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Molecular Biology

D-Index
53
Citations
10309
World Ranking
2389
National Ranking
1182

Overview

Angela L. Tyner is affiliated with the University of Illinois at Chicago in the United States. Their research spans multiple fields, primarily focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these fields, their work engages deeply with oncology, immunology, and molecular biology subfields, reflecting a multidisciplinary approach to cancer and immune system research.

The scientist's recent publications emphasize molecular mechanisms and immune responses, particularly in cancer biology. Notable papers include:

  • Targeting protein tyrosine kinase 6 in cancer, 2020, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Appearance of tuft cells during prostate cancer progression, 2023, Oncogene
  • Protein tyrosine kinase 6 regulates activation of SRC kinase, 2022, Journal of Biological Chemistry
  • Impaired activation of succinate-induced type 2 immunity and secretory cell production in the small intestines of Ptk6−/− male mice, 2024, Cell Death and Disease
  • Mo1221 PROTEIN TYROSINE KINASE 6 (PTK6) DIFFERENTIALLY REGULATES TYPE 2 IMMUNITY IN THE INTESTINE IN A SEX-DEPENDENT MANNER, 2023, Gastroenterology

Their research topics cover:

  • Cytokine Signaling Pathways and Interactions
  • Melanoma and MAPK Pathways
  • HER2/EGFR in Cancer Research
  • Immune cells in cancer
  • Biochemical Analysis and Sensing Techniques
  • Cancer-related molecular mechanisms research
  • Immune Cell Function and Interaction

Angela L. Tyner collaborates frequently with several researchers including Katarina Vlajic, Wenjun Bie, Milica B. Gilic, Andre Kajdacsy-Balla, and Hannah Pennington. Their work has been published in journals such as Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Oncogene, Journal of Biological Chemistry, Cell Death and Disease, and Gastroenterology.

The scientist's studies often explore the regulation and roles of protein tyrosine kinase 6 (PTK6) in cancer progression and immune regulation. This includes investigating sex-dependent immune responses and the activation of immune pathways in intestinal and prostate cancer contexts.

Best Publications

  • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

    Andrei L. Gartel;Angela L. Tyner

  • Transcriptional Regulation of the p21(WAF1/CIP1)Gene

    Andrei L. Gartel;Angela L. Tyner

  • P21 : NEGATIVE REGULATOR OF THE CELL CYCLE

    Andrei L. Gartel;Michael S. Serfas;Angela L. Tyner

  • Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3

    Andrei L. Gartel;Xin Ye;Eugene Goufman;Pavel Shianov

  • Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

    Robert Vassar;Marjorie Rosenberg;Susan Ross;Angela Tyner

  • FoxM1, a critical regulator of oxidative stress during oncogenesis

    Hyun Jung Park;Janai R Carr;Zebin Wang;Veronique Nogueira

  • Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability.

    Jason J. Derry;Stéphane Richard;Héctor Valderrama Carvajal;Xin Ye

  • Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin.

    Do Y. Lim;Yoonhwa Jeong;Angela L. Tyner;Jung H. Y. Park

  • Deregulation of FoxM1b leads to tumour metastasis.

    Hyun Jung Park;Galina A. Gusarova;Zebin Wang;Janai R. Carr

  • Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis.

    Angela L. Tyner;Elaine Fuchs

  • FoxM1 Regulates Transcription of JNK1 to Promote the G1/S Transition and Tumor Cell Invasiveness

    I-Ching Wang;Yi-Ju Chen;Douglas E. Hughes;Timothy Ackerson

  • Functional analysis and intracellular localization of p53 modified by SUMO-1.

    Serena S. S. Kwek;Jason Derry;Angela L. Tyner;Zhiyuan Shen;Zhiyuan Shen

  • The human keratin genes and their differential expression.

    Elaine Fuchs;Angela L. Tyner;George J. Giudice;Douglas Marchuk

  • Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line.

    Han J. Cho;Woo K. Kim;Eun J. Kim;Kyeong C. Jung

  • p21 (WAF1/CIP1) Expression Is Induced in Newly Nondividing Cells in Diverse Epithelia and during Differentiation of the Caco-2 Intestinal Cell Line

    Andrei L. Gartel;Michael S. Serfas;Medeia Gartel;Eugene Goufman

  • Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase.

    Hyun Jung Park;Robert H. Costa;Lester F. Lau;Angela L. Tyner

  • The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes.

    Angela L. Tyner;Margaret J. Eichman;Elaine Fuchs

  • Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression.

    Kiven Erique Lukong;Daniel Larocque;Angela L. Tyner;Stéphane Richard

  • Brk, Srm, Frk, and Src42A form a distinct family of intracellular Src-like tyrosine kinases.

    Michael S. Serfas;Angela L. Tyner

  • Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells.

    Jason J Derry;Gail S Prins;Vera Ray;Angela L Tyner

Frequent Co-Authors

Pradip Raychaudhuri
Pradip Raychaudhuri University of Illinois at Chicago
Robert H. Costa
Robert H. Costa University of Illinois at Chicago
Lester F. Lau
Lester F. Lau University of Illinois at Chicago
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
Elaine Fuchs
Elaine Fuchs Rockefeller University
Nissim Hay
Nissim Hay University of Illinois at Chicago
Jung Han Yoon Park
Jung Han Yoon Park Hallym University
Ralf Wagner
Ralf Wagner University of Regensburg
Terry G. Unterman
Terry G. Unterman University of Illinois at Chicago
Douglas A. Marchuk
Douglas A. Marchuk Duke University

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