Elaine Tuomanen mainly focuses on Microbiology, Streptococcus pneumoniae, Immunology, Virulence and Meningitis. Her Microbiology research includes elements of Bacterial adhesin, Virology, In vivo and Bacteria. Her Streptococcus pneumoniae study combines topics in areas such as Pathogenesis and Streptococcaceae.
Her Immunology research is multidisciplinary, incorporating perspectives in Bacteremia and Pneumonia. She interconnects Phosphorylcholine, Gene expression, Gene expression profiling and Mutant in the investigation of issues within Virulence. Her Meningitis study incorporates themes from Apoptosis, Programmed cell death and Blood–brain barrier.
Her main research concerns Microbiology, Immunology, Streptococcus pneumoniae, Biochemistry and Meningitis. The concepts of her Microbiology study are interwoven with issues in Bacterial adhesin, Virulence, Virology and Bacteria. Her Bacterial adhesin course of study focuses on Bordetella pertussis and Antibody.
Her work in Immunology tackles topics such as Pneumonia which are related to areas like Pneumococcal pneumonia and Otitis. Her Streptococcus pneumoniae research includes themes of Pathogen, Antibacterial agent and Streptococcaceae. Within one scientific family, she focuses on topics pertaining to Blood–brain barrier under Meningitis, and may sometimes address concerns connected to Cell biology.
Her primary areas of investigation include Microbiology, Streptococcus pneumoniae, Immunology, Immune system and Pneumococcal infections. Her research integrates issues of Cell, Pathogenesis, Bacterial capsule, Host and Epitope in her study of Microbiology. Her biological study spans a wide range of topics, including Meningitis, Pathogen, Haemophilus influenzae and Antigen.
The Immunology study combines topics in areas such as Bacteremia, Pneumococcal vaccine, Disease and Pneumonia. Her work deals with themes such as Heterologous, Teichoic acid, Neutropenia and Trypsin, which intersect with Immune system. Her Pneumococcal infections research incorporates themes from Cardiac function curve, Antibiotic resistance and Virulence.
Microbiology, Streptococcus pneumoniae, Immunology, Pneumococcal infections and Cell are her primary areas of study. Her work focuses on many connections between Microbiology and other disciplines, such as Neisseria meningitidis, that overlap with her field of interest in Vaccine efficacy, Virology, Haemophilus influenzae and Meningitis. Her studies in Streptococcus pneumoniae integrate themes in fields like Bacterial capsule, Immunity, Antigen and Sepsis.
Her Immunology study combines topics from a wide range of disciplines, such as Bacteremia, Stringent response and Disease. Her Pneumococcal infections study combines topics in areas such as Antibiotic resistance and Pneumolysin. Her Cell research incorporates themes from Autolysin, Antimicrobial peptides, Autolysis and N-acetylmuramoyl-L-alanine amidase.
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Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
William C Sha;Hsiou-Chi Liou;Elaine I Tuomanen;David Baltimore.
Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen.
Journal of Immunology (1999)
Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
Diana R. Cundell;Norma P. Gerard;Craig Gerard;Ilona Idanpaan-Heikkila.
Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Karim C El Kasmi;Karim C El Kasmi;Joseph E Qualls;John T Pesce;Amber M Smith.
Nature Immunology (2008)
Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway.
A Ring;J N Weiser;E I Tuomanen.
Journal of Clinical Investigation (1998)
The Rate of Killing of Escherichia coli byβ-Lactam Antibiotics Is Strictly Proportional to the Rate of Bacterial Growth
E. Tuomanen;R. Cozens;W Tosch;O. Zak.
The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis.
K Saukkonen;S Sande;C Cioffe;S Wolpe.
Journal of Experimental Medicine (1990)
Pathogenesis of Pneumococcal Infection
E I Tuomanen;R Austrian;H R Masure.
The New England Journal of Medicine (1995)
Use of a Whole Genome Approach To Identify Vaccine Molecules Affording Protection against Streptococcus pneumoniae Infection
Theresa M. Wizemann;Jon H. Heinrichs;John E. Adamou;Alice L. Erwin.
Infection and Immunity (2001)
Emergence of vancomycin tolerance in Streptococcus pneumoniae
R Novak;B Henriques;E Charpentier;S Normark.
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