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Jae K. Ryu

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
10615
World Ranking
16620
National Ranking
6874

Jae K. Ryu publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jae K. Ryu sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 89 publications — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jae K. Ryu D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jae K. Ryu sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 52 D-Index — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jae K. Ryu is affiliated with the Gladstone Institutes in the United States and has contributed extensively to the fields of medicine and neuroscience. Their research primarily intersects neurology and immunology, with additional work spanning molecular biology, pediatrics, perinatology, and cellular and molecular neuroscience.

The scientist's recent publication record highlights a focus on neuroinflammation, neurodegeneration, and immune-related mechanisms in brain pathology. Notable papers include:

  • "Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation" (2020, Nature Immunology)
  • "Microglial Gi-dependent dynamics regulate brain network hyperexcitability" (2020, Nature Neuroscience)
  • "Defining blood-induced microglia functions in neurodegeneration through multiomic profiling" (2023, Nature Immunology)
  • "Fibrin drives thromboinflammation and neuropathology in COVID-19" (2024, Nature)
  • "Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation" (2024, Journal of Neuroinflammation)

Their work frequently appears in prominent journals, with multiple publications in Nature Immunology and the Journal of Neuroinflammation, as well as contributions to Nature Neuroscience and bioRxiv. The distribution of their publications among venues includes:

  • Nature Immunology
  • Journal of Neuroinflammation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia
  • Nature Neuroscience

Jae K. Ryu collaborates regularly with several co-authors, reflecting interdisciplinary research networks. Frequent collaborators include:

  • Katerina Akassoglou
  • Zhaoqi Yan
  • Andrew S. Mendiola
  • Mark A. Petersen
  • Mario Merlini

The thematic scope of their research includes topics such as neuroinflammation and neurodegeneration mechanisms, immune cells in cancer, peroxisome proliferator-activated receptors, COVID-19 clinical research studies, dermatological and COVID-19 studies, acute ischemic stroke management, and neonatal and fetal brain pathology.

Jae K. Ryu's scientific contributions span detailed molecular and cellular investigations to clinical and pathological implications of neuroinflammation and immune activation in various brain disorders and systemic conditions like COVID-19 and traumatic brain injury.

Best Publications

  • Resolving postoperative neuroinflammation and cognitive decline

    Niccolò Terrando;Lars I Eriksson;Lars I Eriksson;Jae Kyu Ryu;Ting Yang

  • Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

    Dimitrios Davalos;Jae Kyu Ryu;Mario Merlini;Kim M. Baeten

  • A leaky blood–brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

    Jae K. Ryu;James G. McLarnon

  • Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

    Mark A. Petersen;Jae Kyu Ryu;Katerina Akassoglou;Katerina Akassoglou

  • Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-β after Vascular Damage

    Christian Schachtrup;Jae K. Ryu;Matthew J. Helmrick;Eirini Vagena

  • Upregulated Expression of Purinergic P2X7 Receptor in Alzheimer Disease and Amyloid-β Peptide-Treated Microglia and in Peptide-Injected Rat Hippocampus

    James G. McLarnon;Jae K. Ryu;Douglas G. Walker;Hyun B. Choi

  • Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.

    Mario Merlini;Victoria A. Rafalski;Pamela E. Rios Coronado;T. Michael Gill

  • Fractalkine and fractalkine receptors in human neurons and glial cells

    Kozo Hatori;Atsushi Nagai;Rochelle Heisel;Jae K. Ryu

  • Metabolic control of T H 17 and induced T reg cell balance by an epigenetic mechanism

    Tao Xu;Kelly M Stewart;Xiaohu Wang;Kai Liu

  • Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

    Jae Kyu Ryu;Mark A. Petersen;Sara G. Murray;Kim M. Baeten

  • Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase.

    Hyun B. Choi;Grant R.J. Gordon;Ning Zhou;Ning Zhou;Chao Tai

  • Modulation of the Purinergic P2X7 Receptor Attenuates Lipopolysaccharide-Mediated Microglial Activation and Neuronal Damage in Inflamed Brain

    Hyun B. Choi;Jae K. Ryu;Seung U. Kim;James G. McLarnon

  • Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease.

    Jae K Ryu;Jean Kim;Sung J Cho;Kozo Hatori

  • Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

    Mark A. Petersen;Mark A. Petersen;Jae Kyu Ryu;Kae Jiun Chang;Ainhoa Etxeberria

  • Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus.

    Jae K. Ryu;Sonia Franciosi;Prasongchai Sattayaprasert;Seung U. Kim;Seung U. Kim

  • Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.

    Jae Kyu Ryu;Victoria A. Rafalski;Anke Meyer-Franke;Ryan A. Adams

  • Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase.

    Jae K. Ryu;Hyun B. Choi;Kozo Hatori;Rochelle L. Heisel

  • Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease

    Jae K. Ryu;James G. McLarnon

  • Microglial VEGF Receptor Response Is an Integral Chemotactic Component in Alzheimer's Disease Pathology

    Jae K. Ryu;Taesup Cho;Hyun B. Choi;Yu Tian Wang

  • SIRT1 deacetylates RORγt and enhances Th17 cell generationSIRT1 regulates Th17 cell function

    Hyung W. Lim;Seung Goo Kang;Jae Kyu Ryu;Birgit Schilling

Frequent Co-Authors

Katerina Akassoglou
Katerina Akassoglou University of California, San Francisco
James G. McLarnon
James G. McLarnon University of British Columbia
Seung U. Kim
Seung U. Kim University of British Columbia
Mark H. Ellisman
Mark H. Ellisman University of California, San Diego
Scott S. Zamvil
Scott S. Zamvil University of California, San Francisco
Jay L. Degen
Jay L. Degen Cincinnati Children's Hospital Medical Center
Lennart Mucke
Lennart Mucke University of California, San Francisco
Miles D. Houslay
Miles D. Houslay King's College London
Hans Lassmann
Hans Lassmann Medical University of Vienna
Yu Tian Wang
Yu Tian Wang University of British Columbia

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Related Online Degrees & Career Pathways

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Best Scientists Citing Jae K. Ryu

Seung U. Kim

Seung U. Kim

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Katerina Akassoglou

Katerina Akassoglou

University of California, San Francisco

Publications: 29

Mervyn Maze

Mervyn Maze

University of California, San Francisco

Publications: 27

Sidney Strickland

Sidney Strickland

Rockefeller University

Publications: 26

Geoffrey Burnstock

Geoffrey Burnstock

University College London

Publications: 23

Alexei Verkhratsky

Alexei Verkhratsky

University of Manchester

Publications: 18

Berislav V. Zlokovic

Berislav V. Zlokovic

University of Southern California

Publications: 16

Henning Ulrich

Henning Ulrich

Universidade de São Paulo

Publications: 16

Kaj Blennow

Kaj Blennow

University of Gothenburg

Publications: 15

James G. McLarnon

James G. McLarnon

University of British Columbia

Publications: 14

Daniela Kaufer

Daniela Kaufer

University of California, Berkeley

Publications: 14

Pierre J. Magistretti

Pierre J. Magistretti

École Polytechnique Fédérale de Lausanne

Publications: 13

Henrik Zetterberg

Henrik Zetterberg

University of Gothenburg

Publications: 13

Jochen Buck

Jochen Buck

Cornell University

Publications: 13

Francesco Di Virgilio

Francesco Di Virgilio

University of Ferrara

Publications: 13

Lonny R. Levin

Lonny R. Levin

Cornell University

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