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Biology and Biochemistry

D-Index
93
Citations
31522
World Ranking
2107
National Ranking
46

Overview

Jürgen Götz is affiliated with the University of Queensland in Australia and has produced extensive research primarily in the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Engineering. Their work spans several subfields, including Biomedical Engineering, Molecular Biology, Neurology, Physiology, and Radiology, Nuclear Medicine and Imaging.

The research topics they are involved with include:

  • Ultrasound and Hyperthermia Applications
  • Photoacoustic and Ultrasonic Imaging
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Barrier Structure and Function Studies
  • S100 Proteins and Annexins
  • Ultrasound Imaging and Elastography

Jürgen Götz's recent papers include:

  • The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer's disease, 2020, Current Opinion in Immunology
  • Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol, 2021, Acta Neuropathologica
  • A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease, 2021, Alzheimer s Research & Therapy
  • Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery, 2020, Stem Cell Reports
  • Fyn Kinase Controls Tau Aggregation In Vivo, 2020, Cell Reports

The main publication venues where Jürgen Götz frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry
  • Alzheimer s & Dementia
  • Acta Neuropathologica
  • Journal of Controlled Release

Frequent co-authors collaborating with Jürgen Götz are:

  • Gerhard Leinenga
  • Liviu-Gabriel Bodea
  • Rebecca M. Nisbet
  • Pranesh Padmanabhan
  • Esteban Cruz

Best Publications

  • Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

    Lars M. Ittner;Yazi D. Ke;Fabien Delerue;Mian Bi

  • Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils

    J. Götz;F. Chen;J. van Dorpe;R. M. Nitsch

  • Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

    Lars M. Ittner;Jürgen Götz

  • Animal models of Alzheimer's disease and frontotemporal dementia

    Jürgen Götz;Lars M. Ittner

  • FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations.

    Jean M. Hébert;Thomas Rosenquist;Jürgen Götz;Gail R. Martin

  • Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

    Virginie Rhein;Xiaomin Song;Andreas Wiesner;Lars M. Ittner

  • Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

    Doron Shmerling;Ivan Hegyi;Marek Fischer;Thomas Blättler

  • Tau Filament Formation in Transgenic Mice Expressing P301L Tau

    Jürgen Götz;Feng Chen;Robi Barmettler;Roger M. Nitsch

  • Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.

    J Götz;A Probst;M G Spillantini;T Schäfer

  • Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model

    Gerhard Leinenga;Jürgen Götz

  • Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

    Della C. David;Susanne Hauptmann;Isabel Scherping;Katrin Schuessel

  • The blood-brain barrier: Physiology and strategies for drug delivery.

    Rucha Pandit;Liyu Chen;Jürgen Götz

  • Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

    A. Probst;J. Götz;K. H. Wiederhold;M. Tolnay

  • Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo

    Brian DuBoff;Jürgen Götz;Mel B. Feany

  • Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies

    Juan Carlos Polanco;Chuanzhou Li;Liviu-Gabriel Bodea;Ramon Martinez-Marmol

  • Tau aggregation and its interplay with amyloid-β.

    Rebecca M. Nisbet;Juan‑Carlos Polanco;Lars M. Ittner;Jürgen Götz

  • The frontotemporal dementia-motor neuron disease continuum.

    James R Burrell;James R Burrell;Glenda M Halliday;Glenda M Halliday;Jillian J Kril;Lars M Ittner;Lars M Ittner

  • Rodent models for Alzheimer disease

    Jürgen Götz;Liviu-Gabriel Bodea;Michel Goedert

  • Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

    Janet van Eersel;Yazi D. Ke;Xin Liu;Fabien Delerue

  • Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Cα

    Jürgen Götz;Alphonse Probst;Elisabeth Ehler;Brian Hemmings

Frequent Co-Authors

Lars M. Ittner
Lars M. Ittner Macquarie University
Anne Eckert
Anne Eckert University of Basel
Roger M. Nitsch
Roger M. Nitsch University of Zurich
Glenda M. Halliday
Glenda M. Halliday University of Sydney
John R. Hodges
John R. Hodges University of Sydney
Jillian J. Kril
Jillian J. Kril University of Sydney
Alphonse Probst
Alphonse Probst University Hospital of Basel
Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Matthew C. Kiernan
Matthew C. Kiernan Royal Prince Alfred Hospital

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