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Neuroscience

D-Index
37
Citations
17572
World Ranking
8654
National Ranking
3673

Overview

Jorge J. Palop is affiliated with the University of California, San Francisco in the United States. Their research mainly focuses on Neuroscience, with significant contributions to Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work extensively covers Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Neurology, and Cognitive Neuroscience as subfields.

Their primary research topics include Neuroscience and Neuropharmacology Research, Alzheimer's disease research and treatments, Neural dynamics and brain function, CRISPR and Genetic Engineering, Neuroscience and Neural Engineering, Genetics and Neurodevelopmental Disorders, as well as Neuroinflammation and Neurodegeneration Mechanisms.

Jorge J. Palop has published multiple papers in various scientific venues. Some notable recent publications include:

  • A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease, 2020, Science Translational Medicine
  • Microglial Gi-dependent dynamics regulate brain network hyperexcitability, 2020, Nature Neuroscience
  • Identifying behavioral structure from deep variational embeddings of animal motion, 2022, Communications Biology
  • Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia, 2022, Molecular Neurodegeneration
  • GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models, 2020, Cell Reports

Frequent co-authors collaborating with Jorge J. Palop include Keran Ma, Stephanie R. Miller, Chun Chen, Reuben Thomas, and Patrick Honma. These collaborators have contributed to multiple studies alongside Palop.

Jorge J. Palop's research has been featured repeatedly in some scientific venues, including bioRxiv (Cold Spring Harbor Laboratory), Nature Neuroscience, Molecular Neurodegeneration, Cell Reports, and Alzheimer's & Dementia.

Best Publications

  • Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

    Erik D. Roberson;Kimberly Scearce-Levie;Jorge J. Palop;Fengrong Yan

  • Amyloid-[beta]-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

    Jorge J Palop;Lennart Mucke

  • Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease

    Jorge J. Palop;Jeannie Chin;Erik D. Roberson;Jun Wang

  • Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

    Laure Verret;Edward O. Mann;Giao B. Hang;Albert M.I. Barth

  • Network abnormalities and interneuron dysfunction in Alzheimer disease

    Jorge J. Palop;Lennart Mucke

  • Epilepsy and Cognitive Impairments in Alzheimer Disease

    Jorge J. Palop;Lennart Mucke

  • A network dysfunction perspective on neurodegenerative diseases

    Jorge J. Palop;Jeannie Chin;Lennart Mucke

  • Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

    Erik D. Roberson;Brian Halabisky;Jong W. Yoo;Jinghua Yao

  • Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model

    Pascal E. Sanchez;Lei Zhu;Laure Verret;Keith A. Vossel

  • Network abnormalities and interneuron dysfunction in Alzheimer’s disease: A multiscale perspective on abnormal neuronal activity in early AD

    Jorge J. Palop

  • Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models *

    Irene H. Cheng;Kimberly Scearce-Levie;Kimberly Scearce-Levie;Justin Legleiter;Justin Legleiter;Jorge J. Palop;Jorge J. Palop

  • Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

    Jorge J. Palop;Brian Jones;Lisa Kekonius;Jeannie Chin

  • Distinct roles of GABAergic interneurons in the regulation of striatal output pathways.

    Aryn H. Gittis;Alexandra B. Nelson;Myo T. Thwin;Jorge J. Palop

  • Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

    Rene O. Sanchez-Mejia;John W. Newman;Sandy Toh;Gui Qiu Yu

  • Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease

    Jeannie Chin;Jorge J Palop;Jukka Puoliväli;Catherine Massaro

  • Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network

    Julie A. Harris;Nino Devidze;Laure Verret;Kaitlyn Ho

  • Arc regulates spine morphology and maintains network stability in vivo

    Carol L. Peebles;Jong Yoo;Myo T. Thwin;Jorge J. Palop

  • What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons.

    Claudio Babiloni;Katarzyna Blinowska;Laura Bonanni;Andrej Cichocki

  • Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer’s Disease

    Magdalena Martinez-Losa;Magdalena Martinez-Losa;Tara E. Tracy;Keran Ma;Laure Verret

  • Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.

    Binggui Sun;Brian Halabisky;Yungui Zhou;Jorge J. Palop

  • Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease

    Jeannie Chin;Catherine M Massaro;Jorge J Palop;Myo T Thwin

Frequent Co-Authors

Lennart Mucke
Lennart Mucke University of California, San Francisco
Jeannie Chin
Jeannie Chin Baylor College of Medicine
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Juan Nacher
Juan Nacher University of Valencia
Anatol C. Kreitzer
Anatol C. Kreitzer University of California, San Francisco
Jeffrey L. Noebels
Jeffrey L. Noebels Baylor College of Medicine
Julie A. Harris
Julie A. Harris University of California, San Francisco
Sylvain Lesné
Sylvain Lesné University of Minnesota
Michael Gill
Michael Gill Trinity College Dublin
Louis J. Ptáček
Louis J. Ptáček University of California, San Francisco

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