR3.

  Li Huang;Annie Zhao;Jane-L. Lew;Theresa Zhang

  294
  Citations

• Screening of 68 species of basidiomycetes for enzymes involved in lignin degradation

  F. Peláez;M.J. Martínez;A.T. Martínez

  288
  Citations

• Guggulsterone Is a Farnesoid X Receptor Antagonist in Coactivator Association Assays but Acts to Enhance Transcription of Bile Salt Export Pump

  Jisong Cui;Li Huang;Annie Zhao;Jane-L. Lew

  278
  Citations

• Microbial natural products as a source of antifungals

  M.F. Vicente;A. Basilio;A. Cabello;F. Peláez

  276
  Citations

• Discovery of FabH/FabF Inhibitors from Natural Products

  Katherine Young;Hiranthi Jayasuriya;John G. Ondeyka;Kithsiri Herath

  260
  Citations

• Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

  Hiranthi Jayasuriya;Kithsiri B. Herath;Chaowei Zhang;Deborah L. Zink

  250
  Citations

• The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion

  Jane-L. Lew;Annie Zhao;Jinghua Yu;Li Huang

  249
  Citations

• The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis. Producing organism, fermentation, isolation, and biological activity.

  Suzanne M. Mandala;Rosemary A. Thornton;Beth R. Frommer;James E. Curotto

  238
  Citations

• Geographical and seasonal influences on the distribution of fungal endophytes in Quercus ilex

  J. Collado;G. Platas;I. González;F. Peláez

  227
  Citations

• The discovery of enfumafungin, a novel antifungal compound produced by an endophytic Hormonema species biological activity and taxonomy of the producing organisms.

  Fernando Peláez;Angeles Cabello;Gonzalo Platas;María T. Díez

  196
  Citations

• Endophytic fungi from plants living on gypsum soils as a source of secondary metabolites with antimicrobial activity

  F. Peláez;J. Collado;F. Arenal;A. Basilio

  187
  Citations