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D-Index & Metrics

Molecular Biology

D-Index
90
Citations
37552
World Ranking
731
National Ranking
394

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Philip N. Tsichlis is affiliated with The Ohio State University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with an extensive publication record covering related subfields such as molecular biology, immunology, cancer research, genetics, and oncology.

Their work encompasses various scientific topics, including:

  • RNA modifications and cancer
  • Epigenetics and DNA methylation
  • RNA research and splicing
  • Cancer-related gene regulation
  • PI3K/AKT/mTOR signaling in cancer
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research

Philip N. Tsichlis has published extensively in several scientific venues. The most frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Cancers
  • Proceedings of the National Academy of Sciences
  • Nature Communications

Recent papers authored or co-authored by Philip N. Tsichlis include:

  • Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity, 2020, Journal of Clinical Investigation
  • Akt isoforms in the immune system, 2022, Frontiers in Immunology
  • Small cell lung cancer: Subtypes and therapeutic implications, 2022, Seminars in Cancer Biology
  • Protein Arginine Methyltransferase 5 in T Lymphocyte Biology, 2020, Trends in Immunology
  • RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis, 2021, BMC Bioinformatics

The scientist collaborates frequently with several co-authors, including:

  • George Laliotis
  • Evangelia Chavdoula
  • Alessandro La Ferlita
  • Lalit Sehgal
  • Vollter Anastas

Philip N. Tsichlis has been recognized as a member of the Association of American Physicians.

Best Publications

  • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

    Thomas F Franke;Sung-Il Yang;Tung O Chan;Ketaki Datta

  • The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

    Scott G. Kennedy;Andrew J. Wagner;Suzanne D. Conzen;Joaquin Jordan

  • A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

    A Bellacosa;Testa;SP Staal;PN Tsichlis

  • Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

    Heather A. Hirsch;Dimitrios Iliopoulos;Philip N. Tsichlis;Kevin Struhl

  • AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

    Tung O. Chan;Susan E. Rittenhouse;Philip N. Tsichlis

  • TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway

    Calin D. Dumitru;Jeffrey D. Ceci;Christos Tsatsanis;Dimitris Kontoyiannis

  • AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

    Jin Quan Cheng;Andrew K. Godwin;Alfonso Bellacosa;Takahiro Taguchi

  • Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27 Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

    Giuseppe Viglietto;Maria Letizia Motti;Paola Bruni;Rosa Marina Melillo

  • The Protein Kinase Akt Induces Epithelial Mesenchymal Transition and Promotes Enhanced Motility and Invasiveness of Squamous Cell Carcinoma Lines

    Sylvia Julien Grille;Alfonso Bellacosa;John Upson;Andres J. Klein-Szanto

  • Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway

    Tomasz Skorski;Alfonso Bellacosa;Margaret Nieborowska‐Skorska;Miroslaw Majewski

  • Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.

    Andrea D. Basso;Andrea D. Basso;David B. Solit;Gabriela Chiosis;Banabihari Giri

  • Akt activation by growth factors is a multiple-step process: the role of the PH domain.

    Alfonso Bellacosa;Tung O Chan;Naheed N Ahmed;Ketaki Datta

  • The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

    Ariadne Androulidaki;Dimitrios Iliopoulos;Alicia Arranz;Christina Doxaki

  • Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway *

    Robin C. Muise-Helmericks;H. Leighton Grimes;Alfonso Bellacosa;Scott E. Malstrom

  • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

    N N Ahmed;H L Grimes;A Bellacosa;T O Chan

  • AKT1/PKBα Kinase Is Frequently Elevated in Human Cancers and Its Constitutive Activation Is Required for Oncogenic Transformation in NIH3T3 Cells

    Mei Sun;Gen Wang;June E. Paciga;Richard I. Feldman

  • Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

    Warren G. King;Mark D. Mattaliano;Tung O. Chan;Philip N. Tsichlis

  • Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

    Alicia Arranz;Christina Doxaki;Eleni Vergadi;Yeny Martinez de la Torre

  • Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.

    Hwai Wen Chang;Masahiro Aoki;David Fruman;Kurt R. Auger

  • Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

    Dimitrios Iliopoulos;Marianne Lindahl-Allen;Christos Polytarchou;Heather A. Hirsch

Frequent Co-Authors

Alfonso Bellacosa
Alfonso Bellacosa Fox Chase Cancer Center
Aristides G. Eliopoulos
Aristides G. Eliopoulos National and Kapodistrian University of Athens
Christos Tsatsanis
Christos Tsatsanis University of Crete
Pedro A. Lazo
Pedro A. Lazo University of Salamanca
John M. Coffin
John M. Coffin Tufts University
Dimitrios Iliopoulos
Dimitrios Iliopoulos University of California, Los Angeles
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Joseph R. Testa
Joseph R. Testa Fox Chase Cancer Center

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