Nissim Hay

Research.com Recognitions

• 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Upstream and downstream of mTOR

  Nissim Hay;Nahum Sonenberg

  5313
  Citations

• The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

  Scott G. Kennedy;Andrew J. Wagner;Suzanne D. Conzen;Joaquin Jordan

  1373
  Citations

• The pentose phosphate pathway and cancer.

  Krushna C. Patra;Nissim Hay;Nissim Hay

  1353
  Citations

• Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene

  William S. Chen;Pei Zhang Xu;Kathrin Gottlob;Mei Ling Chen

  1210
  Citations

• The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

  Eugene S. Kandel;Nissim Hay

  1199
  Citations

• AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

  Sang Min Jeon;Navdeep S. Chandel;Nissim Hay

  1172
  Citations

• 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

  Anne Claude Gingras;Scott G. Kennedy;Maura A. O'Leary;Nahum Sonenberg

  1131
  Citations

• Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

  Kathrin Gottlob;Nathan Majewski;Scott Kennedy;Scott Kennedy;Eugene Kandel

  1122
  Citations

• Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2

  Xiao ding Peng;Pei Zhang Xu;Mei Ling Chen;Annett Hahn-Windgassen

  1019
  Citations

• The two TORCs and Akt.

  Prashanth T. Bhaskar;Nissim Hay

  1015
  Citations

• Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?

  Nissim Hay

  998
  Citations

• The Akt-mTOR tango and its relevance to cancer.

  Nissim Hay

  938
  Citations

• Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis.

  Veronique Nogueira;Youngkyu Park;Chia Chen Chen;Pei Zhang Xu

  864
  Citations

• Akt/Protein Kinase B Inhibits Cell Death by Preventing the Release of Cytochrome c from Mitochondria

  Scott G. Kennedy;Eugene S. Kandel;Torry K. Cross;Nissim Hay

  847
  Citations

• Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

  Krushna C. Patra;Qi Wang;Prashanth T. Bhaskar;Luke Miller

  816
  Citations

• Hexokinase-Mitochondria Interaction Mediated by Akt Is Required to Inhibit Apoptosis in the Presence or Absence of Bax and Bak

  Nathan Majewski;Veronique Nogueira;Prashanth Bhaskar;Platina E. Coy;Platina E. Coy

  759
  Citations

• Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

  Andrew J. Wagner;John M. Kokontis;Nissim Hay

  748
  Citations

• Akt Activates the Mammalian Target of Rapamycin by Regulating Cellular ATP Level and AMPK Activity

  Annett Hahn-Windgassen;Véronique Nogueira;Chia Chen Chen;Jennifer E. Skeen

  691
  Citations

• Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.

  R. Brooks Robey;R. Brooks Robey;Nissim Hay

  665
  Citations

• Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt

  R B Robey;N Hay

  653
  Citations