Syamal K. Datta

Overview

Best Publications

• Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

  Ami Desai-Mehta;Liangjun Lu;Rosalind Ramsey-Goldman;Syamal K. Datta

  801
  Citations

• Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus

  Chandra Mohan;Sharlene Adams;Valerie Stanik;Syamal K. Datta

  731
  Citations

• T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

  S Shivakumar;G C Tsokos;S K Datta

  574
  Citations

• Polyspecificity of Monoclonal Lupus Autoantibodies Produced by Human-Human Hybridomas

  Shoenfeld Y;Rauch J;Massicotte H;Datta Sk

  557
  Citations

• INTERACTION BETWEEN CD40 AND ITS LIGAND GP39 IN THE DEVELOPMENT OF MURINE LUPUS NEPHRITIS

  C. Mohan;Y. Shi;J. D. Laman;Syamal Kumar Datta

  429
  Citations

• Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis.

  S K Datta;H Patel;D Berry

  318
  Citations

• Anti-CD40 Ligand Antibody Treatment of SNF1 Mice with Established Nephritis: Preservation of Kidney Function

  Susan L. Kalled;Anne H. Cutler;Syamal K. Datta;David W. Thomas

  313
  Citations

• Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor.

  Sumati Rajagopalan;Tracy Zordan;George C. Tsokos;Syamal K. Datta

  302
  Citations

• Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells.

  Hee Kap Kang;Michael Liu;Syamal K. Datta

  273
  Citations

• Very Low-Dose Tolerance with Nucleosomal Peptides Controls Lupus and Induces Potent Regulatory T Cell Subsets

  Hee Kap Kang;Marissa A. Michaels;Beate R. Berner;Syamal K. Datta

  263
  Citations

• Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites.

  Demetrios V. Vlahakos;Mary H. Foster;Sharlene Adams;Michael Katz

  259
  Citations

• Major peptide autoepitopes for nucleosome-specific T cells of human lupus

  Liangjun Lu;Arunan Kaliyaperumal;Dimitrios T. Boumpas;Syamal K. Datta

  248
  Citations

• Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus.

  Arunan Kaliyaperumal;Chandra Mohan;Wei Wu;Syamal K. Datta

  232
  Citations

• Regulatory T Cell (Treg) Subsets Return in Patients with Refractory Lupus following Stem Cell Transplantation, and TGF-β-Producing CD8+ Treg Cells Are Associated with Immunological Remission of Lupus

  Li Zhang;Anne M. Bertucci;Rosalind Ramsey-Goldman;Richard K. Burt

  231
  Citations

• Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies☆

  Janine André-Schwartz;Janine André-Schwartz;Syamal K. Datta;Syamal K. Datta;Yehuda Schoenfeld;Yehuda Schoenfeld;David A. Isenberg;David A. Isenberg

  230
  Citations

• Antigen-Specific Therapy of Murine Lupus Nephritis Using Nucleosomal Peptides: Tolerance Spreading Impairs Pathogenic Function of Autoimmune T and B Cells

  Arunan Kaliyaperumal;Marissa A. Michaels;Syamal K. Datta

  229
  Citations

• Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo.

  Demetrios Vlahakos;Mary H. Foster;Angelo A. Ucci;Kathleen J. Barrett

  207
  Citations

• Human lupus T cells resist inactivation and escape death by upregulating COX-2.

  Luting Xu;Li Zhang;Yajun Yi;Yajun Yi;Hee Kap Kang

  201
  Citations

• Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus.

  Ami Desai-Mehta;Changchuin Mao;Sumati Rajagopalan;Tonya Robinson

  200
  Citations

• Lupus: Key Pathogenic Mechanisms and Contributing Factors

  Chandra Mohan;Syamal K. Datta

  173
  Citations