World's Best Scientists 2026 revealed!

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Microbiology

D-Index
93
Citations
31123
World Ranking
589
National Ranking
272

Medicine

D-Index
93
Citations
31365
World Ranking
10899
National Ranking
5605

Overview

Elaine I. Tuomanen is affiliated with St. Jude Children's Research Hospital in the United States. Their primary focus lies within the field of Medicine, with extensive research spanning Infectious Diseases, Epidemiology, Microbiology, Molecular Biology, and Animal Science and Zoology.

The scientist's main topics of study include SARS-CoV-2 and COVID-19 Research, Pneumonia and Respiratory Infections, Bacterial Infections and Vaccines, COVID-19 Clinical Research Studies, Animal Virus Infections Studies, Pneumocystis jirovecii pneumonia detection and treatment, and Antibiotic Resistance in Bacteria.

Recent publications by Elaine I. Tuomanen cover several key findings:

  • "SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans" (2021, Cell)
  • "SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells" (2022, Nature Immunology)
  • "Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response" (2021, Cell Host & Microbe)
  • "Pneumolysin: Pathogenesis and Therapeutic Target" (2020, Frontiers in Microbiology)
  • "Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines" (2021, Vaccines)

The scientist collaborates regularly with several frequent co-authors, including Joshua Wolf, Kim Allison, Maureen A. McGargill, Richard J. Webby, and Randall T. Hayden.

Elaine I. Tuomanen publishes predominantly in the following journals and venues:

  • Cell Host & Microbe
  • Open Forum Infectious Diseases
  • Cell chemical biology
  • Frontiers in Cellular and Infection Microbiology
  • Journal of the Pediatric Infectious Diseases Society

Best Publications

  • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

    William C Sha;Hsiou-Chi Liou;Elaine I Tuomanen;David Baltimore

  • Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

    Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen

  • Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor

    Diana R. Cundell;Norma P. Gerard;Craig Gerard;Ilona Idanpaan-Heikkila

  • Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

    Karim C El Kasmi;Joseph E Qualls;John T Pesce;Amber M Smith

  • The rate of killing of Escherichia coli by beta-lactam antibiotics is strictly proportional to the rate of bacterial growth.

    E. Tuomanen;R. Cozens;W Tosch;O. Zak

  • Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway.

    A Ring;J N Weiser;E I Tuomanen

  • Use of a Whole Genome Approach To Identify Vaccine Molecules Affording Protection against Streptococcus pneumoniae Infection

    Theresa M. Wizemann;Jon H. Heinrichs;John E. Adamou;Alice L. Erwin

  • The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells

    Jing-Ren Zhang;Keith E Mostov;Michael E Lamm;Masanobu Nanno

  • The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis.

    K Saukkonen;S Sande;C Cioffe;S Wolpe

  • Pathogenesis of Pneumococcal Infection

    E I Tuomanen;R Austrian;H R Masure

  • The Pneumococcus: Epidemiology, Microbiology, and Pathogenesis

    Birgitta Henriques-Normark;Elaine I. Tuomanen

  • Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis.

    David Relman;Elaine Tuomanen;Stanley Falkow;Douglas T. Golenbock

  • Emergence of vancomycin tolerance in Streptococcus pneumoniae

    R. Novak;B. Henriques;E. Charpentier;S. Normark

  • Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes.

    E I Tuomanen;K Saukkonen;S Sande;C Cioffe

  • Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway.

    M G Cleveland;J D Gorham;T L Murphy;E Tuomanen

  • The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall

    Elaine Tuomanen;Hans Liu;Bruno Hengstler;Oto Zak

  • Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence.

    David A. Relman;Mario Domenighini;Elaine Tuomanen;Rino Rappuoli

  • Pneumococcal pneumolysin and H2O2 mediate brain cell apoptosis during meningitis

    Johann S. Braun;Jack E. Sublett;Dorette Freyer;Tim J. Mitchell

  • Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

    Carlos J. Orihuela;Geli Gao;Kevin P. Francis;Jun Yu

  • Neuroprotection by a caspase inhibitor in acute bacterial meningitis.

    J S Braun;R Novak;K H Herzog;S M Bodner

Frequent Co-Authors

Carlos J. Orihuela
Carlos J. Orihuela University of Alabama at Birmingham
Samuel D. Wright
Samuel D. Wright CSL (United States)
Peter J. Murray
Peter J. Murray Max Planck Society
Alexander Tomasz
Alexander Tomasz Rockefeller University
Scott Koenig
Scott Koenig MacroGenics (United States)
John L. Cleveland
John L. Cleveland Moffitt Cancer Center
Jonathan A. McCullers
Jonathan A. McCullers University of Tennessee Health Science Center
Staffan Normark
Staffan Normark Karolinska Institute
Norma P. Gerard
Norma P. Gerard Boston Children's Hospital
Deepak Kaushal
Deepak Kaushal Texas Biomedical Research Institute

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