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Biology and Biochemistry

D-Index
85
Citations
43455
World Ranking
3065
National Ranking
80

Overview

Peter Friedl is affiliated with Radboud University Medical Center in the Netherlands. Their research primarily focuses on topics within Biochemistry, Genetics and Molecular Biology as well as Medicine. The main subfields of study include Cell Biology, Biomedical Engineering, Oncology, Immunology, and Molecular Biology.

Friedl's research covers several specific topics, among which are:

  • Cellular Mechanics and Interactions
  • 3D Printing in Biomedical Research
  • Cancer Cells and Metastasis
  • Microtubule and mitosis dynamics
  • Cell Image Analysis Techniques
  • CAR-T cell therapy research
  • Advanced Fluorescence Microscopy Techniques

The scientist has contributed to numerous publications, with a concentration in several key venues including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 9 publications
  • Science Advances with 3 publications
  • Nature Cell Biology with 2 publications
  • Cancer Immunology Immunotherapy with 2 publications
  • The Journal of Cell Biology with 2 publications

Among the recent papers authored or co-authored by Friedl are:

  • "Cell-cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion," 2020, Nature Cell Biology
  • "Towards targeting of shared mechanisms of cancer metastasis and therapy resistance," 2022, Nature Reviews. Cancer
  • "Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity," 2021, Nature Communications
  • "p120-catenin-dependent collective brain infiltration by glioma cell networks," 2020, Nature Cell Biology
  • "Multiphoton fluorescence microscopy for in vivo imaging," 2024, Cell

Frequent co-authors of Friedl include:

  • Bettina Weigelin
  • Gert-Jan Bakker
  • Esther Wagena
  • Maria Parlani
  • Katarina Wolf

Best Publications

  • Tumour-cell invasion and migration: diversity and escape mechanisms

    Peter Friedl;Katarina Wolf

  • Collective cell migration in morphogenesis, regeneration and cancer

    Peter Friedl;Darren Gilmour

  • Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

    Peter Friedl;Peter Friedl;Peter Friedl;Stephanie Alexander;Stephanie Alexander

  • Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis

    Katarina Wolf;Irina Mazo;Harry Leung;Katharina Engelke

  • Plasticity of cell migration: a multiscale tuning model

    Peter Friedl;Peter Friedl;Katarina Wolf

  • Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

    Katarina Wolf;Mariska te Lindert;Marina Krause;Stephanie Alexander

  • Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

    Katarina Wolf;Yi I. Wu;Yi I. Wu;Yueying Liu;Jörg Geiger

  • Nuclear envelope rupture and repair during cancer cell migration

    Celine M. Denais;Rachel M. Gilbert;Philipp Isermann;Alexandra L. McGregor

  • Classifying collective cancer cell invasion

    Peter Friedl;Joseph Locker;Erik Sahai;Jeffrey E. Segall

  • The biology of cell locomotion within three-dimensional extracellular matrix.

    Peter Friedl;E. B. Bröcker

  • Prespecification and plasticity: shifting mechanisms of cell migration.

    Peter Friedl

  • Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three‐Dimensional Imaging of Living Cells

    Jan Dommerholt;Samuel Schmidt;Rinske Temming;Linda J. A. Hendriks

  • Collagen-based cell migration models in vitro and in vivo

    Katarina Wolf;Stephanie Alexander;Vivien Schacht;Lisa M. Coussens

  • Interstitial leukocyte migration and immune function.

    Peter Friedl;Bettina Weigelin

  • Collective Cell Migration in Morphogenesis and Cancer

    Peter Friedl;Yael Hegerfeldt;Miriam Tusch

  • Nuclear mechanics during cell migration

    Peter Friedl;Katarina Wolf;Jan Lammerding

  • Antigen Presentation in Extracellular Matrix: Interactions of T Cells with Dendritic Cells Are Dynamic, Short Lived, and Sequential

    Matthias Gunzer;Matthias Gunzer;Angelika Schäfer;Stefan Borgmann;Stephan Grabbe

  • Mechanoreciprocity in cell migration.

    Sjoerd van Helvert;Cornelis Storm;Peter Friedl

  • Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases.

    Katarina Wolf;Katarina Wolf;Regina Müller;Regina Müller;Stefan Borgmann;Stefan Borgmann;Eva.-B. Bröcker;Eva.-B. Bröcker

  • Collective cell migration: guidance principles and hierarchies

    Anna Haeger;Katarina Wolf;Mirjam M. Zegers;Peter Friedl

Frequent Co-Authors

Kurt S. Zänker
Kurt S. Zänker Witten/Herdecke University
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Dietmar W. Hutmacher
Dietmar W. Hutmacher Queensland University of Technology
Eva-B. Bröcker
Eva-B. Bröcker University of Würzburg
Carl G. Figdor
Carl G. Figdor Radboud University
Eckhart Kämpgen
Eckhart Kämpgen University of Erlangen-Nuremberg
Robert M. Hoffman
Robert M. Hoffman AntiCancer (United States)
Jan Lammerding
Jan Lammerding Cornell University
Christopher J. Logothetis
Christopher J. Logothetis The University of Texas MD Anderson Cancer Center
Herbert Levine
Herbert Levine Northeastern University

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