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Sven Hammerschmidt

Sven Hammerschmidt

D-Index & Metrics

Microbiology

D-Index
69
Citations
14958
World Ranking
2080
National Ranking
152

Overview

Sven Hammerschmidt is affiliated with the University of Greifswald in Germany and has an extensive research portfolio primarily focused on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work intersects various subfields including epidemiology, microbiology, molecular biology, public health, environmental and occupational health, and immunology.

The main topics of Sven Hammerschmidt's research encompass pneumonia and respiratory infections, respiratory viral infections, bacterial infections and vaccines, streptococcal infections and treatments, Pneumocystis jirovecii pneumonia detection and treatment, immune response and inflammation, and influenza virus research studies.

Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microorganisms
  • Frontiers in Microbiology
  • Journal of Innate Immunity
  • Frontiers in Cellular and Infection Microbiology

The scientist has collaborated regularly with several co-authors, notably:

  • Thomas P. Kohler (28 co-authored papers)
  • Uwe Völker (14)
  • Nikolai Siemens (13)
  • Franziska Voß (12)
  • Surabhi Surabhi (9)

Recent publications by Sven Hammerschmidt include:

  • HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis, 2020, Acta Neuropathologica
  • The Role of NLRP3 Inflammasome in Pneumococcal Infections, 2020, Frontiers in Immunology
  • Proteomic Investigation Uncovers Potential Targets and Target Sites of Pneumococcal Serine-Threonine Kinase StkP and Phosphatase PhpP, 2020, Frontiers in Microbiology
  • Hydrogen Peroxide Is Crucial for NLRP3 Inflammasome-Mediated IL-1β Production and Cell Death in Pneumococcal Infections of Bronchial Epithelial Cells, 2021, Journal of Innate Immunity
  • NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections, 2023, Nature Communications

Best Publications

  • Illustration of Pneumococcal Polysaccharide Capsule during Adherence and Invasion of Epithelial Cells

    Sven Hammerschmidt;Sonja Wolff;Andreas Hocke;Simone Rosseau

  • alpha-Enolase of Streptococcus pneumoniae is a plasmin(ogen)-binding protein displayed on the bacterial cell surface.

    Simone Bergmann;Manfred Rohde;Gursharan S. Chhatwal;Sven Hammerschmidt

  • Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae.

    Bastian Opitz;Anja Püschel;Bernd Schmeck;Andreas C. Hocke

  • SpsA, a novel pneumococcal surface protein with specific binding to secretory Immunoglobulin A and secretory component

    Sven Hammerschmidt;Susanne R. Talay;Per Brandtzaeg;Gursharan S. Chhatwal

  • Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease.

    S Hammerschmidt;A Müller;H Sillmann;M Mühlenhoff

  • Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo

    Chris Oschatz;Coen Maas;Bernd Lecher;Thomas Jansen

  • Versatility of pneumococcal surface proteins.

    Simone Bergmann;Sven Hammerschmidt

  • Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pneumoniae is a surface-displayed plasminogen-binding protein.

    Simone Bergmann;Manfred Rohde;Sven Hammerschmidt

  • The pavA gene of Streptococcus pneumoniae encodes a fibronectin‐binding protein that is essential for virulence

    Ann R. Holmes;Roderick McNab;Kevin W. Millsap;Manfred Rohde

  • Platelet factor 4 binds to bacteria, inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia

    Krystin Krauel;Christian Pötschke;Claudia Weber;Wolfram Kessler

  • Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element.

    S. Hammerschmidt;R. Hilse;J. P. M. Van Putten;R. Gerardy-Schahn

  • Identification of Pneumococcal Surface Protein A as a Lactoferrin-Binding Protein of Streptococcus pneumoniae

    Sven Hammerschmidt;Gesina Bethe;Petra H. Remane;Gursharan S. Chhatwal

  • The cell wall subproteome of Listeria monocytogenes.

    Jessica Schaumburg;Oliver Diekmann;Petra Hagendorff;Simone Bergmann

  • Identification of a novel plasmin(ogen)‐binding motif in surface displayed α‐enolase of Streptococcus pneumoniae

    Simone Bergmann;Daniela Wild;Oliver Diekmann;Ronald Frank

  • PavA of Streptococcus pneumoniae Modulates Adherence, Invasion, and Meningeal Inflammation

    Daniela Pracht;Christine Elm;Joachim Gerber;Simone Bergmann

  • The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release

    Tobias Hoegen;Nadin Tremel;Matthias Klein;Barbara Angele

  • Fibrinolysis and host response in bacterial infections

    Simone Bergmann;Sven Hammerschmidt

  • Adherence molecules of pathogenic pneumococci

    Sven Hammerschmidt

  • Plasmin(Ogen)-Binding Alpha-Enolase from Streptococcus Pneumoniae: Crystal Structure and Evaluation of Plasmin(Ogen)-Binding Sites

    Stefanie Ehinger;Wolf-Dieter Schubert;Simone Bergmann;Sven Hammerschmidt

  • Species-specific binding of human secretory component to SpsA protein of Streptococcus pneumoniae via a hexapeptide motif

    Sven Hammerschmidt;Melanie P. Tillig;Sonja Wolff;Jean-Pierre Vaerman

Frequent Co-Authors

Peter F. Zipfel
Peter F. Zipfel Friedrich Schiller University Jena
Norbert Suttorp
Norbert Suttorp Charité - University Medicine Berlin
Gursharan S. Chhatwal
Gursharan S. Chhatwal Helmholtz Centre for Infection Research
Stefan Hippenstiel
Stefan Hippenstiel Charité - University Medicine Berlin
Andreas C. Hocke
Andreas C. Hocke Charité - University Medicine Berlin
Manfred Rohde
Manfred Rohde Helmholtz Centre for Infection Research
Uwe Völker
Uwe Völker University of Greifswald
Andreas Greinacher
Andreas Greinacher Greifswald University Hospital
Matthias Frosch
Matthias Frosch University of Würzburg
Uwe Koedel
Uwe Koedel Ludwig-Maximilians-Universität München

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