D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 50 Citations 7,663 143 World Ranking 13263 National Ranking 5621

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Biochemistry, Cell biology, Biophysics, Protein structure and Isothermal titration calorimetry. In his study, Chad A. Brautigam carries out multidisciplinary Biochemistry and Histone methylation research. His Cell biology research includes themes of TRIM25 and Polyubiquitin binding.

The various areas that Chad A. Brautigam examines in his Biophysics study include Flavin adenine dinucleotide, Arabidopsis thaliana, Arabidopsis and Cryptochrome, Circadian clock. Chad A. Brautigam combines subjects such as Hydrolase, Genetics, Gene and Protein folding with his study of Protein structure. His Isothermal titration calorimetry research includes elements of Calorimetry, Singular value decomposition and Biological system.

His most cited work include:

  • Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes (320 citations)
  • High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis (300 citations)
  • Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response (277 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Cell biology, Biophysics, Protein structure and Isothermal titration calorimetry. In his research, he performs multidisciplinary study on Biochemistry and Treponema. Cell biology and Mutation are frequently intertwined in his study.

Chad A. Brautigam focuses mostly in the field of Isothermal titration calorimetry, narrowing it down to matters related to Biological system and, in some cases, Work, Microscale thermophoresis, Macromolecule and Analytical Ultracentrifugation. In ATP-binding cassette transporter, Chad A. Brautigam works on issues like Operon, which are connected to Microbiology. Chad A. Brautigam has included themes like Flavin adenine dinucleotide, Flavoprotein and Flavin group in his Periplasmic space study.

He most often published in these fields:

  • Biochemistry (33.55%)
  • Cell biology (26.97%)
  • Biophysics (12.50%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (26.97%)
  • Isothermal titration calorimetry (11.18%)
  • Biochemistry (33.55%)

In recent papers he was focusing on the following fields of study:

Chad A. Brautigam mainly focuses on Cell biology, Isothermal titration calorimetry, Biochemistry, Biophysics and Treponema. His Cell biology research is multidisciplinary, incorporating perspectives in Mutation, Receptor and Importin. Chad A. Brautigam has researched Isothermal titration calorimetry in several fields, including Integral membrane protein, Biological system, Dissociation constant and Complexin.

Transport protein, Periplasmic space, Phosphorylation, Protein structure and Oxidative phosphorylation are among the areas of Biochemistry where the researcher is concentrating his efforts. His Protein structure research is multidisciplinary, incorporating elements of Endocytic cycle, Signal transducing adaptor protein and Myosin. His Biophysics study combines topics in areas such as Exocytosis and Tethering.

Between 2015 and 2021, his most popular works were:

  • Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions (120 citations)
  • Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors (68 citations)
  • Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites (67 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Chad A. Brautigam mostly deals with Cell biology, Structural biology, Plasma protein binding, Biophysics and Protein structure. His studies deal with areas such as Spindle checkpoint and Biochemistry as well as Cell biology. His multidisciplinary approach integrates Biochemistry and Myosin VI complex in his work.

The study incorporates disciplines such as SNARE complex, Lipid bilayer fusion, Synaptobrevin, Cell membrane and SNAP25 in addition to Structural biology. The concepts of his Plasma protein binding study are interwoven with issues in Antagonist and Drug discovery. His work deals with themes such as Macromolecule, Membrane, C2 domain and Presynaptic active zone, Synaptic vesicle, which intersect with Biophysics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes

Chad A Brautigam;Thomas A Steitz.
Current Opinion in Structural Biology (1998)

501 Citations

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

Sandro Keller;Carolyn Vargas;Huaying Zhao;Grzegorz Piszczek.
Analytical Chemistry (2012)

474 Citations

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

Xiaomo Jiang;Lisa N. Kinch;Chad A. Brautigam;Xiang Chen.
Immunity (2012)

381 Citations

Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.

Chad A. Brautigam;Barbara S. Smith;Zhiquan Ma;Maya Palnitkar.
Proceedings of the National Academy of Sciences of the United States of America (2004)

331 Citations

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.

Xu Zhang;Jiaxi Wu;Fenghe Du;Hui Xu.
Cell Reports (2014)

322 Citations

Calculations and Publication-Quality Illustrations for Analytical Ultracentrifugation Data.

Chad A Brautigam.
Methods in Enzymology (2015)

267 Citations

Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences

Juan L. Mendoza;André Schmidt;Qin Li;Emmanuel Nuvaga.
Cell (2012)

246 Citations

Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.

Chad A Brautigam;Thomas A Steitz.
Journal of Molecular Biology (1998)

245 Citations

Hierarchical regulation of WASP/WAVE proteins.

Shae B. Padrick;Hui Chun Cheng;Ayman M. Ismail;Sanjay C. Panchal.
Molecular Cell (2008)

225 Citations

A TOG:αβ-Tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

Pelin Ayaz;Xuecheng Ye;Patrick Huddleston;Chad A. Brautigam.
Science (2012)

221 Citations

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