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Biology and Biochemistry

D-Index
108
Citations
47433
World Ranking
1039
National Ranking
628

Medicine

D-Index
109
Citations
47845
World Ranking
5740
National Ranking
3087

Overview

Samuel D. Wright is affiliated with CSL in the United States and has contributed extensively to the field of medicine, focusing primarily on surgery, endocrinology, diabetes and metabolism, as well as cardiology and cardiovascular medicine. Their research encompasses a variety of topics related to lipoproteins, cardiovascular health, and diabetes management.

Their scholarly output includes publications on lipoproteins and cardiovascular health, diabetes and cardiovascular risks, cholesterol and lipid metabolism, diabetes treatment and management, antiplatelet therapy and cardiovascular diseases, drug transport and resistance mechanisms, and influenza virus research studies.

Recent notable papers include:

  • Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue (2023) published in Journal of Hepatology
  • ApoA-I Infusion Therapies Following Acute Coronary Syndrome: Past, Present, and Future (2022) in Current Atherosclerosis Reports
  • CSL112 (Apolipoprotein A-I [Human]) Strongly Enhances Plasma Apoa-I and Cholesterol Efflux Capacity in Post-Acute Myocardial Infarction Patients: A PK/PD Substudy of the AEGIS-I Trial (2022) in Journal of Cardiovascular Pharmacology and Therapeutics
  • Biological basis and proposed mechanism of action of CSL112 (apolipoprotein A-I [human]) for prevention of major adverse cardiovascular events in patients with myocardial infarction (2023) in European Heart Journal - Cardiovascular Pharmacotherapy
  • Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres (2020) in Arteriosclerosis Thrombosis and Vascular Biology

Frequent publication venues where Wright's work appears include:

  • Arteriosclerosis Thrombosis and Vascular Biology
  • Circulation
  • Journal of Hepatology
  • Current Atherosclerosis Reports
  • Journal of Cardiovascular Pharmacology and Therapeutics

Collaborations have been significant in Wright's career. Frequent co-authors include:

  • Bronwyn A. Kingwell
  • Danielle Duffy
  • C. Michael Gibson
  • Serge Korjian
  • Gerald Chi

Best Publications

  • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein.

    Samuel D. Wright;Robert A. Ramos;Peter S. Tobias;Richard J. Ulevitch

  • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

    Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois

  • Structure and function of lipopolysaccharide binding protein

    Ralf R. Schumann;Steven R. Leong;Gail W. Flaggs;Patrick W. Gray

  • Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

    E Hailman;H S Lichenstein;M M Wurfel;D S Miller

  • Soluble CD14 participates in the response of cells to lipopolysaccharide.

    E A Frey;D S Miller;T G Jahr;A Sundan

  • Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.

    S D Wright;P E Rao;W C Van Voorhis;L S Craigmyle

  • Human Neutrophil Fc Gamma Receptor Distribution and Structure

    Howard B. Fleit;Samuel D. Wright;Jay C. Unkeless

  • Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.

    Christian R. H. Raetz;Richard I. Ulevitch;Samuel D. Wright;Carol H. Sibley

  • Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.

    Carl Nathan;Subita Srimal;Charles Farber;Elizabeth Sanchez

  • 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.

    Xuan Fu;John G. Menke;Yuli Chen;Gaochao Zhou

  • (d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G

    Andrew K.P. Taggart;Jukka Kero;Xiaodong Gan;Tian-Quan Cai

  • Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes

    Samuel D. Wright;Samuel C. Silverstein

  • Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen

    Samuel D. Wright;Jeffrey I. Weitz;Ada J. Huang;Susan M. Levin

  • Lipopolysaccharide (LPS)-binding Protein Is Carried on Lipoproteins and Acts as a Cofactor in the Neutralization of LPS

    Mark M. Wurfel;Steven T. Kunitake;Henri Lichenstein;John P. Kane

  • Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering

    Carl P. Sparrow;Charlotte A. Burton;Melba Hernandez;Steven Mundt

  • Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

    S. D. Wright;M. T. C. Jong

  • Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes.

    Samuel D. Wright;Samuel C. Silverstein

  • Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis.

    David Relman;Elaine Tuomanen;Stanley Falkow;Douglas T. Golenbock

  • 11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

    Anne Hermanowski-Vosatka;James M. Balkovec;Kang Cheng;Howard Y. Chen

  • Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (Nature (2010) 464 (1357-1361))

    Peter Duewell;Hajime Kono;Katey J. Rayner;Cherilyn M. Sirois

Frequent Co-Authors

Samuel C. Silverstein
Samuel C. Silverstein Columbia University
Elaine I. Tuomanen
Elaine I. Tuomanen St. Jude Children's Research Hospital
David E. Moller
David E. Moller Eli Lilly (United States)
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Laurence B. Peterson
Laurence B. Peterson Roche (Switzerland)
Terje Espevik
Terje Espevik Norwegian University of Science and Technology
Richard J. Ulevitch
Richard J. Ulevitch Scripps Research Institute
Kathryn J. Moore
Kathryn J. Moore New York University Langone Medical Center
Fernando Pelaez
Fernando Pelaez Spanish National Cancer Research Centre
Sheo B. Singh
Sheo B. Singh MSD (United States)

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